Purity | Size | Price | VIP Price | USA Stock *0-1 Day | Global Stock *5-7 Days | Quantity | |||||
{[ item.p_purity ]} | {[ item.pr_size ]} |
{[ getRatePrice(item.pr_usd, 1,1) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} |
{[ getRatePrice(item.pr_usd, 1,1) ]} | Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_usd,1,item.mem_rate) ]} | {[ item.pr_usastock ]} | Inquiry - | {[ item.pr_chinastock ]} | Inquiry - |
* Storage: {[proInfo.prStorage]}
CAS No. : | 40359-32-8 | MDL No. : | MFCD04227161 |
Formula : | C10H10O2 | Boiling Point : | - |
Linear Structure Formula : | - | InChI Key : | SEDRQGRABDFZKO-UHFFFAOYSA-N |
M.W : | 162.19 | Pubchem ID : | 2716612 |
Synonyms : |
|
Num. heavy atoms : | 12 |
Num. arom. heavy atoms : | 6 |
Fraction Csp3 : | 0.1 |
Num. rotatable bonds : | 4 |
Num. H-bond acceptors : | 2.0 |
Num. H-bond donors : | 0.0 |
Molar Refractivity : | 47.46 |
TPSA : | 26.3 Ų |
GI absorption : | High |
BBB permeant : | Yes |
P-gp substrate : | No |
CYP1A2 inhibitor : | Yes |
CYP2C19 inhibitor : | No |
CYP2C9 inhibitor : | No |
CYP2D6 inhibitor : | No |
CYP3A4 inhibitor : | No |
Log Kp (skin permeation) : | -5.62 cm/s |
Log Po/w (iLOGP) : | 2.07 |
Log Po/w (XLOGP3) : | 2.35 |
Log Po/w (WLOGP) : | 2.06 |
Log Po/w (MLOGP) : | 1.66 |
Log Po/w (SILICOS-IT) : | 2.66 |
Consensus Log Po/w : | 2.16 |
Lipinski : | 0.0 |
Ghose : | None |
Veber : | 0.0 |
Egan : | 0.0 |
Muegge : | 1.0 |
Bioavailability Score : | 0.55 |
Log S (ESOL) : | -2.43 |
Solubility : | 0.6 mg/ml ; 0.0037 mol/l |
Class : | Soluble |
Log S (Ali) : | -2.54 |
Solubility : | 0.465 mg/ml ; 0.00287 mol/l |
Class : | Soluble |
Log S (SILICOS-IT) : | -2.93 |
Solubility : | 0.192 mg/ml ; 0.00118 mol/l |
Class : | Soluble |
PAINS : | 0.0 alert |
Brenk : | 2.0 alert |
Leadlikeness : | 1.0 |
Synthetic accessibility : | 1.39 |
Signal Word: | Warning | Class: | N/A |
Precautionary Statements: | P261-P305+P351+P338 | UN#: | N/A |
Hazard Statements: | H302-H315-H319-H335 | Packing Group: | N/A |
GHS Pictogram: |
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
47% | at 180 - 182℃; Microwave irradiation | To a 3000 ml one neck, round bottom flask equipped with a condenser and thermometer was added allylether (7) (308 g) and tetrahydronaphthalene (300 mL). This reaction mixture was heated slowly up to 180-182° C. (ramped the temp. in 5-10 minutes, internal temperature) in a microwave (power: 1500 Watts) and was kept at this temperature while stirring for 7-8 h. At this stage the reaction mixture turned brown and the reaction mixture was cooled to room temperature followed by cooling at 0 to 5° C. for 30 minutes. The solid was filtered and dried to obtain off-white solid (3-hydroxy-2-allylbenzaldehyde, 8) 145.5 g (47percent). |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
33.3% | at 180 - 190℃; | Compound (2) (600 g) was added to decahydronaphthalene (1800 ml) and the stirred reaction mixture was heated to 180 to 190 0C. Stirring was continued till completion of the reaction as monitored by HPLC. After completion, the reaction mixture was cooled and acetonitrile (4200 ml) was added to it. The acetonitrile layer was separated, concentrated. Toluene was added to the residue. The resulting mass was cooled, filtered. Optional treatment of the solid thus obtained using mixture of ethyl acetate and cyclohexane gave compound (3). Yield: 200 g (33.3percent) |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
100% | With potassium carbonate; sodium iodide; In ethanol; for 3h;Reflux; | Example 1 . Preparation of 3-Allyloxybenzaldehyde; [0021] In a 1 L round bottomed flask equipped with mechanical stirrer, reflux condenser and thermometer were added 400 ml_ ethanol, 59.63 g of 3- hydroxybenzaldehyde (0.49 moles, 1 eq.), 7.3 g of sodium iodide (48 mmol, 0.1 eq.), 120.98 g of allyl bromide (0.59 moles, 1 .2eq.) and 101 .6 g of potassium carbonate (0.74 moles, 1 .25 eq.). The reaction mixture was heated to reflux and heating continued for three hours. Heating was then discontinued and the reaction was allowed to cool to room temperature. The mixture was then filtered through a Hyflosupercel pad and ethanol was removed by rotary evaporation. The residual oil was then taken up in 500 ml_ of MTBE and the organic phase washed sequentially with 10% aqueous sodium hydroxide, water and brine. After drying over sodium sulfate, filtration and rotary evaporation of solvent 79.7 g of a yellow oil of 3-allyloxybenzaldehyde (quantitative yield) was obtained. |
