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Type HazMat fee for 500 gram (Estimated)
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Chemical Structure| 24615-84-7 Chemical Structure| 24615-84-7

Structure of 24615-84-7

Chemical Structure| 24615-84-7

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Product Details of [ 24615-84-7 ]

CAS No. :24615-84-7
Formula : C6H8O4
M.W : 144.13
SMILES Code : C=CC(OCCC(O)=O)=O
MDL No. :MFCD00040709
InChI Key :CYUZOYPRAQASLN-UHFFFAOYSA-N
Pubchem ID :90558

Safety of [ 24615-84-7 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H314-H317
Precautionary Statements:P261-P264-P272-P280-P301+P330+P331-P303+P361+P353-P304+P340+P310-P305+P351+P338+P310-P333+P313-P363-P405-P501
Class:8
UN#:3265
Packing Group:

Application In Synthesis of [ 24615-84-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 24615-84-7 ]

[ 24615-84-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 24615-84-7 ]
  • [ 24835-08-3 ]
  • [ 1251836-30-2 ]
YieldReaction ConditionsOperation in experiment
3-(Acryloyloxy)propionic acid (5.7 g, 40.0 mmol), 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride (7.6 g, 40.0 mmol) and triethylamine (5.4 g, 53.0 mmol) were added to a solution of <strong>[24835-08-3]2-nitrobenzylamine hydrochloride</strong> (5.0 g, 26.5 mmol) in 20 ml of dichloromethane, followed by stirring at room temperature for 3 hours. After the reaction, chloroform and water were added, and the organic layer was separated, dried with saturated aqueous sodium chloride and over anhydrous sodium sulfate and concentrated under reduced pressure. The resulting residue was dissolved in 100 ml of ethanol, and sodium hydroxide (2.1 g, 53.0 mmol) and 50 ml of water were added, followed by stirring at room temperature for 2 hours. After the reaction, the reaction mixture was concentrated under reduced pressure and neutralized with concentrated hydrochloric acid, ethyl acetate was added, and the organic layer was separated, dried with saturated aqueous sodium chloride and over anhydrous sodium sulfate and concentrated under reduced pressure. The resulting residue was purified by silica gel column chromatography (n-hexane/ethyl acetate=9/1 to 0/1) to obtain 1.53 g of the desired product.
 

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