Structure of 10016-52-1
*Storage:
*Shipping:
CAS No. : | 10016-52-1 |
Formula : | C12H6Br2O |
M.W : | 325.98 |
SMILES Code : | BrC1=CC=C(OC2=CC=C(Br)C=C23)C3=C1 |
MDL No. : | MFCD00093683 |
InChI Key : | UFCZRCPQBWIXTR-UHFFFAOYSA-N |
Pubchem ID : | 82290 |
GHS Pictogram: | ![]() |
Signal Word: | Warning |
Hazard Statements: | H302 |
Precautionary Statements: | P280-P305+P351+P338 |
Num. heavy atoms | 15 |
Num. arom. heavy atoms | 13 |
Fraction Csp3 | 0.0 |
Num. rotatable bonds | 0 |
Num. H-bond acceptors | 1.0 |
Num. H-bond donors | 0.0 |
Molar Refractivity | 69.12 |
TPSA ? Topological Polar Surface Area: Calculated from | 13.14 Ų |
Log Po/w (iLOGP)? iLOGP: in-house physics-based method implemented from | 3.1 |
Log Po/w (XLOGP3)? XLOGP3: Atomistic and knowledge-based method calculated by | 5.78 |
Log Po/w (WLOGP)? WLOGP: Atomistic method implemented from | 5.11 |
Log Po/w (MLOGP)? MLOGP: Topological method implemented from | 4.16 |
Log Po/w (SILICOS-IT)? SILICOS-IT: Hybrid fragmental/topological method calculated by | 4.75 |
Consensus Log Po/w? Consensus Log Po/w: Average of all five predictions | 4.58 |
Log S (ESOL):? ESOL: Topological method implemented from | -6.14 |
Solubility | 0.000234 mg/ml ; 0.000000718 mol/l |
Class? Solubility class: Log S scale | Poorly soluble |
Log S (Ali)? Ali: Topological method implemented from | -5.83 |
Solubility | 0.000488 mg/ml ; 0.0000015 mol/l |
Class? Solubility class: Log S scale | Moderately soluble |
Log S (SILICOS-IT)? SILICOS-IT: Fragmental method calculated by | -6.64 |
Solubility | 0.0000743 mg/ml ; 0.000000228 mol/l |
Class? Solubility class: Log S scale | Poorly soluble |
GI absorption? Gatrointestinal absorption: according to the white of the BOILED-Egg | High |
BBB permeant? BBB permeation: according to the yolk of the BOILED-Egg | Yes |
P-gp substrate? P-glycoprotein substrate: SVM model built on 1033 molecules (training set) | No |
CYP1A2 inhibitor? Cytochrome P450 1A2 inhibitor: SVM model built on 9145 molecules (training set) | Yes |
CYP2C19 inhibitor? Cytochrome P450 2C19 inhibitor: SVM model built on 9272 molecules (training set) | Yes |
CYP2C9 inhibitor? Cytochrome P450 2C9 inhibitor: SVM model built on 5940 molecules (training set) | Yes |
CYP2D6 inhibitor? Cytochrome P450 2D6 inhibitor: SVM model built on 3664 molecules (training set) | No |
CYP3A4 inhibitor? Cytochrome P450 3A4 inhibitor: SVM model built on 7518 molecules (training set) | No |
Log Kp (skin permeation)? Skin permeation: QSPR model implemented from | -4.18 cm/s |
Lipinski? Lipinski (Pfizer) filter: implemented from | 1.0 |
Ghose? Ghose filter: implemented from | None |
Veber? Veber (GSK) filter: implemented from | 0.0 |
Egan? Egan (Pharmacia) filter: implemented from | 0.0 |
Muegge? Muegge (Bayer) filter: implemented from | 2.0 |
Bioavailability Score? Abbott Bioavailability Score: Probability of F > 10% in rat | 0.55 |
PAINS? Pan Assay Interference Structures: implemented from | 0.0 alert |
Brenk? Structural Alert: implemented from | 0.0 alert: heavy_metal |
Leadlikeness? Leadlikeness: implemented from | No; 1 violation:MW<1.0 |
Synthetic accessibility? Synthetic accessibility score: from 1 (very easy) to 10 (very difficult) | 2.59 |
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
87% | With bromine; In acetic acid; at 120℃; for 6h;Inert atmosphere; | To a round bottom flask, Diphenylene-oxide (8.40 g, 50 mmol), bromine (2.6 mL) dissolved in 30 mL glacial acetic acid were added. The resultant suspension was heating for 6 h under nitrogen at 120 C. After cooling to 25 C, the intermediate product 2 was recovered by filtration and recrystallization in acetic acid and vacuum drying as a white solid (12.2 g, 75%). 1H NMR (400 MHz,CDCl3) d (ppm): 8.03 (s, 2H), 7.58 (d, J 8.0 Hz, 2H), 7.44 (d, J 8 Hz,2H) (Fig. S27) [46]. To a solution of 2 (0.324 g, 1.0 mmol) and 4-([2,2': 6', 2''- terpyridyl]-4'-) - benzene boric acid (0.88 g,2.50 mmol) in THF (100 mL), aqueous NaOH (160 mg, 4.0 mmol) was added. The mixture was degassed for 10 min, then Pd(PPh3)4(115 mg, 0.10 mmol) was added. Following the procedure L1, thepure product L2was obtained as a white solid (0.55 g, 70%). |
