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Chemical Structure| 104336-01-8 Chemical Structure| 104336-01-8

Structure of 104336-01-8

Chemical Structure| 104336-01-8

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Product Details of [ 104336-01-8 ]

CAS No. :104336-01-8
Formula : C8H13NO3
M.W : 171.19
SMILES Code : CCOC(C1=CN=CO1)OCC
MDL No. :MFCD16988831

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Application In Synthesis of [ 104336-01-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 104336-01-8 ]

[ 104336-01-8 ] Synthesis Path-Downstream   1~2

  • 2
  • [ 75-09-2 ]
  • [ 7732-18-5 ]
  • [ 104336-01-8 ]
  • [ 118994-86-8 ]
YieldReaction ConditionsOperation in experiment
With trifluoroacetic acid; In hexane; toluene; C. 5-Oxazolecarboxaldehyde A flask was charged with 5-((diethoxy)methyl)oxazole (1.02 g, 0.00596 mol) and cooled to 0 C. A solution of trifluoroacetic acid/CH2 Cl2 (1:1 (v/v), 6.7 mL) and H2 O (0.39 mL) was added and the solution stirred at 0 C. for 10 min. The solvent was removed in vacuo, and the residue was treated with toluene and concentrated. Chromatography on a 100 g SiO2 flash column with a gradient of EtOAc/hexane (20%, 30%, 40%) afforded the desired compound as a colorless liquid (0.344 g, 0.00354 mol, 59%): 1 H NMR (CDCl3) d 7.89 (s, 1H), 8.12 (s, 1H), 9.87 (s, 1H). Mass spectrum: (M+H)+ =98.
 

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