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Chemical Structure| 850568-44-4 Chemical Structure| 850568-44-4

Structure of 850568-44-4

Chemical Structure| 850568-44-4

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Product Details of [ 850568-44-4 ]

CAS No. :850568-44-4
Formula : C10H13BO4
M.W : 208.02
SMILES Code : O=C(OC)CCC1=CC=C(B(O)O)C=C1
MDL No. :MFCD04115640
InChI Key :XRKIHUXCUIFHAS-UHFFFAOYSA-N
Pubchem ID :3779933

Safety of [ 850568-44-4 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 850568-44-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 850568-44-4 ]

[ 850568-44-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 850568-44-4 ]
  • [ 1187932-25-7 ]
  • C23H29NO4 [ No CAS ]
YieldReaction ConditionsOperation in experiment
83% Synthesis of Compound 6b: A mixture of 6a (900 mg, 3 mmol), 4-(2- methoxycarbonylethyl) phenylboronic acid (624 mg, 3 mmol) in 1,2-dimethoxyethane (10 mL) and potassium carbonate (828 mg, 6 mmol) in water (2 mL), was stirred at room temperature. Tetrakis(triphenylphosphine)palladium(0) (172 mg, 0.15 mmol) was added and the reaction mixture was heated at 100C in a microwave reactor for 1 hour. The organic layer wasseparated. The organic layer was filtered through a hydrophobic frit and the filtrate was evaporated. The residue was purified by silica gel chromatography using a gradient of isohexanes/ethyl acetate 20:1 to 5:1 to afford the title compound (958 mg, 83%) as a white solid.
 

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