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Chemical Structure| 4209-24-9 Chemical Structure| 4209-24-9
Chemical Structure| 4209-24-9

2-Chloro-1-(p-tolyl)ethanone

CAS No.: 4209-24-9

4.5 *For Research Use Only !

Cat. No.: A797936 Purity: 97%

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Product Details of [ 4209-24-9 ]

CAS No. :4209-24-9
Formula : C9H9ClO
M.W : 168.62
SMILES Code : CC1=CC=C(C(CCl)=O)C=C1
MDL No. :MFCD00972094
InChI Key :HGLJRZYKFVJSEE-UHFFFAOYSA-N
Pubchem ID :237805

Safety of [ 4209-24-9 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H315-H318-H335
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340+P312-P305+P351+P338+P310-P332+P313-P362-P403+P233-P405-P501
Class:8
UN#:1759
Packing Group:

Application In Synthesis of [ 4209-24-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 4209-24-9 ]

[ 4209-24-9 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 4209-24-9 ]
  • [ 4079-54-3 ]
  • 2
  • [ 4079-54-3 ]
  • [ 1025506-05-1 ]
  • C9H11NO4S [ No CAS ]
  • [ 4209-24-9 ]
  • 3
  • [ 30992-63-3 ]
  • [ 4209-24-9 ]
  • 2-(4-methylbenzoyl)-3-methyl-5-benzyloxybenzofuran [ No CAS ]
YieldReaction ConditionsOperation in experiment
73.9% With tetrabutylammomium bromide; potassium carbonate; In dichloromethane; water; for 12h;Reflux; <strong>[30992-63-3]2'-hydroxy-5'-benzyloxyacetophenone</strong> (6.05 g, 25 mmol),4'-Methyl-alpha-chloroacetophenone (25 mmol),Tetrabutylammonium bromide (4.03 g, 12.5 mmol) and 80 mL of dichloromethane were placed in 250 mL eggplant-shaped flasks.Then add 40mL of 30% potassium carbonate aqueous solution, stir and heat at reflux for 12h,TLC monitoring reaction is complete. The water layer was separated and the organic layer was washed three times with 100 mL of a 1 mol/L aqueous solution of hydrochloric acid.After washing with 100 mL of water again, the organic phase is decompressed to remove the solvent.The resulting solid was recrystallized from 60 mL of ethanol, and the precipitated crystals were collected, filtered, and dried.2-(4-methylbenzoyl)-3-methyl-6-benzyloxybenzofuran white flocculent solid 6.32 g,Yield 73.9%.
 

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