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Chemical Structure| 40243-87-6 Chemical Structure| 40243-87-6
Chemical Structure| 40243-87-6

1-Ethenyl-3,5-dimethoxybenzene

CAS No.: 40243-87-6

4.5 *For Research Use Only !

Cat. No.: A1069631 Purity: 95%

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Product Details of [ 40243-87-6 ]

CAS No. :40243-87-6
Formula : C10H12O2
M.W : 164.20
SMILES Code : COC1=CC(OC)=CC(C=C)=C1
MDL No. :MFCD20384494

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Application In Synthesis of [ 40243-87-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 40243-87-6 ]

[ 40243-87-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 19591-17-4 ]
  • [ 40243-87-6 ]
  • [ 1130634-58-0 ]
YieldReaction ConditionsOperation in experiment
83% With palladium diacetate; trimethylamine; In N,N-dimethyl-formamide; at 120℃;Inert atmosphere; General procedure: In a dry neck flask, the appropriate N -(2-iodophenyl) acylamide ( 4 ) (1.0 equiv) was dissolved in dry DMF (12 mL) and stirred und er nitrogen. The solution was heated up to 120 C and refluxed for a few minutes. Palladium (II) acetate (0.1 equiv) was added, followed by trimethylamine (5.0 equiv) into the mixture. Then, the appropriate styrene ( 2 ) (1.2 equiv) was added to the reaction flask. The mixture was heated at 120 C under nitrogen until com- plete consumption of N -(2-iodophenyl) acylamide ( 4 ) (check via TLC). The reaction mixture was quenched with saturated ammo- nium chloride aqueous solution. It was then extracted with ethyl acetate (10 mL) and washed with plenty of distilled water (20 mL). The resulting organic fractions were combined, dried over an- hydrous sodium sulphate, and concentrated under reduced pres- sure to yield a crude product. Purification by column chromatogra- phy afforded the desired products ( 5a-5e ). The procedure for com- pounds 5a-5e is attached in Appendix [11] .
 

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