100% | With potassium carbonate; In ethanol; for 3h;Reflux; | Example 1 . Preparation of 3-Allyloxybenzaldehyde 3; [0016] In a 1 L round bottomed flask equipped with mechanical stirrer, reflux condenser and thermometer was added in sequence 400 mL ethanol, 59.63 g of 3-hydroxybenzaldehyde (0.49 moles, 1 eq.), 7.3 g of sodium iodide (48 mmol, 0.1 eq.), 120.98 g of allyl bromide (0.59 moles, 1 .2eq.) and 101 .6 g of potassium carbonate (0.74 moles, 1 .25 eq.). The reaction mixture was heated to reflux and heating continued for three hours. Heating was then discontinued and the reaction was allowed to cool to room temperature. The mixture was then filtered through a Hyflosupercel pad and ethanol was removed by rotary evaporation. The residual oil was then taken up in 500 mL of MTBE and the organic phase washed sequentially with 10% aqueous sodium hydroxide, water and brine. After drying over sodium sulfate, filtration and rotary evaporation of solvent 79.7 g of a yellow oil of 3-allyloxybenzaldehyde (quantitative yield) was obtained. |
100% | With potassium carbonate; sodium iodide; In ethanol; for 3h;Reflux; | In a 1 L round bottomed flask equipped with mechanical stirrer, reflux condenser and thermometer were added 400 mL ethanol, 59.63 g of 3-hydroxybenzaldehyde (0.49 moles,1 eq.), 7.3 g of sodium iodide (48 mmol, 0.1 eq.), 120.98 g of allyl bromide (0.59 moles,1.2 eq.) and 101.6 g of potassium carbonate (0.74 moles,1.25 eq.). The reaction mixture was heated to reflux and heating continued for three hours. Heating was then discontinued and the reaction was allowed to cool to room temperature. The mixture was then filtered through a Hyflosupercel pad and ethanol was removed by rotary evaporation. The residual oil was then taken up in 500 mL of MTBE and the organic phase washed sequentially with 10% aqueous sodium hydroxide, water and brine. After drying over sodium sulfate, filtration and rotary evaporation of solvent 79.7 g of a yellow oil of 3-allyloxybenzaldehyde (quantitative yield) was obtained. |
98% | With potassium carbonate; In N,N-dimethyl-formamide; at 20℃;Inert atmosphere; | General procedure: To a suspension ofphenol (16, 17, 22, and 23) (1 mmol, 1.0 equiv) and K2CO3(3 mmol, 3 equiv) in anhydrous DMF(5 mL) was added allylbromide (1.5 mmol, 1.5 equiv) dropwise under nitrogenatmosphere at room temperature. The mixture was stirred atroom temperature for 1 h. After completion of the reaction,water (10 mL) was added. The mixture was then extractedwith ether (2 × 30 mL), the combined organic layer waswashed with brine (2 × 30 mL), dried over anhydrousNa2SO4, filtered and the filtrate was concentrated in vacuo.The crude residue was purified by column chromatography (EtOAc/hexane = 1/8) to yield the allyl protected aldehyde(11, 18, 7, and 9). |
98% | With potassium carbonate; In N,N-dimethyl-formamide; at 20℃; for 1h;Inert atmosphere; | Phenol (16, 17, 22 and 23) (1 mmol, 1.0 eq.) And Allyl bromide (1.5 mmol, 1.5 eq.) Was added dropwise to a suspension of K2CO3 (3 mmol, 3 eq.) In anhydrous DMF (5 mL) under nitrogen atmosphere at room temperature. The mixture was stirred at room temperature for one hour. After completion of the reaction, water (10 ml) was added. The mixture was extracted with ether (2 x 30 mL) and the organic layer was washed with brine (2 x 30 mL), dried over anhydrous Na2SO4, filtered and the filtrate was concentrated in vacuo. The crude compound was purified by column chromatography (EtOAc / hexane = 1/8) to give aldehydes 11, 18, 7 and 9 protected with allyl groups. |
