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Chemical Structure| 55004-77-8 Chemical Structure| 55004-77-8
Chemical Structure| 55004-77-8

4-Hydroxy-6,7-dimethyl-2H-chromen-2-one

CAS No.: 55004-77-8

4.5 *For Research Use Only !

Cat. No.: A165795 Purity: 97%

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Product Details of [ 55004-77-8 ]

CAS No. :55004-77-8
Formula : C11H10O3
M.W : 190.20
SMILES Code : O=C1OC2=C(C=C(C)C(C)=C2)C(O)=C1
MDL No. :MFCD01457307

Safety of [ 55004-77-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Application In Synthesis of [ 55004-77-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 55004-77-8 ]

[ 55004-77-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 55004-77-8 ]
  • [ 363-52-0 ]
  • 10-fluoro-8,9-dihydroxy-2,3-dimethyl-6H-benzofuro[3,2-c]chromen-6-one [ No CAS ]
YieldReaction ConditionsOperation in experiment
70% With laccase; In aq. phosphate buffer; at 20℃; for 24h;pH 7.15;Enzymatic reaction; General procedure: The laccase (Suberase®, 2.0mL) was added to a mixture of the catechol (2.0mmol), coumarin (2.0mmol) and phosphate buffer (20.0mL, 0.10M, pH 7.15) in a 250mL round bottom flask stirred under air at rt. More laccase (2.0mL) was added after 2, 18 and 20h. The mixture was vigorously stirred under air until the substrates were consumed as judged by TLC. The mixture was extracted with EtOAc and washed two times with water (20.0mL). The organic phases were then combined and the solvent evaporated. The residue, a powder, was purified by washing with EtOAc or by flash chromatography or recrystallization. The recrystallization was accomplished from a combination of MeOH and EtOAc. Products were characterized by 1H NMR, 13C NMR, and MS.
 

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