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Chemical Structure| 85-38-1 Chemical Structure| 85-38-1
Chemical Structure| 85-38-1

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Product Details of 3-Nitrosalicylic acid

CAS No. :85-38-1
Formula : C7H5NO5
M.W : 183.12
SMILES Code : O=C(O)C1=CC=CC([N+]([O-])=O)=C1O
MDL No. :MFCD00024240
InChI Key :WWWFHFGUOIQNJC-UHFFFAOYSA-N
Pubchem ID :6807

Safety of 3-Nitrosalicylic acid

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of 3-Nitrosalicylic acid

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 85-38-1 ]

[ 85-38-1 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 832710-65-3 ]
  • [ 85-38-1 ]
  • [ 1383453-27-7 ]
YieldReaction ConditionsOperation in experiment
To a solution of 3-nitrosalicyclic acid (500 mg, 2.73 mmol) in dichloromethane (10 mL) is added oxalylchloride (2 M in dichloromethane, 1.50 ml, 3 mmol) and three drops of N,N-dimethylformamide. The mixture is stirred at room temperature overnight. The solvent is evaporated under vacuum to leave a crude residue, a portion of which (127 mg, 0.63 mmol) is dissolved in dichloromethane (5 mL) and the solution cooled to 0 C. Triethylamine (0.22 mL, 1.57 mmol) is added followed by <strong>[832710-65-3]2,8-diaza-spiro[4.5]decan-1-one hydrochloride</strong> (100 mg, 0.52 mmol). The mixture is allowed to warm to room temperature and stirred overnight. Water is added, the phases separated, the organic layer dried over MgSO4 and evaporated under reduced pressure to give compound 1-1.Yield: 200 mgES mass spectrum: [M+H]+=320Retention time: 0.69 min (HPLC method 2)
  • 2
  • [ 85-38-1 ]
  • [ 1086378-35-9 ]
 

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