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Chemical Structure| 258503-93-4 Chemical Structure| 258503-93-4

Structure of 258503-93-4

Chemical Structure| 258503-93-4

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Product Details of [ 258503-93-4 ]

CAS No. :258503-93-4
Formula : C9H5ClN2O
M.W : 192.60
SMILES Code : O=C(Cl)C1=CC=C2N=CC=NC2=C1
MDL No. :MFCD02682002

Safety of [ 258503-93-4 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H312-H332-H314
Precautionary Statements:P260-P280-P305+P351+P338-P310
Class:8
UN#:3261
Packing Group:

Application In Synthesis of [ 258503-93-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 258503-93-4 ]

[ 258503-93-4 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 117810-52-3 ]
  • [ 258503-93-4 ]
  • 2-(quinoxaline-6-carbonyl)-hexahydro-pyrrolo[1,2-<i>a</i>]pyrazin-6-one [ No CAS ]
  • 2
  • [ 107-83-5 ]
  • [ 23088-23-5 ]
  • [ 6925-00-4 ]
  • [ 258503-93-4 ]
YieldReaction ConditionsOperation in experiment
With hydrogenchloride; sodium hydroxide; In methanol; water; ethyl acetate; The 6-quinoxalinylcarbonyl chloride used as a starting material was prepared as follows: A 2N aqueous sodium hydroxide solution (7.95 ml) was added to a solution of <strong>[23088-23-5]methyl quinoxaline-6-carboxylate</strong> (1 g) in a mixture of methanol (30 ml) and water (5 ml) and the mixture was stirred at ambient temperature for 16 hours. The reaction mixture was evaporated and the residue was dissolved in water. The solution was acidified to pH3.5 by the addition of dilute aqueous hydrochloric acid and extracted with ethyl acetate. The organic extracts were evaporated and the residue was triturated under a mixture of ethyl acetate and isohexane. There was thus obtained quinoxaline-6-carboxylic acid a solid (0.5 g); NMR Spectrum: (DMSOd6) 8.16 (d, 1H), 8.28 (d, 1H), 8.59 (s, 1H), 9.02 (s, 2H).
 

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