78% | With bromine; In chloroform; at 0 - 20℃;Inert atmosphere; | Under a N2 atmosphere, bromine (1.4 ml, 27.3 mmol) was added dropwise at 0 C to a solution of dibenzofuran (2.0 g, 11.9 mmol) in chloroform (20 mL). After the addition, the reaction mixture was allowed to warm up to room temperature and stirred overnight. Then the reaction mixture was quenched with water and extracted with CH2Cl2 (3×30 mL). The organic layer was dried over anhydrous Na2SO4, filtered and evaporated to dryness. The resulted crude product was purified by column chromatography on silica gel using petroleum ether/CH2Cl2 (10/1, v/v) as eluent to afford white powder (3.0 g, 78%). 1H NMR (400 MHz, CDCl3): delta (ppm) 7.44 (d, J = 8.8 Hz, 2H), 7.57 (dd, J = 2 Hz, 2H), 8.02 (d, J = 2 Hz, 2H). |
75.7% | With bromine; In dichloromethane; at 0 - 20℃;Inert atmosphere; | To a mixture of dibenzo(b,d)furan (4g, 23.8 mmol) and CH2CI2 (100 ml), was added bromine (3.66 ml, 71 .4 mmol) at 0C under nitrogen atmosphere. The reactionmixture was stirred at room temperature overnight. The organic layer was collectedand concentrated in vacuo to yield a solid product. The product obtained wasrecrystallized using CH2CI2 to afford compound (Example 14-1)asawhite solid (5.85g, 75.7%) |
75.07% | With N-Bromosuccinimide; In N,N-dimethyl-formamide; at 25℃; for 5h; | (10 g, 59 mmol, 1.0 eq) was dissolved in 30 ml of dimethylformamide and slowly added at 25 C to a flask in which 30 ml of dibenzo [b, d] furan was dissolved in 30 ml of dimethylformamide, followed by addition of n-bromosuccinimide (21.69 g, 121 mmol, 2.05 eq) do.After 5 hours of reaction, the reaction mixture was precipitated with 200 ml of distilled water, filtered and dried to obtain 14.55 g of the title compound (yield: 75.07%). |
65% | With bromine; In dichloromethane; at 0 - 20℃; for 12.7h;Inert atmosphere; | (1) Synthesis of Compound (291-a) [0252] [0253] Into a three-necked flask, 168.1 g (1000 mmol) of dibenzofuran and 1600 ml of dichloromethane were charged, and the reaction vessel was cooled to 0 C in a nitrogen atmosphere. After adding 125 ml of a dichloromethane solution of 255.8 g of bromine dropwise into the reaction vessel over 40 min, the contents were stirred at room temperature for 12 h. After the reaction, the reaction vessel was cooled to 0 C and then 500 ml of water and 100 ml of a 20% aqueous solution of NaHSO4 were added. The resultant solution was extracted with several portions of dichloromethane in a separatory funnel. The extract was washed with 300 ml of a I N aqueous solution of sodium hydroxide, dried over anhydrous magnesium sulfate, filtered, and concentrated. The concentrate was dispersed in hexane for washing, to obtain a white solid. [0254] The yield was 212 g and the percent, yield was 65%. |
65% | With bromine; In dichloromethane; at 0 - 20℃; for 12h;Inert atmosphere; | (1) Synthesis of compound (140-a) [0243] [0244] In a three-neck flask, 168.1g (1000 mmol) of dibenzofuran and 1600 ml of dichloromethane were placed. The reactor was cooled to 0C in a nitrogen atmosphere. To the reactor, 125 mL of a dichloromethane solution of 255.8g of bromine was added dropwise over 40 minutes, and the resultant was stirred at room temperature for 12 hours. [0245] After completion of the reaction, the reactor was cooled to 0C. 500 mL of water was added, and further, 100 ml of a 20% aqueous NaHSO4 solution was added. The sample solution was transferred to a separating funnel, and extracted with dichloromethane several times. The resultant was washed with 300 ml of a 1 N aqueous sodium hydroxide solution and dried with anhydrous magnesium sulfate, filtrated and concentrated. The resulting product was washed by dispersing in hexane, whereby white solids were obtained. The yield was 212g (65%). |
