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Chemical Structure| 87428-52-2 Chemical Structure| 87428-52-2
Chemical Structure| 87428-52-2

2-Hydroxy-1-(3-methoxyphenyl)ethanone

CAS No.: 87428-52-2

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Cat. No.: A422950 Purity: 98%

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Product Details of [ 87428-52-2 ]

CAS No. :87428-52-2
Formula : C9H10O3
M.W : 166.17
SMILES Code : COC1=CC(C(CO)=O)=CC=C1
MDL No. :MFCD16165831

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Application In Synthesis of [ 87428-52-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 87428-52-2 ]

[ 87428-52-2 ] Synthesis Path-Upstream   1~2

  • 1
  • [ 87428-52-2 ]
  • [ 100-52-7 ]
  • [ 26964-24-9 ]
YieldReaction ConditionsOperation in experiment
89% at 70℃; for 6 h; In 10 ml in the reaction kettle, successively added 0.3183g (3mmol) benzaldehyde, 0.3323g (2mmol) 5-methoxy-2-hydroxy acetophenone and 0.2630g (0.6mmol) of the ionic liquid catalyst [Bmim]2[MoO4] (structural formula refer to embodiment 1), and 0.8170g (8mmol) tetrahydrofururyl alcohol solvent, stirring after mixing, heating to reaction temperature 70 °C, in 0.4 MPa stir to react under oxygen atmosphere 6h, cooled to the room temperature after the reaction, the solvent is removed by reduced pressure distillation after of tetrahydrofurfuryl alcohol, adding ethyl acetate and water extraction, the split-phase, passes through the column again chromatography and recrystallization of relative separation to obtain the target product 6-methoxy-flavone, the yield is 89percent, by nuclear magnetic resonance hydrogen spectrum, carbon spectrum and high-resolution mass spectrometry to determine its structural formula is:
References: [1] Patent: CN105294627, 2016, A, . Location in patent: Paragraph 0097; 0098; 0099.
  • 2
  • [ 87428-52-2 ]
  • [ 98-88-4 ]
  • [ 26964-24-9 ]
References: [1] Synthetic Communications, 2013, vol. 43, # 11, p. 1549 - 1556.
 

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• Appel Reaction • Baeyer-Villiger Oxidation • Barbier Coupling Reaction • Baylis-Hillman Reaction • Bucherer-Bergs Reaction • Buchwald-Hartwig C-N Bond and C-O Bond Formation Reactions • Chugaev Reaction • Clemmensen Reduction • Corey-Bakshi-Shibata (CBS) Reduction • Corey-Chaykovsky Reaction • Corey-Kim Oxidation • Dess-Martin Oxidation • Fischer Indole Synthesis • Grignard Reaction • Henry Nitroaldol Reaction • Horner-Wadsworth-Emmons Reaction • Hydride Reductions • Jones Oxidation • Lawesson's Reagent • Leuckart-Wallach Reaction • Martin's Sulfurane Dehydrating Reagent • McMurry Coupling • Meerwein-Ponndorf-Verley Reduction • Mitsunobu Reaction • Moffatt Oxidation • Nomenclature of Ethers • Oxidation of Alcohols by DMSO • Passerini Reaction • Paternò-Büchi Reaction • Petasis Reaction • Peterson Olefination • Pictet-Spengler Tetrahydroisoquinoline Synthesis • Preparation of Alcohols • Preparation of Aldehydes and Ketones • Preparation of Amines • Preparation of Ethers • Prins Reaction • Reactions of Alcohols • Reactions of Aldehydes and Ketones • Reactions of Amines • Reactions of Benzene and Substituted Benzenes • Reactions of Ethers • Reactions with Organometallic Reagents • Reformatsky Reaction • Ritter Reaction • Robinson Annulation • Schlosser Modification of the Wittig Reaction • Schmidt Reaction • Sharpless Olefin Synthesis • Specialized Acylation Reagents-Ketenes • Stobbe Condensation • Swern Oxidation • Tebbe Olefination • Ugi Reaction • Wittig Reaction • Wolff-Kishner Reduction

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