Home Cart Sign in  
Chemical Structure| 660432-43-9 Chemical Structure| 660432-43-9
Chemical Structure| 660432-43-9

(2-Fluoro-4-nitrophenyl)methanol

CAS No.: 660432-43-9

4.5 *For Research Use Only !

Cat. No.: A203192 Purity: 97%

Change View

Size Price

US Stock

Global Stock

In Stock
100mg łËǶÊÊ Inquiry Inquiry
250mg ł§Ê¶ÊÊ Inquiry Inquiry
1g łÍ§¶ÊÊ Inquiry Inquiry
5g łËÊ˶ÊÊ Inquiry Inquiry

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 100mg

    łËǶÊÊ

  • 250mg

    ł§Ê¶ÊÊ

  • 1g

    łÍ§¶ÊÊ

  • 5g

    łËÊ˶ÊÊ

In Stock

- +

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support Online Technical Q&A
Product Citations

Alternative Products

Product Details of [ 660432-43-9 ]

CAS No. :660432-43-9
Formula : C7H6FNO3
M.W : 171.13
SMILES Code : OCC1=CC=C([N+]([O-])=O)C=C1F
MDL No. :MFCD11110168
InChI Key :XYGZVFTWIGGORD-UHFFFAOYSA-N
Pubchem ID :17981733

Safety of [ 660432-43-9 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Calculated chemistry of [ 660432-43-9 ] Show Less

Physicochemical Properties

Num. heavy atoms 12
Num. arom. heavy atoms 6
Fraction Csp3 0.14
Num. rotatable bonds 2
Num. H-bond acceptors 4.0
Num. H-bond donors 1.0
Molar Refractivity 41.35
TPSA ?

Topological Polar Surface Area: Calculated from
Ertl P. et al. 2000 J. Med. Chem.

66.05 Ų

Lipophilicity

Log Po/w (iLOGP)?

iLOGP: in-house physics-based method implemented from
Daina A et al. 2014 J. Chem. Inf. Model.

1.33
Log Po/w (XLOGP3)?

XLOGP3: Atomistic and knowledge-based method calculated by
XLOGP program, version 3.2.2, courtesy of CCBG, Shanghai Institute of Organic Chemistry

0.97
Log Po/w (WLOGP)?

WLOGP: Atomistic method implemented from
Wildman SA and Crippen GM. 1999 J. Chem. Inf. Model.

1.49
Log Po/w (MLOGP)?

MLOGP: Topological method implemented from
Moriguchi I. et al. 1992 Chem. Pharm. Bull.
Moriguchi I. et al. 1994 Chem. Pharm. Bull.
Lipinski PA. et al. 2001 Adv. Drug. Deliv. Rev.

0.78
Log Po/w (SILICOS-IT)?

SILICOS-IT: Hybrid fragmental/topological method calculated by
FILTER-IT program, version 1.0.2, courtesy of SILICOS-IT, http://www.silicos-it.com

-0.05
Consensus Log Po/w?

Consensus Log Po/w: Average of all five predictions

0.9

Water Solubility

Log S (ESOL):?

ESOL: Topological method implemented from
Delaney JS. 2004 J. Chem. Inf. Model.

-1.75
Solubility 3.04 mg/ml ; 0.0178 mol/l
Class?

Solubility class: Log S scale
Insoluble < -10 < Poorly < -6 < Moderately < -4 < Soluble < -2 Very < 0 < Highly

Very soluble
Log S (Ali)?

Ali: Topological method implemented from
Ali J. et al. 2012 J. Chem. Inf. Model.

-1.94
Solubility 1.94 mg/ml ; 0.0114 mol/l
Class?

Solubility class: Log S scale
Insoluble < -10 < Poorly < -6 < Moderately < -4 < Soluble < -2 Very < 0 < Highly

Very soluble
Log S (SILICOS-IT)?

SILICOS-IT: Fragmental method calculated by
FILTER-IT program, version 1.0.2, courtesy of SILICOS-IT, http://www.silicos-it.com

-1.88
Solubility 2.25 mg/ml ; 0.0131 mol/l
Class?

Solubility class: Log S scale
Insoluble < -10 < Poorly < -6 < Moderately < -4 < Soluble < -2 Very < 0 < Highly

Soluble

Pharmacokinetics

GI absorption?

Gatrointestinal absorption: according to the white of the BOILED-Egg

High
BBB permeant?

BBB permeation: according to the yolk of the BOILED-Egg

Yes
P-gp substrate?