98% | With 18-crown-6 ether; potassium carbonate; potassium iodide; In acetonitrile; at 75℃; for 18h; | To a stirred solution of 3-hydroxybenzaldehyde (8.0 g, 65.6 mmol) in acetonitrile (80 mL) was added allylbromide (11.0 mL, 131 mmol), KI (1.09 g, 6.56 mmol), 18-crown-6 (864 mg, 3.26 mmol) and K2CO3 (26.4 g, 191 mmol) at rt, after which the solution was refluxed at 75 C for 18 h. The K2CO3 was filtered off and the solvent was removed under reduced pressure·H2O (100 mL) was added and the aqueous layer extracted with EtOAc (2 * 100 mL). The organic layer was separated, washed with brine (50 mL), dried (Na2SO4) and the solvent removed under reduced pressure to yield the title compound as an orange oil, which was used without further purification (10.5 g, 64.4 mmol, 98%). Rf = 0.38 (5% EtOAc in hexane). IR: lambdamax = 2861 (w, C-H), 1681 (s, C=O), 1598 (s, C=C), 1483 (m, C=C), 1457 (m, C=C). 1H NMR (400 MHz, CDCl3): deltaH = 9.92 (1H, s, H10), 7.37-7.44 (2H, m, H6 & H7), 7.36 (1H, dd, J = 2.0, 1.0 Hz, H9), 7.15 (1H, dt, J = 7.2, 2.4 Hz, H5), 5.96-6.09 (1H, ddt, J = 17.2, 10.5, 5.2 Hz, H2), 5.40 (1H, dq, J = 17.3, 1.5 Hz, H1t), 5.28 (1H, dq, J = 10.6, 1.4 Hz, H1c), 4.55 (2H, dt, J = 5.3, 1.4 Hz, H3). 13C NMR (101 MHz, CDCl3): deltaC = 192.0 (C10), 159.1 (C4), 137.8 (C8), 132.7 (C2), 130.1 (C6), 123.5 (C7), 122.0 (C5), 118.0 (C1), 113.1 (C9), 68.9 (C3) . HRMS (ESI+): m/z found [M+H]+ 163.0751, C10H11O2 required 163.0754. |
94.8% | With potassium carbonate; In N,N-dimethyl-formamide; at 25 - 45℃; | Meta hydroxy benzaldehyde (500 g) and potassium carbonate (679 g) were added to DMF (1000 ml). Allyl bromide (569.0 g) was gradually added to the reaction mixture, which was stirred at 25-45C. (0113) After completion of the reaction, water was added to the reaction mass followed by extraction with methyl tertiary butyl ether (MTBE). The organic layer was separated, washed with 1% sodium hydroxide solution (49 g NaOH in 490 ml water) to give compound (2). Yield: 630 g (94.8 %) |
92% | With sodium perborate; In water; at 20℃; for 8.5h;Green chemistry; | General procedure: To the 25 mL round bottomed flask containing 5 mL of water, were added beta-Naphthol (1d, 0.50 g, 1 eq.), sodium perborate (3, 0.214 g, 0.4 eq.), and allyl bromide (2, 0.462 g, 1.1 eq.) and reaction mixture was stirred at room temperature as given time. Progress of the reaction was monitored by TLC. After completion of the reaction (6h), the product was extracted with ethyl acetate (3x15 mL) and combined organic layers were dried over anhydrous sodium sulfate and concentrated under reduced pressure. The crude residue thus obtained was purified by silica gel column chromatography (100-200 mesh) to afford pure compound 4d. Similar procedure was adopted for the compounds 4a-c, and 4e-j. |
89% | With caesium carbonate; In N,N-dimethyl acetamide; ethyl acetate; | EXAMPLE 58A 3-(allyloxy)benzaldehyde 3-Hydroxybenzaldehyde (1.00 g, 8.19 mmol) and allyl bromide (0.780 mL, 9.01 mmol) in N,N-dimethylacetamide (35 mL) was treated with Cs2CO3 (4.01 g, 12.3 mmol) and allowed to stir at room temperature for 12 hours. The reaction mixture was diluted with diethyl ether (150 mL), washed with 1N HCl, saturated NaHCO3, brine, dried (MgSO4), filtered and the filtrate concentrated. The residue was purified by flash chromatography (silica gel, using 7% ethyl acetate/hexanes as eluent) to provide the title compound as a clear oil (1.19 g, 89%). 1H NMR (CDCl3, 300 MHz) delta 4.82 (m, 2H), 5.25-5.5.50 (m, 2H), 6.03 (m, 1H), 7.18-7.52 (m, 4H), 9.95 (s, 1H); MS (DCI+) 163 (M+H)+. |
83% | With potassium carbonate; In N,N-dimethyl-formamide; at 20℃; for 3h; | General procedure: To a solution of 3-hydroxybenzaldehyde 1a (81.9 mmol, 10.0 g) and K2CO3 (1.5 g) in DMF (100.0 mL) was added allyl bromide (7.8 mL) and the mixture was stirred for 3 h at rt. The reaction mixture was quenched with water (50 mL) and the organic phase was extracted into Et2O (3×100 mL), dried over Na2SO4 and the solvent removed at reduced pressure to give a yellow liquid 2a (11.0 g, 83%): FTIR (KBr) 3071, 2818, 1697 cm-1; 1H NMR (200 MHz): delta 9.91 (s, 1H), 7.41 (m, 3H), 7.17 (m, 1H), 6.04 (m, 1H), 5.41 (dd, J 16.0, 6.0 Hz, 1H), 5.30 (dd, J 10.0, 6.0 Hz, 1H), 4.58 (d, J 5.6 Hz, 2H); 13C NMR (50 MHz, CDCl3): delta 191.7, 159.1, 137.7, 132.8, 130.1, 123.6, 122.1, 118.0, 113.1, 68.9; MS(EI) m/z: 162 (M+, 100), 147 (47), 121 (94), 65 (81). |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
