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Chemical Structure| 2459-05-4 Chemical Structure| 2459-05-4
Chemical Structure| 2459-05-4

Monoethyl fumarate

CAS No.: 2459-05-4

4.5 *For Research Use Only !

Cat. No.: A145377 Purity: 98%

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Product Details of Monoethyl fumarate

CAS No. :2459-05-4
Formula : C6H8O4
M.W : 144.13
SMILES Code : CCOC(=O)\C=C\C(O)=O
MDL No. :MFCD00002699

Safety of Monoethyl fumarate

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of Monoethyl fumarate

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 2459-05-4 ]

[ 2459-05-4 ] Synthesis Path-Downstream   1~8

  • 1
  • [ 2459-05-4 ]
  • [ 119072-55-8 ]
  • [ 134855-87-1 ]
  • [ 630-19-3 ]
  • C24H36N2O5 [ No CAS ]
  • 2
  • [ 2459-05-4 ]
  • [ 119072-55-8 ]
  • [ 134855-87-1 ]
  • [ 630-19-3 ]
  • (E)-ethyl 4-((1-(tert-butylamino)-3,3-dimethyl-1-oxobutan-2-yl)(1-(4-hydroxyphenyl)ethyl)amino)-4-oxobut-2-enoate [ No CAS ]
  • 3
  • [ 2459-05-4 ]
  • [ 65473-13-4 ]
  • trans-3-(N-methyl-1-naphthylmethylcarbamoyl)propenoic acid ethyl ester [ No CAS ]
  • 4
  • [ 2459-05-4 ]
  • [ 119072-55-8 ]
  • [ 109466-87-7 ]
  • [ 106-40-1 ]
  • [ 1070901-28-8 ]
  • 5
  • [ 20876-36-2 ]
  • [ 2459-05-4 ]
  • [ 1311143-61-9 ]
  • 6
  • [ 20876-36-2 ]
  • [ 2459-05-4 ]
  • [ 1311143-81-3 ]
  • 7
  • [ 2459-05-4 ]
  • C21H20N3O5Pol [ No CAS ]
  • [ 71989-31-6 ]
  • [ 108-24-7 ]
  • [ 198561-07-8 ]
  • [ 1312616-94-6 ]
YieldReaction ConditionsOperation in experiment
General procedure: All aza-peptidyl inhibitors and probes were synthesized by following the previously reported procedures 1, 2 with slight modifications. Fmoc protecting groups from Rink SS resin (0.75 mmol/g) were removed by treatment with 20percent piperidine in DMF for 15 min, followed by three washes with DMF. A 1.2 M solution of bromoacetic acid (10 eq) in NMP and DIC (10 eq) were added to the resin. The resin was shaken 1.5 hrs and washed three times. A solution of Mono-Fmoc protected hydrazide (3 eq) in NMP was added and shaken overnight. Resin loading was determined by Fmoc-quantification (0.2-0.3 mmol/g). A 0.5M solution of N-Fmoc-protected amino acid (3 eq.) and HOBt (3 eq.) in DMF and DIC (3 eq.) were added to the resin. The resin was shaken 1.5-2hrs. For each of the following steps, Fmoc-deprotection and coupling reactions were repeated as described above. Capping of N-terminal amine was achieved by shaking the resin with a 0.5 M solution of acetic anhydride (5 eq.) and DIEA (5 eq.) in DMF for 5 min.
  • 8
  • [ 2459-05-4 ]
  • [ 245660-15-5 ]
  • (E)-ethyl 4-((4-((tert-butyldimethylsilyl)oxy)butyl)amino)-4-oxobut-2-enoate [ No CAS ]
 

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