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Chemical Structure| 854584-01-3 Chemical Structure| 854584-01-3
Chemical Structure| 854584-01-3

6-Bromo-3,4-dihydroquinoxalin-2(1H)-one

CAS No.: 854584-01-3

4.5 *For Research Use Only !

Cat. No.: A559320 Purity: 98%

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Product Details of [ 854584-01-3 ]

CAS No. :854584-01-3
Formula : C8H7BrN2O
M.W : 227.06
SMILES Code : O=C1NC2=C(C=C(Br)C=C2)NC1
MDL No. :MFCD19689712
InChI Key :AFHCUZXZHPMRQJ-UHFFFAOYSA-N
Pubchem ID :66911307

Safety of [ 854584-01-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 854584-01-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 854584-01-3 ]

[ 854584-01-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 854584-01-3 ]
  • [ 55687-34-8 ]
YieldReaction ConditionsOperation in experiment
70% With dihydrogen peroxide; sodium hydroxide; In water; at 0 - 80℃; for 3.5h; A suspension of compound 38 (850 mg) in 10 % aqueous NaOH (10 ml) was slowly added 25 % H202 (5 ml) at 0C while stirring. The reaction mixture was stirred at 0-C for lh and then allowed to stir at room temperature for 2 h (till clear solution was . formed) . Once the clear solution was formed, it was stirred at 80C for half an hour. The mixture was cooled to 0C, and then AcOH was added slowly thereto till pH 7. The solid was collected by filtration and dried under vacuum to give the title compound 39 (600 mg, 70%) . 1HNMR (400 MHz, DMSO-d6) delta: 12.46 (brs, 1H) , 8.20 (s, 1H) , 7.98 ? (d, J= 2.4 Hz, 1H) , 7.70 (dd, J = 8.8, 2.0 Hz, 1H) , 7.25 (d, J = 8.4 Hz, 2H) .
 

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Technical Information

• Acyl Group Substitution • Alkyl Halide Occurrence • Baeyer-Villiger Oxidation • Barbier Coupling Reaction • Baylis-Hillman Reaction • Bucherer-Bergs Reaction • Chan-Lam Coupling Reaction • Clemmensen Reduction • Complex Metal Hydride Reductions • Corey-Bakshi-Shibata (CBS) Reduction • Corey-Chaykovsky Reaction • Fischer Indole Synthesis • General Reactivity • Grignard Reaction • Henry Nitroaldol Reaction • Hiyama Cross-Coupling Reaction • Horner-Wadsworth-Emmons Reaction • Hydride Reductions • Kinetics of Alkyl Halides • Kumada Cross-Coupling Reaction • Lawesson's Reagent • Leuckart-Wallach Reaction • McMurry Coupling • Meerwein-Ponndorf-Verley Reduction • Passerini Reaction • Paternò-Büchi Reaction • Petasis Reaction • Peterson Olefination • Pictet-Spengler Tetrahydroisoquinoline Synthesis • Preparation of Aldehydes and Ketones • Preparation of Amines • Prins Reaction • Reactions of Aldehydes and Ketones • Reactions of Alkyl Halides with Reducing Metals • Reactions of Amines • Reactions of Dihalides • Reformatsky Reaction • Robinson Annulation • Schlosser Modification of the Wittig Reaction • Schmidt Reaction • Specialized Acylation Reagents-Carbodiimides and Related Reagents • Specialized Acylation Reagents-Ketenes • Stille Coupling • Stobbe Condensation • Substitution and Elimination Reactions of Alkyl Halides • Suzuki Coupling • Tebbe Olefination • Ugi Reaction • Wittig Reaction • Wolff-Kishner Reduction

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