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Chemical Structure| 1917-66-4 Chemical Structure| 1917-66-4

Structure of 1917-66-4

Chemical Structure| 1917-66-4

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Product Details of [ 1917-66-4 ]

CAS No. :1917-66-4
Formula : C9H12O3
M.W : 168.19
SMILES Code : O=CC1=CC=C(COCCC)O1
MDL No. :MFCD06496510

Safety of [ 1917-66-4 ]

Application In Synthesis of [ 1917-66-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 1917-66-4 ]
  • Downstream synthetic route of [ 1917-66-4 ]

[ 1917-66-4 ] Synthesis Path-Upstream   1~4

  • 1
  • [ 71-23-8 ]
  • [ 57-50-1 ]
  • [ 1917-66-4 ]
  • [ 645-67-0 ]
YieldReaction ConditionsOperation in experiment
65 %Spectr. at 180℃; for 40 h; 1.8 g of sucrose,0.361 g of SnCl4, 0. 058 g of BF3?, 20? Of n-propanol were added to 50 mLStainless steel-lined reactor with Teflon,Heated to 180 ° C,The reaction was carried out at that temperature for 40 h. Filtration,To remove unreacted sucrose and other insoluble impurities,The solvent was removed by rotary evaporation,2 mL H20 was added and the organic phase was extracted with methyl isobutyl ketone,The resulting organic phase was rotary evaporated to a high purity furan derivative,The isolated yield was 89percent. The qualitative analysis of the reaction products was carried out by gas chromatography-mass spectrometry (GC-MS)And with the standard material (HMF,Propoxyl methyl furfural and propyl propionate)The retention times in gas chromatography (GC) were compared and confirmed. Quantitative analysis of the yield distribution of different furan derivatives was determined by 4 NMR,The product distribution results are:5-propoxymethylfurfural was 65percent,HMF was 0percent and propyl levulinate was 35percent.
References: [1] Patent: CN103467418, 2016, B, . Location in patent: Paragraph 0021.
  • 2
  • [ 71-23-8 ]
  • [ 57-50-1 ]
  • [ 67-47-0 ]
  • [ 1917-66-4 ]
  • [ 645-67-0 ]
YieldReaction ConditionsOperation in experiment
72 %Spectr. at 100℃; for 10 h; 1.8 g of sucrose,0.271 g of GeCl4, 0.091 g of BBr3, and 20 mL of n-propanol were added to 50 mL of a polyTetrafluoroethylene-lined stainless steel reactor,Heated to l00 ° C,The reaction was carried out at that temperature for 10 h. Filtration,To remove unreacted sucrose and other insoluble impurities,The solvent was removed by rotary evaporation,2 mL H20 was added and the organic phase was extracted with methyl isobutyl ketone,The resulting organic phase was rotary evaporated to a high purity furan derivative,The isolated yield was 83percent. The qualitative analysis of the reaction products was carried out by gas chromatography-mass spectrometry (GC-MS)And with the standard material (HMF,5-propoxymethylfurfural and propyl propionate) in gas chromatography (GC) were compared and confirmed. Quantitative analysis of the yield distribution of different furan derivatives was confirmed by 1H NMR,The product distribution results are:5-propoxymethylfurfural was 72percent, HMF was 9percentPropyl propionate was 19percent
References: [1] Patent: CN103467418, 2016, B, . Location in patent: Paragraph 0020.
  • 3
  • [ 71-23-8 ]
  • [ 57-48-7 ]
  • [ 1917-66-4 ]
  • [ 111-43-3 ]
  • [ 110-74-7 ]
  • [ 645-67-0 ]
References: [1] Green Chemistry, 2013, vol. 15, # 10, p. 2895 - 2903.
  • 4
  • [ 71-23-8 ]
  • [ 6347-01-9 ]
  • [ 1917-66-4 ]
  • [ 645-67-0 ]
References: [1] Green Chemistry, 2014, vol. 16, # 2, p. 785 - 791.
 

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