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Chemical Structure| 65143-37-5 Chemical Structure| 65143-37-5

Structure of 65143-37-5

Chemical Structure| 65143-37-5

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Product Details of [ 65143-37-5 ]

CAS No. :65143-37-5
Formula : C11H12O3
M.W : 192.21
SMILES Code : CC(OCC(C1=CC=C(C)C=C1)=O)=O
MDL No. :MFCD00458047

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Application In Synthesis of [ 65143-37-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 65143-37-5 ]

[ 65143-37-5 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 65143-37-5 ]
  • [ 4079-54-3 ]
YieldReaction ConditionsOperation in experiment
6 g With hydrogenchloride; water; In ethanol;Reflux; General procedure: α-bromo-3’-chloroacetophenone (6a, 17.5 g, 75 mM) in ethanol (100 mL) was refluxed for 10 h with anhydrous sodium acetate (6.2 g, 76 mM). The mixture was diluted with water and the solid which separated was collected and recrystallized from ethyl acetate. Then the solid (2-(3-chlorophenyl)-2-oxoethyl acetate, 10.4 g, 49 mM, 65%) in ethanol (50 mL) and hydrochloric acid (50 mL of 1 M) was refluxed for 6 h. The mixture was diluted with water and was then extracted with ethyl acetate. The extract was dried (sodium sulfate) and concentrated to give 2a (6.8 g, 40 mM, 53%).
  • 2
  • [ 3240-34-4 ]
  • [ 720-94-5 ]
  • [ 65143-37-5 ]
 

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