33.3% | In decalin; at 180 - 190℃; | Compound (2) (600 g) was added to decahydronaphthalene (1800 ml) and the stirred reaction mixture was heated to 180 to 190 0C. Stirring was continued till completion of the reaction as monitored by HPLC. After completion, the reaction mixture was cooled and acetonitrile (4200 ml) was added to it. The acetonitrile layer was separated, concentrated. Toluene was added to the residue. The resulting mass was cooled, filtered. Optional treatment of the solid thus obtained using mixture of ethyl acetate and cyclohexane gave compound (3). Yield: 200 g (33.3%) |
In decalin; at 217℃; for 7h;Inert atmosphere; | Example 2. Preparation of 2-allyl-3-hvdroxy-benzaldehyde; [0022] In a 500 ml three-necked Morton flask equipped with mechanical stirrer, thermometer and reflux condenser was added 100 g of <strong>[40359-32-8]3-allyloxybenzaldehyde</strong> (0.62 moles, 1 eq.) and 150 g of cis/trans decalin (1 .5 vol). The mixture was purged with nitrogen and then heated to a reflux temperature of 217C. The reaction was maintained at this reflux temperature for seven hours then cooled and added of 231 mL of toluene. The reaction mixture was then allowed to cool to room temperature. After stirring for 18 hours and further cooling to 0-5 C for 1 -2 hours, reaction mixture was filtered and the cake washed with 200 mL of heptane. The wet cake was stirred in 200 mL of heptane for 1 -2 hours at room temperature. After filtration and drying of the cake at 40 C, 54.27 g of crude 2-allyl-3-hydroxy-benzaldehyde were obtained. This represents a recovery of 82% of the available 2-allyl product produced by the Claisen rearrangement. | |
In decalin; at 217℃; for 7h;Inert atmosphere; | Example 2. Preparation of 2-allyl-3-hvdroxy-benzaldehyde 4; - 6 - 75907-27 (KB) [0017] In a 500 ml three-necked Morton flask equipped with mechanical stirrer, thermometer and reflux condenser was added 100 g of <strong>[40359-32-8]3-allyloxybenzaldehyde</strong> (0.62 moles, 1 eq.) and 150 g of cis/trans decalin (1 .5 vol). The mixture was purged with nitrogen and then heated to a reflux temperature of 217C. The reaction was maintained at this reflux temperature for seven hours then cooled and 231 mL of toluene was added.. The reaction mixture was then allowed to cool to room temperature. After stirring for 18 hours and further cooling to 0-5 C, reaction mixture was filtered and the cake washed with 200 mL of heptane. The wet cake was stirred in 200 mL of heptane for 1 -2 hours at room temperature. After filtration and drying of the cake at 40 C, 54.27 g of crude 2-allyl-3-hydroxy- benzaldehyde were obtained. This represents a recovery of 82% of the available 2-allyl product produced by the Claisen rearrangement. |
In decalin; at 217℃; for 7h;Inert atmosphere; | In a 500 ml three-necked Morton flask equipped with mechanical stirrer, thermometer and reflux condenser was added 100 g of <strong>[40359-32-8]3-allyloxybenzaldehyde</strong> (0.62 moles,1 eq.) and 150 g of cis/trans decalin (1.5 vol). The mixture was purged with nitrogen and then heated to a reflux temperature of 217 C. The reaction was maintained at this reflux temperature for seven hours then cooled and added of 231 mL of toluene. The reaction mixture was then allowed to cool to room temperature. After stirring for 18 hours and further cooling to 0-5 C. for 1-2 hours, reaction mixture was filtered and the cake washed with 200 mL of heptane. The wet cake was stirred in 200 mL of heptane for 1-2 hours at room temperature. After filtration and drying of the cake at 40 C., 54.27 g of crude 2-allyl-3-hydroxy-benzaldehyde were obtained. This represents a recovery of 82% of the available 2-allyl product produced by the Claisen rearrangement. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