P-glycoprotein substrate: SVM model built on 1033 molecules (training set)
and tested on 415 molecules (test set)
10-fold CV: ACC=0.72 / AUC=0.77
External: ACC=0.88 / AUC=0.94

No
CYP1A2 inhibitor?

Cytochrome P450 1A2 inhibitor: SVM model built on 9145 molecules (training set)
and tested on 3000 molecules (test set)
10-fold CV: ACC=0.83 / AUC=0.90
External: ACC=0.84 / AUC=0.91

No
CYP2C19 inhibitor?

Cytochrome P450 2C19 inhibitor: SVM model built on 9272 molecules (training set)
and tested on 3000 molecules (test set)
10-fold CV: ACC=0.80 / AUC=0.86
External: ACC=0.80 / AUC=0.87

No
CYP2C9 inhibitor?

Cytochrome P450 2C9 inhibitor: SVM model built on 5940 molecules (training set)
and tested on 2075 molecules (test set)
10-fold CV: ACC=0.78 / AUC=0.85
External: ACC=0.71 / AUC=0.81

No
CYP2D6 inhibitor?

Cytochrome P450 2D6 inhibitor: SVM model built on 3664 molecules (training set)
and tested on 1068 molecules (test set)
10-fold CV: ACC=0.79 / AUC=0.85
External: ACC=0.81 / AUC=0.87

No
CYP3A4 inhibitor?

Cytochrome P450 3A4 inhibitor: SVM model built on 7518 molecules (training set)
and tested on 2579 molecules (test set)
10-fold CV: ACC=0.77 / AUC=0.85
External: ACC=0.78 / AUC=0.86

No
Log Kp (skin permeation)?

Skin permeation: QSPR model implemented from
Potts RO and Guy RH. 1992 Pharm. Res.

-6.66 cm/s

Druglikeness

Lipinski?

Lipinski (Pfizer) filter: implemented from
Lipinski CA. et al. 2001 Adv. Drug Deliv. Rev.
MW ≤ 500
MLOGP ≤ 4.15
N or O ≤ 10
NH or OH ≤ 5

0.0
Ghose?

Ghose filter: implemented from
Ghose AK. et al. 1999 J. Comb. Chem.
160 ≤ MW ≤ 480
-0.4 ≤ WLOGP ≤ 5.6
40 ≤ MR ≤ 130
20 ≤ atoms ≤ 70

None
Veber?

Veber (GSK) filter: implemented from
Veber DF. et al. 2002 J. Med. Chem.
Rotatable bonds ≤ 10
TPSA ≤ 140

0.0
Egan?

Egan (Pharmacia) filter: implemented from
Egan WJ. et al. 2000 J. Med. Chem.
WLOGP ≤ 5.88
TPSA ≤ 131.6

0.0
Muegge?

Muegge (Bayer) filter: implemented from
Muegge I. et al. 2001 J. Med. Chem.
200 ≤ MW ≤ 600
-2 ≤ XLOGP ≤ 5
TPSA ≤ 150
Num. rings ≤ 7
Num. carbon > 4
Num. heteroatoms > 1
Num. rotatable bonds ≤ 15
H-bond acc. ≤ 10
H-bond don. ≤ 5

1.0
Bioavailability Score?

Abbott Bioavailability Score: Probability of F > 10% in rat
implemented from
Martin YC. 2005 J. Med. Chem.

0.55

Medicinal Chemistry

PAINS?

Pan Assay Interference Structures: implemented from
Baell JB. & Holloway GA. 2010 J. Med. Chem.

0.0 alert
Brenk?

Structural Alert: implemented from
Brenk R. et al. 2008 ChemMedChem

2.0 alert: heavy_metal
Leadlikeness?

Leadlikeness: implemented from
Teague SJ. 1999 Angew. Chem. Int. Ed.
250 ≤ MW ≤ 350
XLOGP ≤ 3.5
Num. rotatable bonds ≤ 7

No; 1 violation:MW<1.0
Synthetic accessibility?

