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Chemical Structure| 39785-37-0 Chemical Structure| 39785-37-0

Structure of 39785-37-0

Chemical Structure| 39785-37-0

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Product Details of [ 39785-37-0 ]

CAS No. :39785-37-0
Formula : C9H13NO
M.W : 151.21
SMILES Code : NC1=CC(C)=C(OC)C(C)=C1
MDL No. :MFCD01907075
InChI Key :HUPGZEYAAFYLSC-UHFFFAOYSA-N
Pubchem ID :4166097

Safety of [ 39785-37-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 39785-37-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 39785-37-0 ]

[ 39785-37-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 27741-65-7 ]
  • [ 39785-37-0 ]
  • ethyl 2-(1-(4-methoxy-3,5-dimethylphenylamino)cyclobutyl)acetate [ No CAS ]
YieldReaction ConditionsOperation in experiment
With hydrogenchloride; In 1,4-dioxane; toluene; for 72h;Heating / reflux; Step 4: Ethyl 2-(1-(4-methoxy-3,5-dimethylphenylamino)cyclobutyl)acetate To a solution of 4-methoxy-3,5-dimethylaniline (5 g) and <strong>[27741-65-7]ethyl 2-cyclobutylideneacetate</strong> (10 g) in 6 mL toluene, under nitrogen was added by syringe 1mL HCl (4M in dioxane). After refluxing the solution for 3 days, the mixture was concentrated, water was added, and the solution was extracted with ethyl acetate (3*20 mL). The combined organic layers were dried over Na2SO4 and the solvent was removed by evaporation. The crude compound was purified by column chromatography (10% ethyl acetate/hexane), giving ethyl 2-(1-(4-methoxy-3,5-dimethylphenylamino)-cyclobutyl)acetate (1 g) as a while solid. 1H-NMR (300 MHz, CDCl3) delta=6.21 (s, 2H), 4.10(q, 2H), 3.67 (s, 3H), 2.90 (s, 2H), 2.33 (m, 2H), 2.19 (m, 8H), 1.95 (m, 2H), 1.24 (t, J =6.9 Hz, 3H) ppm. MS: m/z 293 (100, M+H)+
 

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