47% | In tetralin; at 180 - 182℃;Microwave irradiation; | To a 3000 ml one neck, round bottom flask equipped with a condenser and thermometer was added allylether (7) (308 g) and tetrahydronaphthalene (300 mL). This reaction mixture was heated slowly up to 180-182° C. (ramped the temp. in 5-10 minutes, internal temperature) in a microwave (power: 1500 Watts) and was kept at this temperature while stirring for 7-8 h. At this stage the reaction mixture turned brown and the reaction mixture was cooled to room temperature followed by cooling at 0 to 5° C. for 30 minutes. The solid was filtered and dried to obtain off-white solid (3-hydroxy-2-allylbenzaldehyde, 8) 145.5 g (47percent). |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With sodium borohydrid; In methanol; acetic acid; | (B) To a solution of <strong>[40359-32-8]3-allyloxybenzaldehyde</strong> (7.2 g) in methanol (50 ml) at 0 C. was added sodium borohydride (1 g) in portions. The mixture was stirred for 30 minutes, evaporated dissolved in 5% acetic acid and extracted with diethyl ether (3*100 ml), washed with water (2*100 ml), and sodium bicarbonate (2*100 ml), dried (magnesium sulphate), filtered and evaporated to give 3-allyloxybenzyl alcohol (7.26 g). |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
78% | With potassium carbonate; In acetone; at 20℃; for 24h; | General procedure: A solution of 35a (260.5 mg, 1.308 mmol) in acetone (20 mL) was subsequently treated with potassium carbonate (903.8 mg, 6.539 mmol) and allylbromide (340 mu, 3.924 mmol). After stirring at RT for 24 h, the reaction was quenched with water (20 mL). The aqueous layer was extracted with dichloromethane (2 x 30 mL). The organics were combined, filtered through a phase separator and the volatiles were removed in vacuo. The residue was purified by silica gel chromatography using a 25 g Isolute cartridge eluted with a continuous gradient of iso- hexanes/ethyl acetate 1 :0 to 3:2 to afford the title compound (289.7 mg, 92%) as a colorless oil |
With potassium carbonate; In acetonitrile; for 2h;Reflux; | General procedure: To a solution of2-hydroxybenzaldehyde (15 g, 123 mmol, 1 equiv) and allylbromide (11.7 mL, 135 mmol, 1.1 equiv) in MeCN (250 mL) was added K2C03 (23.8 g, 172 mmol, 1.4 equiv). The yellow slurry was then heated to reflux. After 2 h, TLC indicated complete conversion. The now pale cream colored mixture was removed from heat and filtered. The filtrate was concentrated invacuo to provide 2-(allyloxy)benzaldehyde (19.15 g, 96%) as a yellow oil. 1H NMR (400 MHz, CDCl3) 8 10.64- 10.49 (m, 1H), 7.86 (dd, J = 7.7, 1.9 Hz, 1H), 7.61 -7.49(m, 1H), 7.11-6.90(m,2H),6.10(ddt,J= 17.3, 10.5,5.2Hz, 1H),5.47(dq,J=17.3, 1.5 Hz, 1H), 5.36 (dq, J = 10.5, 1.4 Hz, 1H), 4.68 (dt, J = 5.1, 1.6 Hz, 2H). |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With eosin y; In water; acetonitrile; at 20℃; for 4h;Irradiation; | General procedure: To a clean screw-top vial (25 mL) equipped with a stir bar was added Eosin Y (1 mol%), thioacetal 1 (1 equiv., 0.2 mmol), H2O(0.3 mL), and acetonitrile (1.7 mL). The reaction mixture was stirred vigorously for 2-8 h under the irradiation with 45W CFL bulbin open air. The crude reaction mixture was quenched by the addition of water (15 mL) and further extracted with ethyl acetate (3 15 mL). The combined organic layers was dried over anhydrous sodium sulfate, filtered, and concentrated under vacuum.The residue was further purified by column chromatography over silica gel using ethyl acetate and pet. ether as eluent to afford the desired product 2. |
Tags: 40359-32-8 synthesis path| 40359-32-8 SDS| 40359-32-8 COA| 40359-32-8 purity| 40359-32-8 application| 40359-32-8 NMR| 40359-32-8 COA| 40359-32-8 structure
[ 18075-40-6 ]
3-(Allyloxy)-4-methoxybenzaldehyde
Similarity: 0.92
[ 22280-95-1 ]
