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Chemical Structure| 134578-93-1 Chemical Structure| 134578-93-1

Structure of 134578-93-1

Chemical Structure| 134578-93-1

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Product Details of [ 134578-93-1 ]

CAS No. :134578-93-1
Formula : C8H14BrNO
M.W : 220.11
SMILES Code : O=C1N(CCCCBr)CCC1
MDL No. :MFCD11213733

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Application In Synthesis of [ 134578-93-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 134578-93-1 ]

[ 134578-93-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 134578-93-1 ]
  • [ 127561-18-6 ]
  • [ 142494-17-5 ]
YieldReaction ConditionsOperation in experiment
With sodium carbonate; In dichloromethane; butan-1-ol; EXAMPLE III Method of Making 1-[4-[4-[6-(Trifluoromethvl)-2-Pyridinyl]-1-Piperazinyl]Butyl]-2-Pyrrolidinone (E)-2-butenedioate (1:1) salt 9 g of 1-(4-bromobutyl)-2-pyrrolidinone and 7.6 g of <strong>[127561-18-6]1-[6-(trifluoromethyl)-2-pyridinyl]-piperazine</strong> were mixed with 100 ml of butanol. 4.3 g of sodium carbonate were added, and the mixture is refluxed for 3 hours. The precipitate is filtered and washed with butanol, and the filtrate is then evaporated. The residue was dissolved in dichloromethane, washed with water, dried over anhydrous magnesium sulfate, after which the solvent was evaporated to obtain 12.5 g of 1-[4-[4-[6-(trifluoromethyl)-2-pyridinyl]-1-piperazinyl]-butyl]-2-pyrrolidinone.
 

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