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Chemical Structure| 14292-44-5 Chemical Structure| 14292-44-5

Structure of 14292-44-5

Chemical Structure| 14292-44-5

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Product Details of [ 14292-44-5 ]

CAS No. :14292-44-5
Formula : C8H12N2S
M.W : 168.26
SMILES Code : NC1=NC2=C(CCCCC2)S1
MDL No. :MFCD02663887
InChI Key :RTUODTFOELDCNI-UHFFFAOYSA-N
Pubchem ID :4362935

Safety of [ 14292-44-5 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H319
Precautionary Statements:P305+P351+P338

Application In Synthesis of [ 14292-44-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 14292-44-5 ]

[ 14292-44-5 ] Synthesis Path-Downstream   1~18

  • 1
  • [ 766-66-5 ]
  • [ 17356-08-0 ]
  • [ 14292-44-5 ]
  • 3
  • [ 14292-44-5 ]
  • 5,6,7,8-tetrahydro-4<i>H</i>-cycloheptathiazole-2-diazonium; tetrafluoroborate [ No CAS ]
  • 5
  • [ 14292-44-5 ]
  • [ 619-41-0 ]
  • 1-(4-methylphenyl)-2-(5,6,7,8-tetrahydro-2-imino-4H-cycloheptathiazolyl)ethanone hydrobromide [ No CAS ]
  • 7
  • [ 14292-44-5 ]
  • [ 27225-20-3 ]
  • 8
  • [ 636-44-2 ]
  • [ 14292-44-5 ]
  • [ 1334598-92-3 ]
  • 11
  • [ 938261-59-7 ]
  • [ 14292-44-5 ]
  • [ 1431945-85-5 ]
  • 12
  • [ 14292-44-5 ]
  • ethyl 3-chloro-6,7,8,9-tetrahydro-5H-cyclohepta[d]imidazo[2,1-b]thiazole-2-carboxylate [ No CAS ]
  • 13
  • [ 14292-44-5 ]
  • C11H11ClN2O2S [ No CAS ]
  • 14
  • [ 14292-44-5 ]
  • 4-(3-chloro-6,7,8,9-tetrahydro-5H-cyclohepta[d]imidazo[2,1-b]thiazole-2-carbonyl)-1-cyclopentylpiperazin-2-one [ No CAS ]
  • 15
  • [ 70-23-5 ]
  • [ 14292-44-5 ]
  • ethyl 7-thia-2,5-diazatricyclo[6.5.0.02,6]trideca-1(8),3,5-triene-4-carboxylate [ No CAS ]
YieldReaction ConditionsOperation in experiment
3% In 1,2-dimethoxyethane; at 90℃; for 16h; Example 81 Ethyl 7-thia-2,5-diazatricyclo[6.5.0.02'6]trideca-l(8),3,5-triene-4-carboxylate To a solution of 4H,5H,6H,7H,8H-cyclohepta[d][l,3]thiazol-2 -amine (90%, 600 mg, 3.56 mmol) in DME (12 mL) was added ethyl 3-bromo-2-oxopropanoate (1.2 mL, 9.52 mmol) at room temperature and the reaction heated at 90C for 16 h. The solvent was evaporated, water was added to the remaining residue and the pH adjusted to ~8. The aqueous phase was extracted with EtOAc. The organic layer was dried ( a2S04), filtered and evaporated to dryness. The residue was purified twice; first by FCC (eluent: 1-40% ethyl acetate in n-hexane) and then by preparative TLC (eluent: 3% methanol in DCM) to afford the title compound as a red solid (22 mg, 3% yield); m/z = 265.4 (MH)+.
  • 16
  • [ 24280-93-1 ]
  • [ 14292-44-5 ]
  • (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methyl-N-(5,6,7,8-tetrahydro-4H-cyclohepta[d]thiazol-2-yl)hex-4-enamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
67% General procedure: To a solution of mycophenolic acid (2 mmol) in absolute DMF (1.5 mL) carbonyldiimidazole(2.2 mmol) was added and stirred for 2 h at room temperature. Then appropriate amine (2.2 mmol) wasadded and the reaction mixture is stirred at 70 C for 10 h. The mixture was cooled to room temperatureand distilled water (10 mL) was added. The precipitate formed was filtered and crystallized fromaqueous methanol.
  • 17
  • [ 53631-18-8 ]
  • [ 14292-44-5 ]
  • C16H17FN2S [ No CAS ]
  • 18
  • [ 14292-44-5 ]
  • [ 613-54-7 ]
  • C20H20N2S [ No CAS ]
 

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