4-(Allyloxy)-3-methoxybenzaldehyde
Similarity: 0.92
[ 225939-36-6 ]
4-(Allyloxy)-3-ethoxybenzaldehyde
Similarity: 0.92
[ 42053-93-0 ]
4-(But-2-en-1-yloxy)benzaldehyde
Similarity: 0.92
[ 18075-40-6 ]
3-(Allyloxy)-4-methoxybenzaldehyde
Similarity: 0.92
[ 22280-95-1 ]
4-(Allyloxy)-3-methoxybenzaldehyde
Similarity: 0.92
[ 225939-36-6 ]
4-(Allyloxy)-3-ethoxybenzaldehyde
Similarity: 0.92
[ 42053-93-0 ]
4-(But-2-en-1-yloxy)benzaldehyde
Similarity: 0.92
[ 18075-40-6 ]
3-(Allyloxy)-4-methoxybenzaldehyde
Similarity: 0.92
[ 22280-95-1 ]
4-(Allyloxy)-3-methoxybenzaldehyde
Similarity: 0.92
[ 225939-36-6 ]
4-(Allyloxy)-3-ethoxybenzaldehyde
Similarity: 0.92
[ 42053-93-0 ]
4-(But-2-en-1-yloxy)benzaldehyde
Similarity: 0.92
[ 18075-40-6 ]
3-(Allyloxy)-4-methoxybenzaldehyde
Similarity: 0.92
[ 22280-95-1 ]
4-(Allyloxy)-3-methoxybenzaldehyde
Similarity: 0.92
[ 225939-36-6 ]
4-(Allyloxy)-3-ethoxybenzaldehyde
Similarity: 0.92
[ 42053-93-0 ]
4-(But-2-en-1-yloxy)benzaldehyde
Similarity: 0.92
Precautionary Statements-General | |
Code | Phrase |
P101 | If medical advice is needed,have product container or label at hand. |
P102 | Keep out of reach of children. |
P103 | Read label before use |
Prevention | |
Code | Phrase |
P201 | Obtain special instructions before use. |
P202 | Do not handle until all safety precautions have been read and understood. |
P210 | Keep away from heat/sparks/open flames/hot surfaces. - No smoking. |
P211 | Do not spray on an open flame or other ignition source. |
P220 | Keep/Store away from clothing/combustible materials. |
P221 | Take any precaution to avoid mixing with combustibles |
P222 | Do not allow contact with air. |
P223 | Keep away from any possible contact with water, because of violent reaction and possible flash fire. |
P230 | Keep wetted |
P231 | Handle under inert gas. |
P232 | Protect from moisture. |
P233 | Keep container tightly closed. |
P234 | Keep only in original container. |
P235 | Keep cool |
P240 | Ground/bond container and receiving equipment. |
P241 | Use explosion-proof electrical/ventilating/lighting/equipment. |
P242 | Use only non-sparking tools. |
P243 | Take precautionary measures against static discharge. |
P244 | Keep reduction valves free from grease and oil. |
P250 | Do not subject to grinding/shock/friction. |
P251 | Pressurized container: Do not pierce or burn, even after use. |
P260 | Do not breathe dust/fume/gas/mist/vapours/spray. |
P261 | Avoid breathing dust/fume/gas/mist/vapours/spray. |
P262 | Do not get in eyes, on skin, or on clothing. |
P263 | Avoid contact during pregnancy/while nursing. |
P264 | Wash hands thoroughly after handling. |
P265 | Wash skin thouroughly after handling. |
P270 | Do not eat, drink or smoke when using this product. |
P271 | Use only outdoors or in a well-ventilated area. |
P272 | Contaminated work clothing should not be allowed out of the workplace. |
P273 | Avoid release to the environment. |
P280 | Wear protective gloves/protective clothing/eye protection/face protection. |
P281 | Use personal protective equipment as required. |
P282 | Wear cold insulating gloves/face shield/eye protection. |
P283 | Wear fire/flame resistant/retardant clothing. |
P284 | Wear respiratory protection. |
P285 | In case of inadequate ventilation wear respiratory protection. |
P231 + P232 | Handle under inert gas. Protect from moisture. |
P235 + P410 | Keep cool. Protect from sunlight. |
Response | |
Code | Phrase |
P301 | IF SWALLOWED: |
P304 | IF INHALED: |
P305 | IF IN EYES: |
P306 | IF ON CLOTHING: |
P307 | IF exposed: |
P308 | IF exposed or concerned: |
P309 | IF exposed or if you feel unwell: |
P310 | Immediately call a POISON CENTER or doctor/physician. |
P311 | Call a POISON CENTER or doctor/physician. |
P312 | Call a POISON CENTER or doctor/physician if you feel unwell. |
P313 | Get medical advice/attention. |
P314 | Get medical advice/attention if you feel unwell. |
P315 | Get immediate medical advice/attention. |
P320 | |
P302 + P352 | IF ON SKIN: wash with plenty of soap and water. |
P321 | |