Synthetic accessibility score: from 1 (very easy) to 10 (very difficult)
based on 1024 fragmental contributions (FP2) modulated by size and complexity penaties,
trained on 12'782'590 molecules and tested on 40 external molecules (r2 = 0.94)

1.65

Application In Synthesis of [ 660432-43-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 660432-43-9 ]

[ 660432-43-9 ] Synthesis Path-Downstream   1~27

  • 1
  • [ 660432-43-9 ]
  • [ 157701-72-9 ]
YieldReaction ConditionsOperation in experiment
30% With manganese(IV) oxide; In dichloromethane; at 20℃; Add borane-tetrahydrofuran complex (16.21 [ML,] [1] M) to a mixture of 2-fluoro-4- nitro-benzoic acid (1.2 g) and tetrahydrofuran (10 [ML)] at [0C.] Heat at [80C] for 3 hours. Cool at room temperature and add 1 N aqueous hydrochloric acid (20 mL) and extract with ethyl acetate. Wash with saturated aqueous sodium bicarbonate and dry the remaining organic phase over sodium sulfate and concentrate under reduced pressure to provide (0.91 g, 83%) of an oil. Add (2-fluoro-4-nitro-phenyl) -methanol (0.91 g) to a mixture of dioxide manganese (1.1 g) in 20 ml of dichloromethane. Stir at room temperature overnight and filter over [CELITE&COMMAT;. ] Concentrate under reduced pressure to provide (0.27 g, 30%) of the title compound as an oil.
With sulfur trioxide pyridine complex; triethylamine; In dimethyl sulfoxide; at 20℃; for 2h; 43.3 g of 2-fluoro-4-nitrobenzoic acid was dissolved in 600 ml of dimethylformamide, and 1,1'-carbodiimide was added to it, and stirred at room temperature for 2 hours. 11.1 g of sodium borohydride was added thereto, and further stirred for 30 minutes. Aqueous saturated ammonium chloride solution was added to it, 800 ml of water was added thereto, extracted wit 1.2 liters of ethyl acetate, and the organic layer was washed with saturated saline water. The solvent was evaporated away under reduced pressure, the residue was again diluted with ethyl acetate, and the organic layer was washed with water and saturated saline water. This was dried with anhydrous sodium sulfate, and the solvent was evaporated away to obtain 32.7 g of a brown oil. The obtained oil was dissolved in 200 ml of dimethyl sulfoxide and 60 ml of triethylamine, and 88.7 g of sulfur trioxide/pyridine complex was gradually added to it, and stirred at room temperature for 2 hours. This was diluted with ethyl acetate, and the organic layer was washed with water, aqueous 0.1 N hydrochloric acid solution and saturated saline water. The solvent was evaporated away under reduced pressure, and the residue was purified through silica gel column chromatography (developing solvent: hexane/ethyl acetate) and through crystallization (methanol/diethyl ether) to obtain 14.0 g of the entitled compound as an orange solid.
  • 2
  • [ 660432-43-9 ]
  • [ 55728-64-8 ]
  • [ 1972-28-7 ]
  • [ 1057344-36-1 ]
YieldReaction ConditionsOperation in experiment
With triphenylphosphine; In pyridine; Example 10 Uridine 5'-monophosphate (2-fluoro-4-nitrobenzyl)ester A solution of 2',3'- O-isopropylidene-uridine 5'-monophosphoric acid (0.2 mmol) and <strong>[660432-43-9]2-fluoro-4-nitrobenzyl alcohol</strong> (0.4 mmol) in pyridine (5 mL) is treated with triphenylphosphine (6 mmol) and diethylazodicarboxylate (4 mmol) 7 hours at 28 C. The solvents are removed in vacuo and the residue chromatographed on silica gel with methanol-chloroform as eluent, to isolate 2',3'-O-isopropylidene-uridine 5'-monophosphate (2-fluoro-4-nitrobenzyl)ester. This compound is treated with methanolic HCl 20 minutes at 28 C., and the solvent removed in vacuo to afford the title compound.
  • 3
  • [ 403-24-7 ]
  • [ 660432-43-9 ]
YieldReaction ConditionsOperation in experiment
