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Chemical Structure| 32221-81-1 Chemical Structure| 32221-81-1

Structure of Glutamic acid sodium salt
CAS No.: 32221-81-1

Chemical Structure| 32221-81-1

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Synonyms: Monosodium glutamate

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Product Details of [ 32221-81-1 ]

CAS No. :32221-81-1
Formula : C5H8NNaO4
M.W : 169.11
SMILES Code : NC(CCC(O)=O)C([O-])=O.[Na+]
Synonyms :
Monosodium glutamate
MDL No. :N/A

Safety of [ 32221-81-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302+H312+H332-H315-H319
Precautionary Statements:P501-P261-P270-P271-P264-P280-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330-P302+P352+P312-P304+P340+P312

Application In Synthesis of [ 32221-81-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 32221-81-1 ]

[ 32221-81-1 ] Synthesis Path-Upstream   1~1

  • 1
  • [ 122-04-3 ]
  • [ 32221-81-1 ]
  • [ 6758-40-3 ]
YieldReaction ConditionsOperation in experiment
29.3 g
Stage #1: With sodium hydroxide In water
Stage #2: at 5℃;
2 Add 75g of water and 16.9g of sodium glutamate (0.1mol) to the reaction unit, adjust the pH to 8 with a 1mol/L sodium hydroxide solution with stirring, then cool to 5±1°C, slowly add dropwise The solution containing p-nitrobenzoyl chloride obtained in the step 1 was maintained at pH = 8 during the dropwise addition, and the reaction was completed until the temperature was 5 ± 1 ° C. After completion of the reaction, the pH was adjusted to 1 with dilute hydrochloric acid, crystallized, filtered, and the filter cake was washed with water and dried under reduced pressure to give 29.3 g of N-p-nitrobenzoyl-L-glutamic acid with a purity of 99.4percent ( HPLC), a two-step yield of 99.0percent based on p-nitrobenzoic acid.
References: [1] Patent: CN108147977, 2018, A, . Location in patent: Paragraph 0015; 0017; 0018; 0021; 0022; 0024.
 

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