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Chemical Structure| 142688-28-6 Chemical Structure| 142688-28-6

Structure of 142688-28-6

Chemical Structure| 142688-28-6

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Product Details of [ 142688-28-6 ]

CAS No. :142688-28-6
Formula : C15H11BrINO2S
M.W : 476.13
SMILES Code : O=S(N1C=C(I)C2=C1C=CC(Br)=C2)(C3=CC=C(C)C=C3)=O
MDL No. :MFCD13177492
InChI Key :UESGNBKPTQOFOP-UHFFFAOYSA-N
Pubchem ID :11016249

Safety of [ 142688-28-6 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 142688-28-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 142688-28-6 ]

[ 142688-28-6 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 142688-28-6 ]
  • [ 325142-82-3 ]
  • C22H15BrF3NO2S [ No CAS ]
YieldReaction ConditionsOperation in experiment
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate; In 1,2-dimethoxyethane; water; at 100℃;Microwave irradiation; General procedure: To the solution of corresponding compound 6 (0.58 mmol) in dimethoxyethane (2.0 mL) in microwave reaction vessel, were added compound 5 (0.53 mmol), Pd(PPh3)4 (0.018 g, 0.016 mmol) and aqueous 2M Na2CO3 solution (1.3 mL, 2.6 mmol). The reaction mixture was heated to 100 C by microwave irradiation with power of 100 W. After the completion of reaction was confirmed, solvent was removed in vaccuo. The residue was purified on flash column chromatography using n-hexane (Hex):EA (9:1) as an eluent to obtain compound 7.
  • 2
  • [ 765916-70-9 ]
  • [ 142688-28-6 ]
  • C23H17BrFNO3S [ No CAS ]
YieldReaction ConditionsOperation in experiment
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate; In 1,2-dimethoxyethane; water; at 100.0℃;Microwave irradiation; General procedure: To the solution of corresponding compound 6 (0.58 mmol) in dimethoxyethane (2.0 mL) in microwave reaction vessel, were added compound 5 (0.53 mmol), Pd(PPh3)4 (0.018 g, 0.016 mmol) and aqueous 2M Na2CO3 solution (1.3 mL, 2.6 mmol). The reaction mixture was heated to 100 C by microwave irradiation with power of 100 W. After the completion of reaction was confirmed, solvent was removed in vaccuo. The residue was purified on flash column chromatography using n-hexane (Hex):EA (9:1) as an eluent to obtain compound 7.
 

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Indoles

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