43.3 g of 2-fluoro-4-nitrobenzoic acid was dissolved in 600 ml of dimethylformamide, and 1,1'-carbodiimide was added to it, and stirred at room temperature for 2 hours. 11.1 g of sodium borohydride was added thereto, and further stirred for 30 minutes. Aqueous saturated ammonium chloride solution was added to it, 800 ml of water was added thereto, extracted wit 1.2 liters of ethyl acetate, and the organic layer was washed with saturated saline water. The solvent was evaporated away under reduced pressure, the residue was again diluted with ethyl acetate, and the organic layer was washed with water and saturated saline water. This was dried with anhydrous sodium sulfate, and the solvent was evaporated away to obtain 32.7 g of a brown oil. The obtained oil was dissolved in 200 ml of dimethyl sulfoxide and 60 ml of triethylamine, and 88.7 g of sulfur trioxide/pyridine complex was gradually added to it, and stirred at room temperature for 2 hours. This was diluted with ethyl acetate, and the organic layer was washed with water, aqueous 0.1 N hydrochloric acid solution and saturated saline water. The solvent was evaporated away under reduced pressure, and the residue was purified through silica gel column chromatography (developing solvent: hexane/ethyl acetate) and through crystallization (methanol/diethyl ether) to obtain 14.0 g of the entitled compound as an orange solid.
With lithium aluminium tetrahydride; In diethyl ether; at 0℃; for 0.75h;Reflux; General procedure: To a stirred suspension of LiAlH4 (3.0mmol) in ether was added dropwise a solution of 21 in ether at 0C over 15min. The mixture was refluxed for 30min, then the reaction cooled to 0C and quenched with 1N HCl. The precipitate was filtered off and washed with ether. The combined filtrate was dried over MgSO4, filtered and concentrated in vacuo. The residue was puried by column chromatography on silica gel to afford the desired product.
  • 5
  • [ 127-88-8 ]
  • [ 660432-43-9 ]
  • C11H13Cl3FN2O4P [ No CAS ]
  • 7
  • C13H7FN4O4 [ No CAS ]
  • [ 660432-43-9 ]
  • 8
  • [ 660432-43-9 ]
  • [ 98-59-9 ]
  • [ 1412457-41-0 ]
YieldReaction ConditionsOperation in experiment
39.2% With sodium hydroxide; In tetrahydrofuran; at 5 - 20℃; for 4h; To a mixture of 4-nitrobenzyl alcohol or <strong>[660432-43-9]4-nitro-2-fluorobenzyl alcohol</strong> (1.1 eq) in THF and aq. NaOH solution (5 M, 1.5 eq), 4-methylbenzenesulfonyl chloride (1.0 eq) in THF was added dropwise over 1 h at 5 ºC. The reaction was stirred at r.t. for another 3 h. The precipitate was filtered, washed thoroughly with water, dried, and then recrystallized from methanol to give the desired tosylate. 4-Nitro-2-fluorobenzyl tosylate: 41.0 mg (39.2% yield) was obtained from 55 mg of <strong>[660432-43-9]4-nitro-2-fluorobenzyl alcohol</strong>. LC-MS (ESI+, m/z): 325.6 [M+H]+
  • 9
  • [ 660432-43-9 ]
  • C23H32F3N3O8 [ No CAS ]
  • 10
  • [ 660432-43-9 ]
  • [ 1412457-34-1 ]
  • 11
  • [ 660432-43-9 ]
  • [ 1412457-36-3 ]
  • 12
  • [ 660432-43-9 ]
  • [ 1412457-40-9 ]
  • 13
  • [ 660432-43-9 ]
  • 1,1'-carbonyldiimidazole [ No CAS ]
  • 4-nitro-2-fluorobenzyloxycarbonyl imidazole [ No CAS ]
YieldReaction ConditionsOperation in experiment
90.6% In tetrahydrofuran; at 20℃; for 2h; Carbonyldiimidazole (CDI, 1.1 eq) was added to a solution of 4-nitrobenzyl alcohol or <strong>[660432-43-9]4-nitro-2-fluorobenzyl alcohol</strong> (1.0 eq) in THF (10 mL), and the mixture was stirred at r.t. for 2 h before quenching with cold H2O (10 mL). After the solvent was removed, the residue was extracted with CH2Cl2 (3×10 mL) and the combined organic layer was washed with H2O and brine, dried over MgSO4, concentrated in vacuo to afford the desired 4-nitrobenzyloxycarbonyl imidazole as a colorless solid. 4-Nitro-2-fluorobenzyloxycarbonyl imidazole: 421 mg (90.6% yield) was obtained from 300 mg of <strong>[660432-43-9]4-nitro-2-fluorobenzyl alcohol</strong>. LC-MS (ESI+, m/z): 266.0 [M+H]+
  • 14
  • [ 392-09-6 ]
  • [ 660432-43-9 ]
YieldReaction ConditionsOperation in experiment
94% With methanol; sodium tetrahydroborate; at 23℃; for 4h; Step 1 : To a stirred solution of methyl 2-fluoro-4-nitrobenzoate (10.0 g, 49.7 mmol, 1 eq.) in methanol (100 mL) was added sodium borohydride (9.40 g, 248.7 mmol, 5 eq.) at RT and stirred for 4h. The methanol was evaporated and the residue was diluted with ethyl acetate (50 mL x 2) washed with water (50 mL) and brine (50 mL). The ethyl acetate layer was dried over Na2S04, evaporated under vacuum to get (2-fluoro-4-nitrophenyl)methanol (8 g, 94%, off-white solid; TLC system: EtOAc/PE (3:7), Rf: 0.30).
