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Chemical Structure| 88683-57-2 Chemical Structure| 88683-57-2

Structure of 88683-57-2

Chemical Structure| 88683-57-2

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Product Details of [ 88683-57-2 ]

CAS No. :88683-57-2
Formula : C11H8N2O2S
M.W : 232.26
SMILES Code : N#CCCSN(C(C1=C2C=CC=C1)=O)C2=O
MDL No. :MFCD01863529
InChI Key :MVZDBGUIRMGSOY-UHFFFAOYSA-N
Pubchem ID :4067398

Safety of [ 88683-57-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 88683-57-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 88683-57-2 ]

[ 88683-57-2 ] Synthesis Path-Downstream   1~14

  • 1
  • [ 136918-14-4 ]
  • [ 1001-58-7 ]
  • [ 88683-57-2 ]
YieldReaction ConditionsOperation in experiment
58% With chlorine; triethylamine; In dichloromethane; N,N-dimethyl-formamide; N-(2-cyanoethylmercapto)phthalimide 21 A Solution of chlorine in dichloromethane (1.4 mol dm-3, 10.0 cm3, 14.0 mmol) was added dropwise to a stirred solution of 2-cyanoethyl mercaptan, (see, for example, Bauer and Welsh, loc cit), (1.22 g, 14.0 mmol) in dichloromethane (21 cm3) at 0 C. (ice-water bath). After the products had been allowed to warm to room temperature, they were added dropwise to a stirred slurry of phthalimide (1.47 g, 10.0 mmol) and triethylamine (1.94 cm3, 14.0 mmol) in dry DMF (12 cm3) at 0 C. (ice-water bath). The stirred reactants were allowed to warm to room temperature. After 2 h, the products were poured into saturated aqueous sodium hydrogen carbonate (25 cm3) and the resulting mixture was extracted with dichloromethane (2*50 cm3). The combined organic layers were dried (MgSO4) and concentrated under reduced pressure. The residue was crystallized from ethanol to give N-(2-cyanoethylmercapto)phthalimide 21 as colourless needles (1.345 g, 58%) (Found: C, 57.0; H, 3.4; N, 11.8. C11 H8 N2 O2 S requires: C, 56.9; H, 3.5; N, 12.1%), m.p. 162-164 C.; deltaH ?CDCl3! 2.79 (2 H, t, J7.2), 3.12 (2 H, t, J7.2), 7.83 (2 H, m), 7.95 (2 H, m); deltaC ?CDCl3! 18.7, 34.5, 117.5, 124.1, 131.7, 134.9, 168.1.
  • 2
  • [ 15715-58-9 ]
  • [ 88683-57-2 ]
  • C35H43N2O9PSi2 [ No CAS ]
  • S-(2-cyanoethyl) 5'-O-(9-phenylxanthen-9-yl)thymidine 3'-(hydrogen-phosphorothioate) triethylammonium salt [ No CAS ]
  • 3
  • [ 15715-58-9 ]
  • [ 88683-57-2 ]
  • C41H48N3O7PSi2 [ No CAS ]
  • 4-N-benzoyl-5'-O-(9-phenylxanthen-9-yl)-2'-deoxycitidine S-(2-cyanoethyl) 3'-(hydrogen phosphorothioate) triethylammonium salt [ No CAS ]
  • 4
  • [ 15715-58-9 ]
  • [ 88683-57-2 ]
  • C40H50N5O7PSi2 [ No CAS ]
  • S-(2-cyanoethyl) 5'-O-(9-phenylxanthen-9-yl)-6-N-pivaloyl-2'-deoxyadenosine hydrogen 3'-phosphorothioate triethylammonium salt [ No CAS ]
  • 5
  • [ 15715-58-9 ]
  • [ 88683-57-2 ]
  • C43H48N5O8PSi2 [ No CAS ]
  • S-(2-cyanoethyl) 2-N-phenylacetyl-5'-O-(9-phenylxanthen-9-yl)-2'-deoxyguanosine 3'-(hydrogen phosphorothioate) triethylammonium salt [ No CAS ]
  • 6
  • [ 88683-57-2 ]
  • Triethylammonium 2'-deoxy-6-O-(2,5-dichlorophenyl)-5'-O-(4,4'-dimethoxytrityl)-2-N-isobutyrylguanosine 3'-H-phosphonate [ No CAS ]
  • Thiophosphoric acid O-{(2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-[6-(2,5-dichloro-phenoxy)-2-isobutyrylamino-purin-9-yl]-tetrahydro-furan-3-yl} ester S-(2-cyano-ethyl) ester; compound with triethyl-amine [ No CAS ]
  • 7
  • [ 88683-57-2 ]
  • C87H91Cl4N17O30P4S3*C6H15N [ No CAS ]
  • C90H94Cl4N18O30P4S4*C6H15N [ No CAS ]
  • 8
  • [ 88683-57-2 ]
  • C41H45N5O18P2S*C6H15N [ No CAS ]
  • C44H48N6O18P2S2*C6H15N [ No CAS ]
  • 9
  • [ 88683-57-2 ]
  • C64H63Cl4N11O15P2S*C6H15N [ No CAS ]
  • C67H66Cl4N12O15P2S2*C6H15N [ No CAS ]
  • 10
  • [ 88683-57-2 ]
  • C39H39N2O11P*C6H15N [ No CAS ]
  • Thiophosphoric acid O-{(2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-[3-(4-methoxy-benzoyl)-5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl]-tetrahydro-furan-3-yl} ester S-(2-cyano-ethyl) ester; compound with triethyl-amine [ No CAS ]
  • 11
  • [ 603-76-9 ]
  • [ 88683-57-2 ]
  • N-methyl-3-(2-cyanoethyl)thio-1H-indole [ No CAS ]
  • 12
  • [ 88683-57-2 ]
  • ammonium bis-S-(2-cyanoethyl) phosphorodithioate [ No CAS ]
  • 13
  • [ 1009796-72-8 ]
  • [ 1009796-75-1 ]
  • [ 88683-57-2 ]
  • [ 1092479-23-6 ]
  • 14
  • [ 1092479-25-8 ]
  • [ 88683-57-2 ]
  • C80H78Cl6N14O16P2S2 [ No CAS ]
 

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