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Chemical Structure| 868-84-8 Chemical Structure| 868-84-8

Structure of 868-84-8

Chemical Structure| 868-84-8

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Product Details of [ 868-84-8 ]

CAS No. :868-84-8
Formula : C3H6OS2
M.W : 122.21
SMILES Code : O=C(SC)SC
MDL No. :MFCD00144163

Safety of [ 868-84-8 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H315-H318-H335-H227-H410
Precautionary Statements:P210-P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P310-P330-P332+P313-P362-P370+P378-P403+P233-P403+P235-P405-P501-P273
Class:9
UN#:3334
Packing Group:

Application In Synthesis of [ 868-84-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 868-84-8 ]

[ 868-84-8 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 868-84-8 ]
  • [ 3386-35-4 ]
  • [ 3698-95-1 ]
  • 2
  • [ 868-84-8 ]
  • [ 4403-69-4 ]
  • [ 66655-67-2 ]
  • 3
  • [ 757251-39-1 ]
  • [ 868-84-8 ]
  • [ 320-51-4 ]
  • [ 755037-03-7 ]
YieldReaction ConditionsOperation in experiment
96.2% With tetra(n-butyl)ammonium hydroxide; In tetrahydrofuran; at 35℃; for 1.33333h;Green chemistry; The above 47 mmol of intermediate I, 3-trifluoromethyl-4-chloroaniline 46 mmol and 0.425 mmol of tetrabutylammonium hydroxide were dissolved in 80 mL of tetrahydrofuran.50 mmol of dimethyl sulphate was added dropwise in portions, and the mixture was heated to 35 C for 80 min, cooled to room temperature, and the reaction mixture was concentrated under reduced pressure, and then added to 90 mL of CH2Cl2-EtOAc (7:2).Stir, layer, respectively, wash with 30mL 5% HCl, 50mL H2O, dry Na2SO4,Filtration, concentration under reduced pressure, at least, and solids were precipitated to give a crude product of 21.16 g of crude product, 95.3%. _: Example 3-1 Regohini pure product 10 g of the crude product was added to 150 mL of water, stirred well, and the pH was adjusted to 2.0 to 2.5 with a 10% diluted aqueous hydrochloric acid solution, and stirred at room temperature.The crude product is dissolved and filtered to obtain a crude solution, and the organic impurities are extracted with diethyl ether, and the organic phase is separated;To the aqueous layer, a 6% sodium hydrogencarbonate solution was added dropwise, the pH was adjusted to 6.5-7.0, and the reaction product was precipitated and suction filtered to obtain a solid;The obtained solid was dissolved in 50 mL of diethyl ether, activated carbon was added, and heated to 30 C.Stir well, filter to obtain the filtrate, after stirring, separate the organic layer, (3 * 20mL) H2O wash, dry, filtered, distilled ether to give a thick liquid product,The viscous liquid product is added to cold water, crystals are precipitated, crystallized, filtered, and drained.A white solid was obtained, which was dried in vacuo to give 9.92 g of the crude product of rugofene, yield 96.2%, purity 99.99%.
 

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