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Chemical Structure| 149489-18-9 Chemical Structure| 149489-18-9

Structure of 149489-18-9

Chemical Structure| 149489-18-9

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Product Details of [ 149489-18-9 ]

CAS No. :149489-18-9
Formula : C9H11BrO2
M.W : 231.09
SMILES Code : CCOC1=CC=C(Br)C=C1CO
MDL No. :MFCD06202636

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Application In Synthesis of [ 149489-18-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 149489-18-9 ]

[ 149489-18-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 149489-18-9 ]
  • [ 79636-94-5 ]
YieldReaction ConditionsOperation in experiment
In dichloromethane; 2) 5-Bromo-2-ethoxybenzyl alcohol (2.78 g, 12.0 mmol) and pyridinium dichromate (4.51 g, 12.0 mmol) in 120 ml of CH2 Cl2 was stirred at RT for 6 h. The mixture was filtered, washed with H2 O, 0.5 N HCl and brine and dried over Na2 SO4. The product was purified by silica gel column chromatography (EtOAc/petroleum ether 10:100) to give 5-bromo-2-ethoxybenzaldehyde. Yield: 2.33 g (85%). 1 H-NMR (250 MHz, CDCl3): δ10.4 (s, 1H, CHO), 7.91 (d, 1H, phenyl), 7.60 (dd, 1H, phenyl), 6.88 (d, 1H, phenyl), 4.14 (q, 2H, CH2 CH3), 1.51 (t, 3H, CH2 CH3).
 

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