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Type HazMat fee for 500 gram (Estimated)
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Chemical Structure| 21900-62-9 Chemical Structure| 21900-62-9

Structure of 21900-62-9

Chemical Structure| 21900-62-9

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Product Details of [ 21900-62-9 ]

CAS No. :21900-62-9
Formula : C10H11ClO
M.W : 182.65
SMILES Code : O=C(Cl)C1=CC=C(C(C)C)C=C1
MDL No. :MFCD03424703
InChI Key :LBSYWDTVBUZMCM-UHFFFAOYSA-N
Pubchem ID :2759486

Safety of [ 21900-62-9 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H314-H332
Precautionary Statements:P260-P261-P264-P270-P271-P280-P301+P312-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P312-P321-P330-P363-P405-P501
Class:8
UN#:1760
Packing Group:

Application In Synthesis of [ 21900-62-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 21900-62-9 ]

[ 21900-62-9 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 21900-62-9 ]
  • [ 13659-23-9 ]
  • [ 74-88-4 ]
  • C17H16BrClO2 [ No CAS ]
  • 2
  • [ 21900-62-9 ]
  • [ 369-26-6 ]
  • methyl 4-fluoro-3-([4-(1-methylethyl)phenyl]carbonyl}amino)benzoate [ No CAS ]
YieldReaction ConditionsOperation in experiment
72% With pyridine; In dichloromethane; at 20℃; for 1h; To a solution of <strong>[369-26-6]methyl 3-amino-4-fluorobenzoate</strong> (100 mg, 0.591 mmol) in DCM (3 ml) was added 4-(l-methylethyl)benzoyl chloride (162 mg, 0.887 mmol) and pyridine (96 mu, 1.18 mmol) at room temperature. The mixture was stirred for 1 h. 1 M HC1 and DCM were added and the phases were separated, the organic phase collected and the volatiles were removed in vacuo. The compound was purified by flash column chromatography. Yield: 135 mg (72percent); white solid. MS (ESI+) m/z 316 [M+H]+. HPLC purity: 99percent.
 

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