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Chemical Structure| 703-59-3 Chemical Structure| 703-59-3

Structure of 703-59-3

Chemical Structure| 703-59-3

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Product Details of [ 703-59-3 ]

CAS No. :703-59-3
Formula : C9H6O3
M.W : 162.14
SMILES Code : O=C1OC(CC2=C1C=CC=C2)=O
MDL No. :MFCD00006894
InChI Key :AKHSBAVQPIRVAG-UHFFFAOYSA-N
Pubchem ID :12801

Safety of [ 703-59-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 703-59-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 703-59-3 ]

[ 703-59-3 ] Synthesis Path-Downstream   1~9

  • 1
  • [ 615-55-4 ]
  • [ 703-59-3 ]
  • [ 137840-21-2 ]
  • 2
  • [ 703-59-3 ]
  • triethylorthoformate [ No CAS ]
  • [ 521-73-3 ]
  • 3
  • [ 703-59-3 ]
  • [ 116986-13-1 ]
  • [ 1324006-67-8 ]
YieldReaction ConditionsOperation in experiment
2.49 g With triethylamine; In acetonitrile; for 10h;Reflux; General procedure: General Procedure for the Preparation of 7-Aza-5,6-dihydro-5-oxo-11H-indeno[1,2-c]isoquinolines 12-14 [0111] 3-Methylpicolonitrile (10, 3.0-4.0 g, 25.4-33.9 mmol, 1 equiv), NBS (6.78-9.04 g, 38.1-50.8 mmol, 1.5 equiv), and AIBN (0.42-0.56 g, 2.5-3.4 mmol, 0.1 equiv) were diluted with 1,2-dichloroethane (80-100 mL), and the reaction mixture was heated at reflux for 2 h. The reaction mixture was concentrated to half its original volume, filtered, and the filtrate was concentrated to dryness to provide crude 11. Compound 11 was diluted with acetonitrile (100-125 mL). The appropriate homophthalic anhydride (5, 6, or 7, 6.8-12.4 g, 41.9-55.9 mmol, 1.65 equiv) was added, followed by triethylamine (18-24 mL, 127.0-169.5 mmol, 5 equiv), and the solution was heated at reflux for 10 h. The solution was allowed to cool to room temperature, and the precipitate was filtered and washed with hot acetonitrile (2×35 mL) to provide the described compound. RRN 47-Aza-5,6-dihydro-5-oxo-11H-indeno[1,2-c]isoquinoline (12) [0112] The general procedure provided the described compound as a gray solid (2.49 g, 31%): mp 267-269 C. IR (KBr) 3098, 1665, 1573, 1478, 767, and 756 cm-1; 1H NMR (DMSO-d6) delta 12.18 (s, 1H), 8.56 (dd, J=4.9 and 1.3 Hz, 1H), 8.30 (d, J=8.0 Hz, 1H), 8.02 (dd, J=7.5 and 1.1 Hz, 1H), 7.82-7.80 (m, 2H), 7.57-7.51 (m, 1H), 7.36 (dd, J=7.5 and 5.0 Hz, 1H), 3.94 (s, 2H); ESIMS m/z (rel intensity) 235 (MH+, 100). Anal. Calcd for C15H10N2O: C, 76.91; H, 4.30; N, 11.96. [0113] Found: C, 76.58; H, 4.16; N, 11.80.
  • 4
  • [ 52351-75-4 ]
  • [ 703-59-3 ]
  • C18H13NO6 [ No CAS ]
  • 5
  • [ 52351-75-4 ]
  • [ 703-59-3 ]
  • (3S,4'S)-methyl 6-methoxy-1',2-dioxospiro[indoline-3,3'-isochroman]-4'-carboxylate [ No CAS ]
  • 6
  • [ 391-12-8 ]
  • [ 703-59-3 ]
  • C18H10F3NO5 [ No CAS ]
  • C18H10F3NO5 [ No CAS ]
  • 7
  • [ 4079-54-3 ]
  • [ 703-59-3 ]
  • 3-[2-(4-methylphenyl)-2-oxo-ethyl]isobenzofuran-1(3H)-one [ No CAS ]
  • 8
  • [ 64611-67-2 ]
  • [ 703-59-3 ]
  • [ 69322-20-9 ]
  • 9
  • [ 703-59-3 ]
  • [ 521-73-3 ]
 

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Technical Information

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[ 703-59-3 ]

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