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Chemical Structure| 103792-80-9 Chemical Structure| 103792-80-9

Structure of 103792-80-9

Chemical Structure| 103792-80-9

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Product Details of [ 103792-80-9 ]

CAS No. :103792-80-9
Formula : C5H3Cl2NO2
M.W : 179.99
SMILES Code : OC1=NC=C(Cl)C(O)=C1Cl

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Application In Synthesis of [ 103792-80-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 103792-80-9 ]

[ 103792-80-9 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 103792-81-0 ]
  • [ 103792-80-9 ]
  • 2
  • [ 103792-80-9 ]
  • [ 103766-25-2 ]
YieldReaction ConditionsOperation in experiment
86% With acetic acid; sodium iodide; In acetonitrile; at 60℃; for 8h; A mixture of compound 6 (8.0 g, 44 mmol), acetonitrile (100 mL), acetic acid (3 mL)and sodium iodide (13.2 g, 88 mmol) was heated for 8 h at 60 °C. Then the mixture was cooled to room temperature and poured into 10percent sodium thiosulfate solution (200 mL) to precipitate a colourless solid, which was recrystallised from water to give pure compound 2: Yield 5.6 g (86percent); m.p.272?273 °C (lit.7 273?274 °C); 1H NMR (400 MHz, DMSO-d6): delta 5.70(s, 1H), 7.51 (s, 1H), 11.29 (br, 2H) ; 13C NMR (100 MHz, DMSO-d6): delta163.5, 163.2, 134.6, 105.6, 98.7; LRMS (ESI) m/z (percent): 146 (100) [M (35Cl+ 1]+, 148 (30) [M (37Cl) + 1]+; HRMS (ESI) m/z calcd for C5H535ClNO2:[M + H]+: 146.0003; found: 146.0012; calcd for C5H537ClNO2: [M + H]+:147.9975; found: 147.9975.
 

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