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Chemical Structure| 143809-24-9 Chemical Structure| 143809-24-9

Structure of 143809-24-9

Chemical Structure| 143809-24-9

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Product Details of [ 143809-24-9 ]

CAS No. :143809-24-9
Formula : C10H10O3
M.W : 178.18
SMILES Code : O=CC1=CC=C2OCCOC2=C1C
MDL No. :MFCD22065850

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Application In Synthesis of [ 143809-24-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 143809-24-9 ]

[ 143809-24-9 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 143809-24-9 ]
  • [ 143809-21-6 ]
YieldReaction ConditionsOperation in experiment
61% With sodium hydroxide; sodium sulfite;palladium-carbon; In tetrahydrofuran; SYNTHETIC EXAMPLE 9 Production of 5-methyl-1,4-benzodioxan-6-carboxylic acid In 5 ml of tetrahydrofuran was dissolved 0.8 g of 5-methyl-1,4-benzodioxan-6-carbaldehyde, then 27 ml of a 1% sodium hydroxide aqueous solution was added dropwise to the solution and further 0.5 g of a 10% palladium-carbon was added thereto, and the mixture was refluxed under heating for 1.5 days. The mixture was cooled to room temperature, 10 ml of a 10% sodium sulfite aqueous solution was added thereto and after stirring for 30 minutes, the mixture was filtered and the tetrahyctrofuran was removed under reduced pressure. The residue was adjusted to pH 3 with a 5% hydrochloric acid and extracted with diethyl ether. The diethyl ether layer was washed successively with water and saturated saline solution and dried over anhydrous magnesium sulfate. The solvent was removed under reduced pressure to obtain 0.53 g of the titled 5-methyl-1,4-benzodioxan-6-carboxylic acid5-methyl-1,4-benzodioxan-6-carboxylic acid (yield: 61%). 1 H-NMR (CDCl3) delta(ppm): 2.51 (3H, S), 4.29 (4H, s), 6.76 (1H, d, J=8.6Hz), 7.62 (1H, d, J=8.6Hz), 11.98 (1H, brs)
  • 2
  • [ 143809-21-6 ]
  • [ 143809-24-9 ]
 

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