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Chemical Structure| 60563-13-5 Chemical Structure| 60563-13-5

Structure of 60563-13-5

Chemical Structure| 60563-13-5

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Product Details of [ 60563-13-5 ]

CAS No. :60563-13-5
Formula : C11H14O4
M.W : 210.23
SMILES Code : O=C(OCC)CC1=CC=C(O)C(OC)=C1
MDL No. :MFCD00009180
InChI Key :AWPMWZHWVKXADV-UHFFFAOYSA-N
Pubchem ID :108965

Safety of [ 60563-13-5 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P301+P312-P302+P352-P304+P340-P305+P351+P338

Application In Synthesis of [ 60563-13-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 60563-13-5 ]

[ 60563-13-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 327056-73-5 ]
  • [ 60563-13-5 ]
  • [ 1207544-60-2 ]
YieldReaction ConditionsOperation in experiment
With potassium carbonate; In 1-methyl-pyrrolidin-2-one; at 100℃; for 5h; To a solution of (4-hydroxy-3-methoxy-phenyl)-acetic acid ethyl ester (34, 2.0 g, 9.51 mmol) in NMP (10 mL) was added K2CO3 (3.94 g, 28.5 mmol) and 16 (1.48 g, 9.51 mmol). The reaction was heated at 100 C. for 5 h. The reaction mixture was cooled to RT and HCl (10%) was added. The mixture was extracted 3 times with EtOAc. The combined organics were washed with H2O and brine, dried over Na2SO4, filtered and evaporated in vacuo. The crude product was purified by SiO2 chromatography eluding with hexane/EtOAc to afford 35. Steps 2-4 were run as described for steps 2-4 of example 1, except in step 4, 4-amino-3-methyl-benzenesulfonamide was used in place of 4-amino-benzenesulfonamide which afforded I-51.
 

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