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Chemical Structure| 1599440-33-1 Chemical Structure| 1599440-33-1
Chemical Structure| 1599440-33-1

Dxd

CAS No.: 1599440-33-1

Dxd (Exatecan derivative for ADC) is a potent DNA topoisomerase I inhibitor (IC50 = 0.31 µM) and serves as the payload for the HER2-targeting antibody-drug conjugate ADC (DS-8201a).

Synonyms: Exatecan derivative for ADC

4.5 *For Research Use Only !

Cat. No.: A1177236 Purity: 98%

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Product Details of [ Dxd ]

CAS No. :1599440-33-1
Formula : C26H24FN3O6
M.W : 493.48
SMILES Code : O=C1C2=C([C@@](O)(CC)C(OC2)=O)C=C3C4=NC5=CC(F)=C(C)C6=C5C([C@H](CC6)NC(CO)=O)=C4CN13
Synonyms :
Exatecan derivative for ADC
MDL No. :MFCD31657444
InChI Key :PLXLYXLUCNZSAA-QLXKLKPCSA-N
Pubchem ID :117888634

Safety of [ Dxd ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301
Precautionary Statements:P501-P270-P264-P301+P310+P330-P405
Class:6.1
UN#:2811
Packing Group:

Related Pathways of [ Dxd ]

DNA

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.03mL

0.41mL

0.20mL

10.13mL

2.03mL

1.01mL

20.26mL

4.05mL

2.03mL

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