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Chemical Structure| 6000-59-5 Chemical Structure| 6000-59-5

Structure of 6000-59-5

Chemical Structure| 6000-59-5

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Product Details of [ 6000-59-5 ]

CAS No. :6000-59-5
Formula : C4H6O7
M.W : 166.09
SMILES Code : O=C(O)C=O.[H]O[H].O=C(O)C=O
MDL No. :N/A

Safety of [ 6000-59-5 ]

GHS Pictogram:
Signal Word:N/A
Hazard Statements:N/A
Precautionary Statements:N/A

Application In Synthesis of [ 6000-59-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 6000-59-5 ]

[ 6000-59-5 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 2932-65-2 ]
  • [ 6000-59-5 ]
  • [ 107549-80-4 ]
YieldReaction ConditionsOperation in experiment
With hydrazine hydrate; In ammonium hydroxide; (b) A mixture of <strong>[2932-65-2]4-n-propyl acetophenone</strong> (20.20 g) and glyoxylic acid monohydrate (11.51 g) was stirred and heated at 110 C. for 3 hours. The semi-solid obtained was dissolved in aqueous ammonia and filtered. The filtrate was treated with hydrazine hydrate (6.5 ml) and stirred under reflux with 4 hours to afford 6-(4-n-propylphenyl)pyridazin-3(2H)-one (11.96 g), m.p.180-82 C.
  • 2
  • [ 326-62-5 ]
  • [ 6000-59-5 ]
  • C10H5FNO2(1-)*K(1+) [ No CAS ]
  • 3
  • [ 6000-59-5 ]
  • [ 151414-76-5 ]
  • 2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-sulfonamide [ No CAS ]
  • 2-[2-(allyloxy)phenyl]-2-(2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-ylsulfonamido)acetic acid [ No CAS ]
YieldReaction ConditionsOperation in experiment
75% In nitromethane; at 60℃; for 12.0h; General procedure: A 10-mL screw-cap glass tube with PP-cap was charged with a magnetic stirring bar, 2,2,4,6,7-pentamethyl-2,3-dihydrobenzofuran-5-sulfonamide (1a; 68.0 mg, 0.25 mmol, 1.0 equiv), glyoxylic acid monohydrate (2; 30.0 mg, 0.33 mmol, 1.3 equiv), boronic acid 3 (0.5 mmol, 2.0 equiv), and nitromethane (1.5 mL, 0.17 M wrt sulfonamide) and firmly closed. The resulting mixture was stirred at 60 C for 12 h. After cooling to r.t., the mixture was diluted with acetone and filtered through a Celite/silica gel mixture and the filtrate was concentrated under reduced pressure. Purification of the crude residueby flash column chromatography afforded the product.
 

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