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Chemical Structure| 352545-44-9 Chemical Structure| 352545-44-9

Structure of 352545-44-9

Chemical Structure| 352545-44-9

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Product Details of [ 352545-44-9 ]

CAS No. :352545-44-9
Formula : C6H16ClNO
M.W : 153.65
SMILES Code : CC(C)(C)[C@H](N)CO.[H]Cl
MDL No. :MFCD00077809

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Application In Synthesis of [ 352545-44-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 352545-44-9 ]

[ 352545-44-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 352545-44-9 ]
  • [ 24424-99-5 ]
  • [ 153645-26-2 ]
YieldReaction ConditionsOperation in experiment
87% With sodium hydroxide; In ethanol; water; at 40 - 50℃; A 100 ml four-neck flask was charged with tert-butyl ethylamine hydrochloride 10.0 g (1.0 eq), 30 ml of ethanol, and 10 ml of water. Sodium hydroxide 1. leq, adjust rho Eta = 8 ~ 9, warming to 40 ~ 50 C. Temperature control 40 ~ 50 C, drop B0C anhydride 1. leq, about 45min ~ 1.5h drops, heat lh. After the reaction of the raw materials is complete, the solvent is evaporated to dryness at 45-50C, and 100 ml of ethyl acetate is added, 30 ml After washing with x 3, the organic layer was dried by addition of 5.0 g of anhydrous sodium sulfate for 0.5 h, suction filtered, and the filtrate was dried by rotary evaporation at 45-50 C to obtain 12.3 g. 87%
 

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