Structure of 61704-26-5
*Storage: {[sel_prStorage]}
*Shipping: {[sel_prShipping]}
The BI-3802 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.
4.5
*For Research Use Only !
Change View
Size | Price | VIP Price | US Stock |
Global Stock |
In Stock | ||
{[ item.pr_size ]} |
Inquiry
{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price, item.pr_usd) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,1,item.pr_is_large_size_no_price, item.discount_usd) ]} {[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price, item.pr_usd) ]} |
Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]} | Inquiry {[ item.pr_usastock ]} In Stock Inquiry - | {[ item.pr_chinastock ]} {[ item.pr_remark ]} In Stock 1-2 weeks - Inquiry - | Login | - + | Inquiry |
Please Login or Create an Account to: See VIP prices and availability
US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days
1-2weeks
Inquiry
{[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}
{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price, item.pr_usd) ]}
{[ getRatePrice(item.pr_usd,1,item.mem_rate,item.pr_is_large_size_no_price, item.pr_usd) ]}
Inquiry
{[ getRatePrice(item.pr_usd,item.pr_rate,1,item.pr_is_large_size_no_price, item.vip_usd) ]}
{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price, item.pr_usd) ]}
{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price, item.pr_usd) ]}
In Stock
- +
Please Login or Create an Account to: See VIP prices and availability
US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
CAS No. : | 61704-26-5 |
Formula : | C12H10ClN |
M.W : | 203.67 |
SMILES Code : | CC1=CC=CC(C2=CC=C(Cl)C=C2)=N1 |
MDL No. : | MFCD13152438 |
InChI Key : | FDAGFEWXNZJOHU-UHFFFAOYSA-N |
Pubchem ID : | 12367076 |
GHS Pictogram: |
![]() |
Signal Word: | Warning |
Hazard Statements: | H302-H315-H319-H335 |
Precautionary Statements: | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501 |
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
66% | With tris-(dibenzylideneacetone)dipalladium(0); potassium acetate; XPhos; In 1,4-dioxane; at 100℃; for 18h;Inert atmosphere; | Under an argon atmosphere, 2- (4-chlorophenyl) -6-methyl pyridine (27.0g, 0.13mol), 4,4,4 ', 4', 5,5,5 ', 5'- octamethyl -2, 2 '- bi-1,3,2-dioxaborolane (51.4 g, 0.20 mol), tris (dibenzylideneacetone) dipalladium (1.23 g, 1.3 mmol), 2-dicyclohexyl phosphino-2', 4 ', 6'-triisopropyl-biphenyl (1.29 g, 2.7 mmol), and potassium acetate (26.5 g, 0.27 mol) was suspended in 1,4-dioxane (520 mL), and heated to 0.89 C. . After stirring for 18 hours, allowed to cool. Was separated with chloroform, the organic layer was concentrated, the resulting crude product was purified by silica gel chromatography (developing solvent chloroform: hexane = 1: 1) to give the desired product 6-methyl-2- [4- ( 4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) phenyl] yellowish white crystals of pyridine (yield 25.8g, 66% yield). |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
99% | With tetrakis(triphenylphosphine) palladium(0); potassium carbonate; In 1,4-dioxane; water; at 70 - 90℃; for 18h;Inert atmosphere; | A stream of argon, 2-bromo-6-methyl-pyridine (30.2g, 0.18mol), 4- chlorophenyl boronic acid (21.1g, 0.13mol), and tetrakis (triphenylphosphine) palladium (3.12g, 2.7 mmol) was suspended in 1,4-dioxane (340 mL), was heated to 70 C.. After dropping slowly 1.0M- aqueous potassium carbonate solution (405mL) to this, the temperature was raised to 90 , and the mixture was stirred for 18 hours. After cooling, was separated with chloroform, the organic layer was concentrated, the resulting crude product was purified by silica gel chromatography purification (developing solvent chloroform: hexane = 1 1 (by volume ratio, the same hereinafter)), to obtain the desired product of 2- (4-chlorophenyl) -6-methyl pyridine of yellow crystals (yield 27.0g, 99% yield). |