P322 | |
P330 | Rinse mouth. |
P331 | Do NOT induce vomiting. |
P332 | IF SKIN irritation occurs: |
P333 | If skin irritation or rash occurs: |
P334 | Immerse in cool water/wrap n wet bandages. |
P335 | Brush off loose particles from skin. |
P336 | Thaw frosted parts with lukewarm water. Do not rub affected area. |
P337 | If eye irritation persists: |
P338 | Remove contact lenses, if present and easy to do. Continue rinsing. |
P340 | Remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P341 | If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P342 | If experiencing respiratory symptoms: |
P350 | Gently wash with plenty of soap and water. |
P351 | Rinse cautiously with water for several minutes. |
P352 | Wash with plenty of soap and water. |
P353 | Rinse skin with water/shower. |
P360 | Rinse immediately contaminated clothing and skin with plenty of water before removing clothes. |
P361 | Remove/Take off immediately all contaminated clothing. |
P362 | Take off contaminated clothing and wash before reuse. |
P363 | Wash contaminated clothing before reuse. |
P370 | In case of fire: |
P371 | In case of major fire and large quantities: |
P372 | Explosion risk in case of fire. |
P373 | DO NOT fight fire when fire reaches explosives. |
P374 | Fight fire with normal precautions from a reasonable distance. |
P376 | Stop leak if safe to do so. Oxidising gases (section 2.4) 1 |
P377 | Leaking gas fire: Do not extinguish, unless leak can be stopped safely. |
P378 | |
P380 | Evacuate area. |
P381 | Eliminate all ignition sources if safe to do so. |
P390 | Absorb spillage to prevent material damage. |
P391 | Collect spillage. Hazardous to the aquatic environment |
P301 + P310 | IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
P301 + P312 | IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
P301 + P330 + P331 | IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. |
P302 + P334 | IF ON SKIN: Immerse in cool water/wrap in wet bandages. |
P302 + P350 | IF ON SKIN: Gently wash with plenty of soap and water. |
P303 + P361 + P353 | IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. |
P304 + P312 | IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell. |
P304 + P340 | IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. |
P304 + P341 | IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P305 + P351 + P338 | IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
P306 + P360 | IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes. |
P307 + P311 | IF exposed: call a POISON CENTER or doctor/physician. |
P308 + P313 | IF exposed or concerned: Get medical advice/attention. |
P309 + P311 | IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician. |
P332 + P313 | IF SKIN irritation occurs: Get medical advice/attention. |
P333 + P313 | IF SKIN irritation or rash occurs: Get medical advice/attention. |
P335 + P334 | Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages. |
P337 + P313 | IF eye irritation persists: Get medical advice/attention. |
P342 + P311 | IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. |
P370 + P376 | In case of fire: Stop leak if safe to Do so. |
P370 + P378 | In case of fire: |
P370 + P380 | In case of fire: Evacuate area. |
P370 + P380 + P375 | In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion. |
P371 + P380 + P375 | In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion. |
Storage | |
Code | Phrase |
P401 | |
P402 | Store in a dry place. |
P403 | Store in a well-ventilated place. |
P404 | Store in a closed container. |
P405 | Store locked up. |
P406 | Store in corrosive resistant/ container with a resistant inner liner. |
P407 | Maintain air gap between stacks/pallets. |
P410 | Protect from sunlight. |
P411 | |
P412 | Do not expose to temperatures exceeding 50 oC/ 122 oF. |
P413 | |
P420 | Store away from other materials. |
P422 | |
P402 + P404 | Store in a dry place. Store in a closed container. |
P403 + P233 | Store in a well-ventilated place. Keep container tightly closed. |
