Home Cart Sign in  
Chemical Structure| 86996-25-0 Chemical Structure| 86996-25-0

Structure of 86996-25-0

Chemical Structure| 86996-25-0

*Storage: .

*Shipping: Normal

N-(4-Oxocyclohexyl)isobutyramide

CAS No.: 86996-25-0

,98%

4.5 *For Research Use Only !

Cat. No.: A1870474 Purity: 98%

Change View

Size Price

US Stock

Global Stock

In Stock

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

    In Stock

    - +

    US Stock: ship in 0-1 business day
    Global Stock: ship in 2 weeks

    • 1-2 Day Shipping
    • High Quality
    • Technical Support
    Product Citations

    Alternative Products

    Product Details of [ 86996-25-0 ]

    CAS No. :86996-25-0
    Formula : C10H17NO2
    M.W : 183.25
    SMILES Code : CC(C)C(NC1CCC(CC1)=O)=O
    MDL No. :MFCD12106624

    Safety of [ 86996-25-0 ]

    Application In Synthesis of [ 86996-25-0 ]

    * All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

    • Downstream synthetic route of [ 86996-25-0 ]

    [ 86996-25-0 ] Synthesis Path-Downstream   1~1

    • 1
    • [ 86996-25-0 ]
    • [ 6971-45-5 ]
    • [ 918792-66-2 ]
    YieldReaction ConditionsOperation in experiment
    4% With acetyl chloride; In ethanol; for 57h;Heating / reflux; Preparation 7N-(8-methoxy-2,3,4,9-tetrahydro-lH-carbazol-3-yl)-isobutyramideAdd acetyl chloride (34.1 mL, 480 mmol) portionwise to absolute ethanol (120 mL) cooled in an ice bath and stir for 2 h. Add 4-methoxyphenylhydrazine hydrochloride (1.74 g, 10 mmol) and N-(4-oxo-cyclohexyl)-isobutyramide (Preparation 2) (1.83 g, 120 mmol) and reflux with stirring for 18 h. Follow the procedures essentially as described in Preparation 6, above, to give 6.0 g green gum after workup. Pass over a silica pad eluting with dichloromethane/25% ethyl acetate to provide 1.29 g of a brown foam. Further purify the residue by flash EPO <DP n="90"/>chromatography, eluting with dichloromethane, dichloromethane/25% ethyl acetate and then a gradient up to dichloromethane/40% ethyl acetate to obtain a pale tan solid. Triturate in diethyl ether with a bit of hexane to give 421 mg (4%) of an off- white solid. MS (ES): m/z 287 (M+l), 285 (M-I); 1H NMR(DMS0-d6): delta 10.77 (s, IH), 7.83 (d, IH, J = 7.5 Hz), 6.95 (d, IH, J = 7.9 Hz), 6.86 (t, IH, J = 7.7 Hz), 6.61 (d, IH, J = 7.5 Hz), 4.02 (m, IH), 3.90 (s, 3H), 2.89 (dd, IH, J = 15.0, 5.3 Hz), 2.76 (m, 2H), 2.50-2.34 (m, 3H), 1.95 (m, IH), 1.76 (m, IH), 1.03 (d, 6H, / = 7.0 Hz).
     

    Historical Records