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Chemical Structure| 82670-28-8 Chemical Structure| 82670-28-8

Structure of 82670-28-8

Chemical Structure| 82670-28-8

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Product Details of [ 82670-28-8 ]

CAS No. :82670-28-8
Formula : C3H8ClNO2S
M.W : 157.62
SMILES Code : CS(=O)(N(CCl)C)=O
MDL No. :MFCD19232091

Safety of [ 82670-28-8 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H315-H318-H335
Precautionary Statements:P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P310-P330-P332+P313-P362-P403+P233-P405-P501
Class:8
UN#:3261
Packing Group:

Application In Synthesis of [ 82670-28-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 82670-28-8 ]

[ 82670-28-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 82670-28-8 ]
  • [ 937-19-9 ]
  • methyl 5-cyano-1-[methyl(methylsulfonyl)amino]methyl}-1H-pyrrole-2-carboxylate [ No CAS ]
YieldReaction ConditionsOperation in experiment
84% General procedure: A solution of 1a - g (10 mmol, 1 eq) in anhydrous DMF (10 mL) was added to slurry of sodium hydride (60 % w/w; 0.48 g, 12 mmol, 1.2 eq) in anhydrous DMF (50 mL) at 0 C over 15 min. The reaction mass was warmed to room temperature and stirred for 1 h, and again cooled to 0 C. Then 2 (1.90 g, 12 mmol, 1.2 eq) was added over 15 min and the reaction mixture stirred at room temperature for 18 h. The mixture was poured into ice-water (200 mL) and the mixture was extracted with EtOAc (3 × 50 mL). The organic layer was washed with water (2 × 30 mL), 1M solution of K2CO3 (20 mL), and brine (20 mL), dried over anhydrous Na2SO4 and concentrated under reduced pressure. The residue was purified by recrystallization. General procedure for 3a was scaled up 5 times.
 

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