Home Cart Sign in  
Chemical Structure| 70958-18-8 Chemical Structure| 70958-18-8
Chemical Structure| 70958-18-8

1-(5-Chloro-2-phenoxyphenyl)ethan-1-one

CAS No.: 70958-18-8

4.5 *For Research Use Only !

Cat. No.: A926133 Purity: 95%

Change View

Size Price

US Stock

Global Stock

In Stock
5g łÇóÿ¶ÊÊ Inquiry Inquiry
10g ł§Çÿ¶ÊÊ Inquiry Inquiry

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 5g

    łÇóÿ¶ÊÊ

  • 10g

    ł§Çÿ¶ÊÊ

In Stock

- +

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support Online Technical Q&A
Product Citations

Alternative Products

Product Details of [ 70958-18-8 ]

CAS No. :70958-18-8
Formula : C14H11ClO2
M.W : 246.69
SMILES Code : CC(C1=CC(Cl)=CC=C1OC2=CC=CC=C2)=O

Safety of [ 70958-18-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Application In Synthesis of [ 70958-18-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 70958-18-8 ]

[ 70958-18-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 70958-18-8 ]
  • [ 70958-20-2 ]
YieldReaction ConditionsOperation in experiment
67.1% Example 14. Synthesis of 5-chloro-2-phenoxyphenylacetic acid (compound XIVa) [Show Image] A mixture of 200 g (0.81 mol) of 5-chloro-2-phenoxyacetophenone (compound XV), as obtained in Example 13, 112.3 g (1.29 mol) of morpholine and 40 g (1.25 mol) of sulfur was stirred at 110 ºC for 12 hours. After cooling to room temperature, 1 L of glacial acetic acid and 1 L of concentrated aqueous hydrochloric acid were added, and the resulting mixture was stirred at reflux temperature for 8 hours. The reaction mixture was concentrated to about 1/3 of its initial volume. Then, 800 mL of water and 800 mL of methyl tert-butyl ether were added. The aqueous layer was separated, washed with 400 mL of methyl tert-butyl ether, and discarded. The organic phases were combined and washed subsequently with 1 x 500 mL and 2 x 250 mL of an 8 % aqueous solution of sodium carbonate. The aqueous phases were combined, washed with 2 x 200 mL of methyl tert-butyl ether, and acidified to pH 1 with concentrated hydrochloric acid. 400 mL of petroleum ether were added, and the resulting mixture was stirred at room temperature for 30 minutes. The suspension was filtered, and the solid was dried until constant weight to obtain 143 g of 5-chloro-2-phenoxyphenylacetic acid (compound XIVa). Yield: 67.1 %.
 

Historical Records