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Chemical Structure| 61704-26-5 Chemical Structure| 61704-26-5

Structure of 61704-26-5

Chemical Structure| 61704-26-5

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Product Details of [ 61704-26-5 ]

CAS No. :61704-26-5
Formula : C12H10ClN
M.W : 203.67
SMILES Code : CC1=CC=CC(C2=CC=C(Cl)C=C2)=N1
MDL No. :MFCD13152438
InChI Key :FDAGFEWXNZJOHU-UHFFFAOYSA-N
Pubchem ID :12367076

Safety of [ 61704-26-5 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 61704-26-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 61704-26-5 ]

[ 61704-26-5 ] Synthesis Path-Downstream   1~22

  • 1
  • [ 108715-11-3 ]
  • [ 61704-26-5 ]
  • 3
  • [ 15724-88-6 ]
  • [ 61704-26-5 ]
  • 4
  • [ 106-39-8 ]
  • [ 621685-64-1 ]
  • [ 61704-26-5 ]
  • 5
  • [ 621685-64-1 ]
  • [ 637-87-6 ]
  • [ 61704-26-5 ]
  • 6
  • [ 61704-26-5 ]
  • cis-2-(4-chlorophenyl)-6-methylpiperidine [ No CAS ]
  • 7
  • [ 61704-26-5 ]
  • 2-[4,4''-bis(6-methylpyridine-2-yl)-1,1';3',1"-terphenyl-5'-yl]-4,6-diphenyl-1,3,5-triazine [ No CAS ]
  • 8
  • [ 61704-26-5 ]
  • 4,6-diphenyl-2-[4-(6-methylpyridin-2-yl)-3'-(9-phenanthryl)-1,1'-biphenyl-5'-yl]-1,3,5triazine [ No CAS ]
  • 9
  • [ 61704-26-5 ]
  • 4,6-diphenyl-2-[5-(9-anthracenyl)-4'-(6-methylpyridin-2-yl)biphenyl-3-yl]-1,3,5-triazine [ No CAS ]
  • 10
  • [ 61704-26-5 ]
  • [ 73183-34-3 ]
  • 2-methyl-6-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyridine [ No CAS ]
YieldReaction ConditionsOperation in experiment
66% With tris-(dibenzylideneacetone)dipalladium(0); potassium acetate; XPhos; In 1,4-dioxane; at 100℃; for 18h;Inert atmosphere; Under an argon atmosphere, 2- (4-chlorophenyl) -6-methyl pyridine (27.0g, 0.13mol), 4,4,4 ', 4', 5,5,5 ', 5'- octamethyl -2, 2 '- bi-1,3,2-dioxaborolane (51.4 g, 0.20 mol), tris (dibenzylideneacetone) dipalladium (1.23 g, 1.3 mmol), 2-dicyclohexyl phosphino-2', 4 ', 6'-triisopropyl-biphenyl (1.29 g, 2.7 mmol), and potassium acetate (26.5 g, 0.27 mol) was suspended in 1,4-dioxane (520 mL), and heated to 0.89 C. . After stirring for 18 hours, allowed to cool. Was separated with chloroform, the organic layer was concentrated, the resulting crude product was purified by silica gel chromatography (developing solvent chloroform: hexane = 1: 1) to give the desired product 6-methyl-2- [4- ( 4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) phenyl] yellowish white crystals of pyridine (yield 25.8g, 66% yield).
  • 11
  • [ 5315-25-3 ]
  • [ 1679-18-1 ]
  • [ 61704-26-5 ]
YieldReaction ConditionsOperation in experiment
99% With tetrakis(triphenylphosphine) palladium(0); potassium carbonate; In 1,4-dioxane; water; at 70 - 90℃; for 18h;Inert atmosphere; A stream of argon, 2-bromo-6-methyl-pyridine (30.2g, 0.18mol), 4- chlorophenyl boronic acid (21.1g, 0.13mol), and tetrakis (triphenylphosphine) palladium (3.12g, 2.7 mmol) was suspended in 1,4-dioxane (340 mL), was heated to 70 C.. After dropping slowly 1.0M- aqueous potassium carbonate solution (405mL) to this, the temperature was raised to 90 , and the mixture was stirred for 18 hours. After cooling, was separated with chloroform, the organic layer was concentrated, the resulting crude product was purified by silica gel chromatography purification (developing solvent chloroform: hexane = 1 1 (by volume ratio, the same hereinafter)), to obtain the desired product of 2- (4-chlorophenyl) -6-methyl pyridine of yellow crystals (yield 27.0g, 99% yield).
  • 12
  • [ 109-99-9 ]
  • [ 61704-26-5 ]
  • 2-methyl-6-(4-(tetrahydrofuran-2-yl)phenyl)pyridine [ No CAS ]
  • 13
  • [ 1693-74-9 ]
  • [ 61704-26-5 ]
  • 2-methyl-6-(4-(tetrahydrofuran-2-yl-d<SUB>7</SUB>)phenyl)pyridine [ No CAS ]
  • 14
  • [ 61704-26-5 ]
  • 2-(4-iodophenyl)-6-methylpyridine [ No CAS ]
  • 15
  • [ 61704-26-5 ]
  • 2-methyl-6-(phenyl-4-d)pyridine [ No CAS ]
  • 16
  • [ 61704-26-5 ]
  • [ 13675-18-8 ]
  • (4-(6-methylpyridin-2-yl)phenyl)boronic acid [ No CAS ]
  • 17
  • [ 18368-63-3 ]
  • [ 1679-18-1 ]
  • [ 61704-26-5 ]
  • 18
  • [ 2867-59-6 ]
  • [ 3391-10-4 ]
  • [ 61704-26-5 ]
  • 19
  • [ 10412-98-3 ]
  • [ 1679-18-1 ]
  • [ 61704-26-5 ]
  • 20
  • [ 61704-26-5 ]
  • [ 149-73-5 ]
  • [ 101893-57-6 ]
  • C16H19NO3 [ No CAS ]
  • 22
  • [ 5315-25-3 ]
  • [ 637-87-6 ]
  • [ 61704-26-5 ]
 

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