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Chemical Structure| 1011244-70-4 Chemical Structure| 1011244-70-4

Structure of 1011244-70-4

Chemical Structure| 1011244-70-4

N-(4-Aminophenyl)-4-trifluoromethylbenzamide

CAS No.: 1011244-70-4

4.5 *For Research Use Only !

Cat. No.: A647438 Purity: 95%

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Product Details of [ 1011244-70-4 ]

CAS No. :1011244-70-4
Formula : C14H11F3N2O
M.W : 280.25
SMILES Code : O=C(NC1=CC=C(N)C=C1)C2=CC=C(C(F)(F)F)C=C2

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Application In Synthesis of [ 1011244-70-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1011244-70-4 ]

[ 1011244-70-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1011244-70-4 ]
  • [ 13790-39-1 ]
  • N-(4-((6,7-dimethoxyquinazolin-4-yl)amino)phenyl)-4-(trifluoromethyl)benzamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
84% With trifluoroacetic acid; In isopropyl alcohol; at 85℃; for 0.5h;Inert atmosphere; General procedure: To a solution of 13a-u (0.4 mmol) and <strong>[13790-39-1]4-chloro-6,7-dimethoxyquinazoline</strong> (0.09g, 0.4 mmol) in isopropanol (10 mL) were added two drops of trifluoroacetic acid (TFA). The reaction was refluxed at 85 oC for 30 min. Upon completion, the reaction mixture is cooled to 0 oC in an ice bath. The precipitated solid was filtered and washed with cold methanol and dried to give the title compounds 14a-u.
 

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