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Chemical Structure| 150281-46-2 Chemical Structure| 150281-46-2

Structure of 150281-46-2

Chemical Structure| 150281-46-2

3-(Pyrrolidin-3-yl)pyridine

CAS No.: 150281-46-2

4.5 *For Research Use Only !

Cat. No.: A652986 Purity: 95%

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Product Details of [ 150281-46-2 ]

CAS No. :150281-46-2
Formula : C9H12N2
M.W : 148.21
SMILES Code : C1(C2CNCC2)=CC=CN=C1
MDL No. :MFCD02089474

Safety of [ 150281-46-2 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H314
Precautionary Statements:P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P321-P363-P405-P501
Class:8
UN#:1759
Packing Group:

Application In Synthesis of [ 150281-46-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 150281-46-2 ]

[ 150281-46-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 150281-46-2 ]
  • [ 93107-30-3 ]
  • [ 150281-72-4 ]
YieldReaction ConditionsOperation in experiment
73% Example 21 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[3-(3-pyridinyl)-1-pyrrolidinyl]-3-quinolinecarboxylic acid Starting from 1-cyclopropyl-6,7 difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid (1.06 g, 4.0 mmol) and 3-(3-pyrrolidinyl)pyridine, a procedure analogous to that given in Example 1 provided the title compound (1.15 g, 73percent) as an off white solid, mp 233°-236° C. 1 H-NMR (250 MHz, TFA): delta=1.35-1.42 (2H, m), 1.59 (2H, m), 2.39-2.57 (1H, m), 2.72-2.86 (1H, m), 3.92-4.23 (5H, m), 4.47-4.58 (1H, m), 7.42 (1H, d, J=7.1 Hz), 8.15-8.25 (2H, m), 8.78 (1H, d, J=8.4 Hz), 8.84 (1H, d, J=5.8 Hz), 8.98 (1H, br. s), 9.20 (1H, s), 11.63 (1H, br. s).
 

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