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Chemical Structure| 5876-69-7 Chemical Structure| 5876-69-7

Structure of 5876-69-7

Chemical Structure| 5876-69-7

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Product Details of [ 5876-69-7 ]

CAS No. :5876-69-7
Formula : C16H14O
M.W : 222.28
SMILES Code : CC(O)(C1=CC=CC=C1)C#CC2=CC=CC=C2

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Application In Synthesis of [ 5876-69-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 5876-69-7 ]

[ 5876-69-7 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 5876-69-7 ]
  • [ 1593-60-8 ]
  • [ 1415035-18-5 ]
YieldReaction ConditionsOperation in experiment
27% With iodine; In dichloromethane; water; at 25℃; for 2h; General procedure: To a solution of propargyl alcohol 1 (0.6 mmol) and N-tosyl hydroxylamine 2 (0.5 mmol) in wet DCM (5 mL) was added I2 (1.0 mmol) slowly at 25 C, and the reaction mixture was stirred at a shown temperature for an indicated period of time shown in text. Saturated aqueous Na2S2O3 was added to quench the reaction and the mixture was extracted with DCM. The organic layer was washed with brine and dried over Na2SO4, filtered and concentrated. The residue was purified flash column chromatography on silica gel with DCM/hexane as eluent to give 4 or 5.
  • 2
  • [ 5876-69-7 ]
  • [ 1520-44-1 ]
 

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