Home Cart Sign in  
Chemical Structure| 18992-80-8 Chemical Structure| 18992-80-8

Structure of 18992-80-8

Chemical Structure| 18992-80-8

3-Dimethylaminoacetophenone

CAS No.: 18992-80-8

4.5 *For Research Use Only !

Cat. No.: A299406 Purity: 98%

Change View

Size Price

US Stock

Global Stock

In Stock
100mg łÇď¶ÊÊ Inquiry Inquiry
250mg łËͶÊÊ Inquiry Inquiry
1g łÿʶÊÊ Inquiry Inquiry
5g łÇÿʶÊÊ Inquiry Inquiry

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • 100mg

    łÇď¶ÊÊ

  • 250mg

    łËͶÊÊ

  • 1g

    łÿʶÊÊ

  • 5g

    łÇÿʶÊÊ

In Stock

- +

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 18992-80-8 ]

CAS No. :18992-80-8
Formula : C10H13NO
M.W : 163.22
SMILES Code : CC(C1=CC=CC(N(C)C)=C1)=O
MDL No. :MFCD00059343

Safety of [ 18992-80-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 18992-80-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 18992-80-8 ]

[ 18992-80-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 179543-88-5 ]
  • [ 18992-80-8 ]
  • [ 95-92-1 ]
  • [ 858598-00-2 ]
YieldReaction ConditionsOperation in experiment
90% [Referential Example 15] 5-(3-Dimethylaminophenyl)-1-(6-methoxy-3-pyridyl)-1H-pyrazole-3-c arboxylic acid; [Show Image] 1) Ethyl 5-(3-dimethylaminophenyl)-1-(6-methoxy-3-pyridyl)-1H-pyrazole-3-carboxylate; A solution of 1-(3-dimethylaminophenyl)-1-ethanone (1.63 g) in ethanol (20 ml) and diethyl oxalate (3.10 ml) were added to a solution of sodium ethoxide (1.63 g) in ethanol (20 ml), and the mixture was stirred at room temperature for 1 hour. To the reaction liquid was added the <strong>[179543-88-5]5-hydrazino-2-methoxypyridine hydrochloride</strong> (2.52 g) of Referential Example 1, and the mixture was heated under reflux for 14.5hours. After cooling with air, the reaction solvent was evaporated under reduced pressure. To the residue were added ethyl acetate and saturated aqueous sodium bicarbonate, and the phases were separated, and the organic layer was dried over anhydrous sodium sulfate. After filtration, the solvent was evaporated under reduced pressure, and the residue was purified by column chromatography on silica gel (ethyl acetate-hexane) to give ethyl 5-(3-dimethylaminophenyl)-1-(6-methoxy-3-pyridyl)-1H-pyrazole-3-c arboxylate (3.30 g, 90%) as an oily product. 1H-NMR (400 MHz, CDCl3)delta: 1.43 (3H, t, J = 7.1 Hz), 2.87 (6H, s), 3.93 (3H, s), 4.46 (2H, q, J = 7.1 Hz), 6.50 (1H, d, J = 7.6 Hz), 6.54-6.55 (1H, m), 6.69 (1H, dd, J = 8.3, 2.4 Hz), 6.73 (1H, d, J = 8.8 Hz), 7.03 (1H, s), 7.16 (1H, dd, J = 8.1, 7.8 Hz), 7.59 (1H, dd, J = 8.8, 2.7 Hz), 8.15 (1H, d, J = 2.7 Hz). ESI-MSm/z: 367 (M+H)+.
 

Historical Records

Technical Information

Categories