94% With methanol; sodium tetrahydroborate; at 23℃; for 4h; Step 1 : To a stirred solution of methyl 2-fluoro-4-nitrobenzoate (10.0 g, 49.7 mmol, 1 eq.) in methanol (100 mL) was added sodium borohydride (9.40 g, 248.7 mmol, 5 eq.) at RT and stirred for 4h. The methanol was evaporated and the residue was diluted with ethyl acetate (50 mL x 2) washed with water (50 mL) and brine (50 mL). The ethyl acetate layer was dried over Na2SO4, evaporated under vacuum to get (2-fluoro-4-nitrophenyl)methanol (8 g, 94%, off-white solid; TLC system: EtOAc/PE (3:7), Rf: 0.30).
3.6 g With methanol; sodium tetrahydroborate; at 20℃; for 4.5h; Into a 500-mL round-bottom flask, was placed methyl 2-fluoro-4-nitrobenzoate (10 g, 50.2 mmol) in methanol (100 mL). This was followed by the addition of NaBH4 (9.5 g, 251 mmol) in portions over 30 mm. The resulting solution was stirred for 4 h at RT. The resulting solution was diluted with 400 mL of ethyl acetate. The resulting mixture was washed with 200 mL ofwater and 200 mL of brine. The organic layer was dried over anhydrous sodium sulfate andthen concentrated. This resulted in 3.6 g of the title compound as an off white solid. MS-ESI:172 (M+1).
  • 15
  • [ 660432-43-9 ]
  • [ 1402581-51-4 ]
  • 16
  • [ 660432-43-9 ]
  • [ 1402581-52-5 ]
  • 17
  • [ 660432-43-9 ]
  • [ 1402581-53-6 ]
  • 18
  • [ 660432-43-9 ]
  • [ 1402581-54-7 ]
  • 19
  • [ 660432-43-9 ]
  • [ 1402581-55-8 ]
  • 20
  • [ 660432-43-9 ]
  • [ 1402581-58-1 ]
  • 21
  • [ 660432-43-9 ]
  • [ 840501-15-7 ]
YieldReaction ConditionsOperation in experiment
48% With palladium 10% on activated carbon; hydrogen; In ethyl acetate; at 23℃; for 6h; Step 2: To a stirred solution of <strong>[660432-43-9](2-fluoro-4-nitrophenyl)methanol</strong> (3.0 g, 1 .0 eq.) in EtOAc (30 mL) was added 10% Pd-C and the reaction mixture was stirred under H2 gas balloon at RT for 6 h. The reaction mixture was passed through a celite pad and the solvent evaporated. The residue was purified by neutral alumina column using PE/EtOAc (3:2) as eluent to get (4-amino-2-fluorophenyl)methanol (1 .1 g, 48%) as a solid; TLC system: EtOAc/PE (1 :1 ), Rf: 0.3).
48% With palladium 10% on activated carbon; hydrogen; In ethyl acetate; at 23℃; for 6h; Step 2: To a stirred solution of <strong>[660432-43-9](2-fluoro-4-nitrophenyl)methanol</strong> (3.0 g, 1 .0 eq.) in EtOAc (30 mL) was added 10% Pd-C and the reaction mixture was stirred under H2 gas balloon at RT for 6 h. The reaction mixture was passed through a celite pad and the solvent evaporated. The residue was purified by neutral alumina column using PE/EtOAc (3:2) as eluent to get (4-amino-2-fluorophenyl)methanol (1 .1 g, 48%) as a solid; TLC system: EtOAc/PE (1 :1 ), Rf: 0.3).
With palladium 10% on activated carbon; hydrogen; In tetrahydrofuran; methanol; at 20℃; for 2h; General procedure: To a solution of nitro compound (1.0mmol) in MeOH/THF (1:1) was added 10% Pd/C and charged with hydrogen gas. The mixture was stirred for 2hat room temperature. After completion, the mixture was filtered through Celite and the filtrate was concentrated in vacuo. The residue was puried by column chromatography on silica gel to afford the desired product.
  • 23
  • [ 660432-43-9 ]
  • [ 1402585-34-5 ]
  • 24
  • [ 660432-43-9 ]
  • [ 1402585-75-4 ]
  • 25
  • [ 660432-43-9 ]
  • [ 127349-56-8 ]
YieldReaction ConditionsOperation in experiment
85% With N-Bromosuccinimide; triphenylphosphine; In dichloromethane; at 0 - 23℃; for 2h; Step 2: To a cooled (0 C) and stirred solution of DCM (100 mL) containing <strong>[660432-43-9](2-fluoro-4-nitrophenyl)methanol</strong> (9 g, 52.6 mmol, 1 eq), triphenylphosphine (16.5 g, 63.1 mmol, 1 .2 eq) was added followed by addition of NBS (1 1 .24 g, 63.1 mmol, 1 .2 eq), the mixture was allowed to warm to RT and stirred for 2 h. The DCM was evaporated under reduced pressure and the residue was purified by CC using PE/EtOAc (9:1 ) as eluent to get l -(bromomethyl)-2-fluoro-4-nitrobenzene (10.50 g, 85%; TLC system: PE/EtOAc (7:3), Rf: 0.6).
  • 26
  • [ 660432-43-9 ]
  • [ 1402585-72-1 ]
  • 27
  • [ 660432-43-9 ]
  • [ 1402585-73-2 ]
 

