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Chemical Structure| 22118-12-3 Chemical Structure| 22118-12-3

Structure of 22118-12-3

Chemical Structure| 22118-12-3

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Product Details of [ 22118-12-3 ]

CAS No. :22118-12-3
Formula : C4H6BrClO
M.W : 185.45
SMILES Code : O=C(Cl)C(Br)CC
MDL No. :MFCD00055269
InChI Key :DROZQELYZZXYSX-UHFFFAOYSA-N
Pubchem ID :90734

Safety of [ 22118-12-3 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H225-H290-H314
Precautionary Statements:P210-P233-P234-P240-P241+P242+P243-P260-P264-P280-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P370+P378-P390-P403+P235-P405-P406-P501
Class:8(3)
UN#:2920
Packing Group:

Application In Synthesis of [ 22118-12-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 22118-12-3 ]

[ 22118-12-3 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 22118-12-3 ]
  • [ 6638-05-7 ]
  • [ 256456-36-7 ]
  • 2
  • [ 22118-12-3 ]
  • [ 436-77-1 ]
  • 7-O-(2-bromide butyryl)-fangchinoline [ No CAS ]
YieldReaction ConditionsOperation in experiment
75% General procedure: Fangchinoline (100 mg, 0.16 mmol) was dissolved in 8 mL of CH2Cl2. The mixture was cooled to 0 C under N2. Pyridine (25 mg, 0.32 mmol) was added to the mixture. The solution was stirred for 1 h and various types of acyl chlorides (0.24 mmol, in 2 mL of CH2Cl2) were added dropwise over 10 min. The mixture was stirred for 1 h at 0 C and was stirred another hour at room temperature. The mixture was washed with water, dried over anhydrous Na2SO4 and filtered. After being concentrated under vacuum, the residue was purified by flash chromatography on silica gel using CH2Cl2/CH3OH as eluant to afford the desired products 6a-6p.
 

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Related Functional Groups of
[ 22118-12-3 ]

Bromides

Chemical Structure| 7148-74-5

A834224 [7148-74-5]

2-Bromopropionylchloride

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Acyl Chlorides

Chemical Structure| 7148-74-5

A834224 [7148-74-5]

2-Bromopropionylchloride

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