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Chemical Structure| 2265-94-3 Chemical Structure| 2265-94-3

Structure of 2265-94-3

Chemical Structure| 2265-94-3

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Product Details of [ 2265-94-3 ]

CAS No. :2265-94-3
Formula : C6H3F2NO2
M.W : 159.09
SMILES Code : O=[N+](C1=CC(F)=CC(F)=C1)[O-]
MDL No. :MFCD00012142
InChI Key :AUQBBDWDLJSKMI-UHFFFAOYSA-N
Pubchem ID :75272

Safety of [ 2265-94-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H227-H315-H319-H335
Precautionary Statements:P305+P351+P338

Application In Synthesis of [ 2265-94-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 2265-94-3 ]

[ 2265-94-3 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 109-00-2 ]
  • [ 2265-94-3 ]
  • [ 803700-29-0 ]
YieldReaction ConditionsOperation in experiment
With potassium carbonate; In N,N-dimethyl-formamide; at 100℃; for 6.0h; To a solution of 3-hydroxypyridine (3.25 g) in dimethylformamide (75 ml), 6.75 g of potassium carbonate and 5.0 g of l,3-difluoro-5-nitrobenzene were added, and the reaction solution was stirred at 100C for 6 hours. The reaction solution was cooled, thereafter diluted with a saturated aqueous ammonium chloride solution, and extracted with ethyl acetate. The combined organic layers were washed with water and a saturated saline solution and dried over anhydrous sodium sulfate. The solvent was distilled off under reduced pressure, and the resultant residue was purified by silica gel chromatography to yield the title compound as a yellow oil. ' H-NMR(CDCl3 )delta:7.05(lH,dt,J=8.6,2.4Hz),7.39-7.45(2H,m),7.62-7.64(lH,m),7.70(lH,dt,J=8.2,2.2H z),8.49(lH,d,J=2.2Hz),8.55(lH,dd,J=4.4,2.2Hz). ESI-MS Found:m/z 235.1[M+H]+
 

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