Historical Records

Technical Information

Categories

Related Functional Groups of
[ 660432-43-9 ]

Fluorinated Building Blocks

Chemical Structure| 63878-73-9

A142266 [63878-73-9]

(2-Fluoro-5-nitrophenyl)methanol

Similarity: 0.98

Chemical Structure| 455-88-9

A163600 [455-88-9]

1-Fluoro-2-methyl-4-nitrobenzene

Similarity: 0.88

Chemical Structure| 20274-69-5

A324762 [20274-69-5]

4-Fluoro-3-nitrobenzyl alcohol

Similarity: 0.85

Chemical Structure| 170572-48-2

A132644 [170572-48-2]

1,3-Difluoro-2-methyl-5-nitrobenzene

Similarity: 0.85

Chemical Structure| 1736-85-2

A187625 [1736-85-2]

2-Fluoro-1,3-dimethyl-5-nitrobenzene

Similarity: 0.85

Aryls

Chemical Structure| 63878-73-9

A142266 [63878-73-9]

(2-Fluoro-5-nitrophenyl)methanol

Similarity: 0.98

Chemical Structure| 455-88-9

A163600 [455-88-9]

1-Fluoro-2-methyl-4-nitrobenzene

Similarity: 0.88

Chemical Structure| 20274-69-5

A324762 [20274-69-5]

4-Fluoro-3-nitrobenzyl alcohol

Similarity: 0.85

Chemical Structure| 170572-48-2

A132644 [170572-48-2]

1,3-Difluoro-2-methyl-5-nitrobenzene

Similarity: 0.85

Chemical Structure| 1736-85-2

A187625 [1736-85-2]

2-Fluoro-1,3-dimethyl-5-nitrobenzene

Similarity: 0.85

Alcohols

Chemical Structure| 63878-73-9

A142266 [63878-73-9]

(2-Fluoro-5-nitrophenyl)methanol

Similarity: 0.98

Chemical Structure| 20274-69-5

A324762 [20274-69-5]

4-Fluoro-3-nitrobenzyl alcohol

Similarity: 0.85

Chemical Structure| 946126-95-0

A151196 [946126-95-0]

(2-Fluoro-3-nitrophenyl)methanol

Similarity: 0.83

Chemical Structure| 1613329-94-4

A153123 [1613329-94-4]

(6-Fluoro-2-methyl-3-nitrophenyl)methanol

Similarity: 0.82

Chemical Structure| 1123172-89-3

A166916 [1123172-89-3]

(3,5-Difluoro-4-nitrophenyl)methanol

Similarity: 0.78

Nitroes

Chemical Structure| 63878-73-9

A142266 [63878-73-9]

(2-Fluoro-5-nitrophenyl)methanol

Similarity: 0.98

Chemical Structure| 455-88-9

A163600 [455-88-9]

1-Fluoro-2-methyl-4-nitrobenzene

Similarity: 0.88

Chemical Structure| 20274-69-5

A324762 [20274-69-5]

4-Fluoro-3-nitrobenzyl alcohol

Similarity: 0.85

Chemical Structure| 170572-48-2

A132644 [170572-48-2]

1,3-Difluoro-2-methyl-5-nitrobenzene

Similarity: 0.85

Chemical Structure| 1736-85-2

A187625 [1736-85-2]

2-Fluoro-1,3-dimethyl-5-nitrobenzene

Similarity: 0.85