P403 + P235 | Store in a well-ventilated place. Keep cool. |
P410 + P403 | Protect from sunlight. Store in a well-ventilated place. |
P410 + P412 | Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF. |
P411 + P235 | Keep cool. |
Disposal | |
Code | Phrase |
P501 | Dispose of contents/container to ... |
P502 | Refer to manufacturer/supplier for information on recovery/recycling |
Physical hazards | |
Code | Phrase |
H200 | Unstable explosive |
H201 | Explosive; mass explosion hazard |
H202 | Explosive; severe projection hazard |
H203 | Explosive; fire, blast or projection hazard |
H204 | Fire or projection hazard |
H205 | May mass explode in fire |
H220 | Extremely flammable gas |
H221 | Flammable gas |
H222 | Extremely flammable aerosol |
H223 | Flammable aerosol |
H224 | Extremely flammable liquid and vapour |
H225 | Highly flammable liquid and vapour |
H226 | Flammable liquid and vapour |
H227 | Combustible liquid |
H228 | Flammable solid |
H229 | Pressurized container: may burst if heated |
H230 | May react explosively even in the absence of air |
H231 | May react explosively even in the absence of air at elevated pressure and/or temperature |
H240 | Heating may cause an explosion |
H241 | Heating may cause a fire or explosion |
H242 | Heating may cause a fire |
H250 | Catches fire spontaneously if exposed to air |
H251 | Self-heating; may catch fire |
H252 | Self-heating in large quantities; may catch fire |
H260 | In contact with water releases flammable gases which may ignite spontaneously |
H261 | In contact with water releases flammable gas |
H270 | May cause or intensify fire; oxidizer |
H271 | May cause fire or explosion; strong oxidizer |
H272 | May intensify fire; oxidizer |
H280 | Contains gas under pressure; may explode if heated |
H281 | Contains refrigerated gas; may cause cryogenic burns or injury |
H290 | May be corrosive to metals |
Health hazards | |
Code | Phrase |
H300 | Fatal if swallowed |
H301 | Toxic if swallowed |
H302 | Harmful if swallowed |
H303 | May be harmful if swallowed |
H304 | May be fatal if swallowed and enters airways |
H305 | May be harmful if swallowed and enters airways |
H310 | Fatal in contact with skin |
H311 | Toxic in contact with skin |
H312 | Harmful in contact with skin |
H313 | May be harmful in contact with skin |
H314 | Causes severe skin burns and eye damage |
H315 | Causes skin irritation |
H316 | Causes mild skin irritation |
H317 | May cause an allergic skin reaction |
H318 | Causes serious eye damage |
H319 | Causes serious eye irritation |
H320 | Causes eye irritation |
H330 | Fatal if inhaled |
H331 | Toxic if inhaled |
H332 | Harmful if inhaled |
H333 | May be harmful if inhaled |
H334 | May cause allergy or asthma symptoms or breathing difficulties if inhaled |
H335 | May cause respiratory irritation |
H336 | May cause drowsiness or dizziness |
H340 | May cause genetic defects |
H341 | Suspected of causing genetic defects |
H350 | May cause cancer |
H351 | Suspected of causing cancer |
H360 | May damage fertility or the unborn child |
H361 | Suspected of damaging fertility or the unborn child |
H361d | Suspected of damaging the unborn child |
H362 | May cause harm to breast-fed children |
H370 | Causes damage to organs |
H371 | May cause damage to organs |
H372 | Causes damage to organs through prolonged or repeated exposure |
H373 | May cause damage to organs through prolonged or repeated exposure |
Environmental hazards | |
Code | Phrase |
H400 | Very toxic to aquatic life |
H401 | Toxic to aquatic life |
H402 | Harmful to aquatic life |
H410 | Very toxic to aquatic life with long-lasting effects |
H411 | Toxic to aquatic life with long-lasting effects |
H412 | Harmful to aquatic life with long-lasting effects |
H413 | May cause long-lasting harmful effects to aquatic life |
H420 | Harms public health and the environment by destroying ozone in the upper atmosphere |
Sorry,this product has been discontinued.
Home
* Country/Region
* Quantity Required :
* Cat. No.:
* CAS No :
* Product Name :
* Additional Information :