Home Cart Sign in  
Chemical Structure| 20808-12-2 Chemical Structure| 20808-12-2

Structure of Fluoromethyl phenyl sulfone
CAS No.: 20808-12-2

Chemical Structure| 20808-12-2

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 20808-12-2 ]

CAS No. :20808-12-2
Formula : C7H7FO2S
M.W : 174.19
SMILES Code : O=S(C1=CC=CC=C1)(CF)=O
MDL No. :MFCD00191650
InChI Key :DENHPZASLKBBHA-UHFFFAOYSA-N
Pubchem ID :2759036

Safety of [ 20808-12-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 20808-12-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 20808-12-2 ]

[ 20808-12-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 20808-12-2 ]
  • [ 167298-40-0 ]
  • [ 1443930-14-0 ]
  • C17H24FNO5S [ No CAS ]
YieldReaction ConditionsOperation in experiment
330 mg; 102 mg With lithium hexamethyldisilazane; at -78 - 20℃; Example 25 A THF (17 mL) solution of (fluoromethylsulfonyl)benzene (852.4 mg, 4.9 mmol) was treated drop-wise with 1 M LiHMDS/THF (4.8 mL, 4.8 mmol) at -78 C followed by the drop-wise addition of a THF (3mL) solution of compound 11 (440 mg, 2.21 mmol). Initial evaluation of reaction progress by silica gel TLC after 67 min. indicated significant 1 remained. The reaction was warmed slightly before recooling to -78 C and adding additional LiHMDS (2.4 mL) solution drop-wise and allowing the reaction bath to warm to ambient temperature, at which time the reaction had consumed all of compound 1 . After the addition of 1 mL of HOAc and an approximately equal volume of THF the reaction was evaporated (in vacuo) at 30 C before partitioning between DCM and water. Combined DCM phases after an extraction of the initial aqueous phase with DCM were washed with brine, dried Na2SO4, and evaporated. Isolation and purification of compound 2 was accomplished via flash chromatography (silica gel, DCM/ethyl acetate) affording 330 mg. An alternate isomer (presumed trans) was further eluted affording 102 mg. H and 9F spectra (CDCI3) were consistent with expectations.
 

Historical Records

Technical Information

Categories

Related Functional Groups of
[ 20808-12-2 ]

Fluorinated Building Blocks

Chemical Structure| 426-58-4

A506874 [426-58-4]

Phenyl Trifluoromethyl Sulfone

Similarity: 0.92

Chemical Structure| 24906-77-2

A442561 [24906-77-2]

4-((Difluoromethyl)sulfonyl)aniline

Similarity: 0.82

Chemical Structure| 383-10-8

A191507 [383-10-8]

1-Methyl-4-((trifluoromethyl)sulfonyl)benzene

Similarity: 0.82

Aryls

Chemical Structure| 426-58-4

A506874 [426-58-4]

Phenyl Trifluoromethyl Sulfone

Similarity: 0.92

Chemical Structure| 24906-77-2

A442561 [24906-77-2]

4-((Difluoromethyl)sulfonyl)aniline

Similarity: 0.82

Chemical Structure| 383-10-8

A191507 [383-10-8]

1-Methyl-4-((trifluoromethyl)sulfonyl)benzene

Similarity: 0.82

Sulfones

Chemical Structure| 426-58-4

A506874 [426-58-4]

Phenyl Trifluoromethyl Sulfone

Similarity: 0.92

Chemical Structure| 24906-77-2

A442561 [24906-77-2]

4-((Difluoromethyl)sulfonyl)aniline

Similarity: 0.82

Chemical Structure| 383-10-8

A191507 [383-10-8]

1-Methyl-4-((trifluoromethyl)sulfonyl)benzene

Similarity: 0.82