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Chemical Structure| 580-16-5 Chemical Structure| 580-16-5
Chemical Structure| 580-16-5

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6-Hydroxyquinoline is a quinoline derivative with antibacterial, antioxidant, and metal chelation properties, used in antibacterial agent research and potentially applicable in neuroprotective drug development.

4.5 *For Research Use Only !

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Product Details of 6-Hydroxyquinoline

CAS No. :580-16-5
Formula : C9H7NO
M.W : 145.16
SMILES Code : C1=C(O)C=CC2=NC=CC=C12
MDL No. :MFCD00047611
InChI Key :OVYWMEWYEJLIER-UHFFFAOYSA-N
Pubchem ID :11374

Safety of 6-Hydroxyquinoline

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of 6-Hydroxyquinoline

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 580-16-5 ]

[ 580-16-5 ] Synthesis Path-Downstream   1~5

  • 1
  • [ 580-16-5 ]
  • [ 3373-00-0 ]
YieldReaction ConditionsOperation in experiment
With hydrogen;palladium(IV) oxide; In methanol; The starting material was prepared as follows: 6-Hydroxyquinoline (1 g, 6.9 mmol) was dissolved in methanol and hydrogenated at 3 atmospheres pressure with platinum(IV) oxide (276 mg) over 24 hours. The catalyst was removed by filtration over a pad of celite and the solvent was evaporated. The solid was washed with ether to give 6-hydroxy-(1,2,3,4)-tetrahydroquinoline (698 mg, 68 %). 1H NMR Spectrum (DMSOd6) 1.75 (m, 2H); 2.60 (m, 2H); 3.05 (m, 2H); 4.90 (br s, 1H); 6.30 (m, 3H); 8.25 (br s, 1H)
  • 2
  • [ 580-16-5 ]
  • [ 7664-93-9 ]
  • [ 7732-18-5 ]
  • [ 3373-00-0 ]
  • 3
  • [ 580-16-5 ]
  • [ 7732-18-5 ]
  • KOH-solution [ No CAS ]
  • [ 3373-00-0 ]
 

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