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Chemical Structure| 1184181-48-3 Chemical Structure| 1184181-48-3

Structure of 1184181-48-3

Chemical Structure| 1184181-48-3

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Product Details of [ 1184181-48-3 ]

CAS No. :1184181-48-3
Formula : C10H12O4
M.W : 196.20
SMILES Code : O=C(O)C1=CC(C(C)C)=C(O)C=C1O
MDL No. :MFCD16996083
Boiling Point : No data available
InChI Key :JAMMFVLHQOLNOP-UHFFFAOYSA-N
Pubchem ID :71700011

Safety of [ 1184181-48-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 1184181-48-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1184181-48-3 ]

[ 1184181-48-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1184181-48-3 ]
  • [ 5271-27-2 ]
  • (2,4-dihydroxy-5-isopropylphenyl)(4-methyl-2-phenylpiperazin-1-yl)methanone [ No CAS ]
YieldReaction ConditionsOperation in experiment
27% With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 120℃; for 3h;Microwave irradiation; Compound 6 (0.20 g, 1.02 mmol), <strong>[5271-27-2]1-methyl-3-phenylpiperazine</strong> (0.22 g, 1.22 mmol) obtained in the above,Ethyl-3- (3-dimethylaminopropyl) carbodiimide (0.39 g, 2.04 mmol),1-hydroxybenzotriazole (0.13 g, 1.02 mmol), 1-hydroxybenzotriazoleN, N-diisopropylethylamine (0.18 mL, 1.02 mmol) and N, N-diisopropylethylamineThe mixture of 4 mL of solvent DMF was mixed well at the same time while performing a microwave irradiation (Biotage Initiator) at 120 ° C for 3 hours. The mixture was concentrated under reduced pressure, And purified by MPLC (Biotage SNAP Cartridge KP-C18-HS column) to obtain Compound 1 at a yield of 27percent. Rf = 0.32 (8: 2 ethyl acetate: hexane).
 

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