Home Cart Sign in  
Chemical Structure| 6240-01-3 Chemical Structure| 6240-01-3

Structure of 6240-01-3

Chemical Structure| 6240-01-3

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 6240-01-3 ]

CAS No. :6240-01-3
Formula : C11H18ClNO2
M.W : 231.72
SMILES Code : O=C(C12CC3(N)CC(C2)CC(C3)C1)O.[H]Cl
MDL No. :MFCD01825827
InChI Key :CMUAQGBJDDHTPE-UHFFFAOYSA-N
Pubchem ID :365220

Safety of [ 6240-01-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 6240-01-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 6240-01-3 ]

[ 6240-01-3 ] Synthesis Path-Downstream   1~13

  • 2
  • [ 20866-48-2 ]
  • [ 6240-01-3 ]
  • [ 895167-08-5 ]
  • 3
  • [ 67-56-1 ]
  • [ 6240-01-3 ]
  • [ 80103-18-0 ]
  • 4
  • [ 6240-01-3 ]
  • [ 948045-15-6 ]
  • 5
  • [ 6240-01-3 ]
  • N,N'-bis(3-aminoadamantane-1-carboxylic acid)oxalamide [ No CAS ]
  • 7
  • [ 6240-01-3 ]
  • 3-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-adamantane-1-carboxylic acid [ No CAS ]
  • 8
  • [ 6240-01-3 ]
  • (S)-2-[(S)-2-({3-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-adamantane-1-carbonyl}-amino)-3-phenyl-propionylamino]-4-methylsulfanyl-butyric acid [ No CAS ]
  • 9
  • [ 6240-01-3 ]
  • [ 895167-19-8 ]
  • 10
  • [ 28920-43-6 ]
  • [ 6240-01-3 ]
  • [ 875211-10-2 ]
  • 11
  • [ 6240-01-3 ]
  • [ 501-53-1 ]
  • [ 10002-15-0 ]
  • 12
  • [ 6240-00-2 ]
  • [ 6240-01-3 ]
YieldReaction ConditionsOperation in experiment
78% With hydrogenchloride; water; at 95℃; for 144.0h; Step 2: 3-Amino-adamantane-1-carboxylic acid hydrochloride; To a 3-neck 5-L flask equipped with a reflux condenser, a mechanical stirrer and a temperature probe was added 3-acetylamino-adamantane-1-carboxylic acid (432 g, 1.82 mol), water (1.00 L) and concentrated hydrochloric acid (2.44 L), and the resulting mixture was heated at 95 C. for 6 days. During this time, solid material precipitated from the solution. After cooling at 0 C., the solids were filtered and washed with acetone. The solid was then dried under high vacuum at 50 C. for about 2 hours to afford 328 g (78%) of the title compound, 3-amino-adamantane-1-carboxylic acid hydrochloride, as a white solid. 1H NMR (300 MHz, DMSO-td6) delta 12.35 (br s, 1H), 8.27 (br s, 3H), 2.22-2.12 (m, 2H), 1.92-1.85 (m, 2H), 1.83-1.71 (ml 6H), 1.69-1.48 (m, 4H).
  • 13
  • [ 67-56-1 ]
  • [ 6240-01-3 ]
  • 3-aminoadamantane-1-carboxylic acid methyl ester hydrochloride [ No CAS ]
YieldReaction ConditionsOperation in experiment
92% With thionyl chloride; at 60℃; Step 3: 3-Amino-adamantane-1-carboxylic acid methyl ester hydrochloride; To a 3-neck 2-L flask equipped with a reflux condenser and a temperature probe was added <strong>[6240-01-3]3-amino-adamantane-1-carboxylic acid hydrochloride</strong> (100 g, 432 mmol) and methanol (1.0 L). To this solution was slowly added thionyl chloride (15.7 mL, 216 mmol) and the reaction was heated at 60 C. for 4 hours. Once cooled to room temperature, the crude reaction mixture was concentrated under reduced pressure to remove most of the methanol. Heptane (about 1-L) was then added and the mixture was once again concentrated under reduced pressure at which point a solid began to precipitate. This process was repeated three more times, then the solids were filtered off, washed with heptane and allowed to dry in open air to afford 97.2 g (92%) of the title compound, 3-amino-adamantane-1-carboxylic acid methyl ester hydrochloride, as a white solid. 1H NMR (300 MHz, CDCl3) delta 8.46 (br s, 3H), 3.65 (s, 3H), 2.33-2.24 (m, 2H), 2.23-2.16 (m, 2H), 2.11-1.95 (m, 4H), 1.94-1.78 (m, 4H), 1.75-1.62 (m,2H).
 

Historical Records

Technical Information

Categories

Related Functional Groups of
[ 6240-01-3 ]

Carboxylic Acids

Chemical Structure| 1245645-93-5

A192164 [1245645-93-5]

4-Aminoadamantane-1-carboxylic acid hydrochloride

Similarity: 0.94

Chemical Structure| 75667-94-6

A255274 [75667-94-6]

2-(3-Aminoadamantan-1-yl)acetic acid hydrochloride

Similarity: 0.94

Chemical Structure| 1057343-95-9

A859531 [1057343-95-9]

4-Aminoadamantane-1-carboxylic acid

Similarity: 0.91

Chemical Structure| 313683-55-5

A419338 [313683-55-5]

5-Aminocyclohexane-1,3-dicarboxylic acid

Similarity: 0.90

Chemical Structure| 16636-51-4

A179732 [16636-51-4]

cis-3-Aminocyclohexanecarboxylic acid

Similarity: 0.90