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Chemical Structure| 1338225-97-0 Chemical Structure| 1338225-97-0
Chemical Structure| 1338225-97-0

Doravirine

CAS No.: 1338225-97-0

Doravirine is a non-nucleoside inhibitor of HIV-1 reverse transcriptase with potent activity against wild-type virus (95% inhibitory concentration 19 nM, 50% human serum).

Synonyms: MK-1439

4.5 *For Research Use Only !

Cat. No.: A367825 Purity: 98%

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Product Details of [ Doravirine ]

CAS No. :1338225-97-0
Formula : C17H11ClF3N5O3
M.W : 425.75
SMILES Code : N#CC1=CC(OC2=C(C(F)(F)F)C=CN(CC(N3C)=NNC3=O)C2=O)=CC(Cl)=C1
Synonyms :
MK-1439
MDL No. :MFCD22417167
InChI Key :ZIAOVIPSKUPPQW-UHFFFAOYSA-N
Pubchem ID :58460047

Safety of [ Doravirine ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT05761509 HIV Infections COMPLETED 2024-06-30 Service de maladies infectieus... More >>es et tropicales du CHU de Montpellier, Montpellier, 34295, France|Hopital Saint Antoine, Paris, 75012, France|Service de maladies infectieuses et tropicales de de l'h?pital La Pitié-Salpêtrière, Paris, 75013, France Less <<
NCT04495348 HIV-1-infection|Weight Gain COMPLETED 2023-06-05 University of Colorado Anschut... More >>z Medical Campus, Aurora, Colorado, 80045, United States|UTHealth, Houston, Texas, 77030, United States Less <<
NCT04900974 HIV Infections|Pregnancy Relat... More >>ed Less << PHASE1 RECRUITING 2025-07-25 University of North Carolina a... More >>t Chapel Hill, Chapel Hill, North Carolina, 27514, United States Less <<
NCT03894124 Human Immunodeficiency Virus PHASE1 COMPLETED 2019-08-06 Chelsea and Westminster Hospit... More >>al NHS Foundation Trust, London, SW10 9NH, United Kingdom Less <<
NCT05322083 Virus-HIV UNKNOWN 2025-01-24 -
NCT04334551 HIV Infections PHASE4 UNKNOWN 2022-10-01 Clinique Du Quartier Latin, Mo... More >>ntreal, Quebec, H2L 4E9, Canada|Clinique Du Quartier Latin, Montreal, Quebec, H2L 4E9, Canada|CHU Martinique, Fort-de-France, Fort De France, CS 90632, Martinique Less <<
NCT02641067 Renal Impairment PHASE1 COMPLETED 2016-05-25 -
NCT02089659 HIV-1 Infection PHASE1 COMPLETED 2014-05-12 -
NCT05202613 HIV UNKNOWN 2025-12-22 Department of Public Health an... More >>d Infectious Diseases, Rome, Italy/RM, 00185, Italy Less <<
NCT04689737 HIV-infected Participants With... More >> ESRD Undergoing Routine Hemodialysis Less << PHASE4 COMPLETED 2021-06-14 Germans Trias i Pujol Hospital... More >>, Badalona, Barcelona, 08916, Spain|Universitario Bellvitge Hospital, Hospitalet de Llobregat, Barcelona, 08907, Spain|Valle Hebron Hospital, Barcelona, 08035, Spain Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.35mL

0.47mL

0.23mL

11.74mL

2.35mL

1.17mL

23.49mL

4.70mL

2.35mL

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