40% | With bromine; In tetrachloromethane; chloroform; at 20℃; for 168h; | In a 500 mL three-neck flask were put 8.4 g (50 mmol) of dibenzofuran and 100 mL of carbon tetrachloride. A solution prepared by dissolving 17 g (110 mmol) of bromine in 50 mL of chloroform was dripped through a dropping funnel into the three-neck flask over about 20 minutes. Then, this solution was stirred at room temperature for 7 days. After that, this solution was washed with a saturated solution of sodium hydrogen carbonate, an aqueous solution of sodium thiosulfate and saturated brine. The organic layer was dried with magnesium sulfate, and this mixture was gravity filtered. The resulting filtrate was concentrated, and the obtained solid was recrystallized from chloroform. Accordingly, 6.4 g of a white powder was obtained in 40 % yield, which was the substance to be produced. |
38% | With bromine; In acetic acid; at 75℃; for 3h; | 1a) 2,8-Dibromodibenzofuran Bromine (92.6 g, 0.58 mol) in acetic acid (54 g) is added at 75 C. to a solution of dibenzofuran (23.2 g, 0.14 mol) in acetic acid (232 g). The mixture is then stirred at 75 C. for 3 hours. The reaction mixture is cooled to room temperature and poured into H2O. The orange solid is washed with Na2S2O3 aq. and H2O. The crude product is then purified by recrystallization from n-hexane, wherein the pure product is obtained as a white solid (38% yield; mp.: 226 C.). 1H-NMR (CDCl3, ppm): 7.65 (d, 2H), 7.59 (dd, 2H), 8.03 (d, 2H). |
32% | With bromine; acetic acid; In water; toluene; | (1) Synthesis of 2,8-dibromodibenzofuran A three-necked flask was charged with dibenzofuran (100.91 g, 600 mmol) and 300 ml of AcOH and the contents were heated to 40 C. Then, a solution of Br2 (191.8 g, 1200 mmol)/AcOH 300 ml was added dropwise. After stirring for 9 h at 40 C., the mixture was refluxed for 6 h. After the reaction, the reaction production solution was cooled to room temperature and added with 600 ml of water. The precipitate collected by filtration was dissolved in toluene. The resultant solution was dried over anhydrous magnesium sulfate, filtrated and concentrated. The obtained solid product was recrystallized from hexane five times to obtain the titled compound (62.83 g, 32% yield). |
With bromine; In acetic acid; at 20℃;Reflux; Inert atmosphere; | A 250 ml round bottom flask containing 8.4 g (50 mmol) of dibenzofuran dissolved in 100 ml of glacial acetic acid wasequipped with an addition funnel. Bromine 5.13 ml (100 mmol) in 30 ml of glacial acetic acid was added dropwise via the addition funnel to the dibenzofuran under constant stirring. This reaction mixture was stirred at room temperature for 4 h. It was then refluxed for 6 h, cooled. The solid was then collected by filtration and washed with three 100 ml portions of water. Recrystallization from 100 ml of acetic anhydride obtained 12.2 g (75%) pure 2,8-dibromodibenzofuran (1) as a white solid | |
With bromine; In chloroform; at 25℃; for 48h; | [0001082] To a solution of Compound 302A (1 g, 0.59 mmol) in CHC13 (6 mL) was added bromine (0.68 mL, 13.26 mmol) at 0 C. The mixture was stirred at 25 C for 48 h. It was poured into aq. Na2S203 (50 mL) and extracted with ethyl acetate (20 mL x 3). The combined organic layers were washed with brine (30 mL), dried over anhydrous sodium sulfate, and concentrated in vacuo to furnish the crude product. It was recrystallized from methanol to give Compound 302B. |
Tags: 10016-52-1 synthesis path| 10016-52-1 SDS| 10016-52-1 COA| 10016-52-1 purity| 10016-52-1 application| 10016-52-1 NMR| 10016-52-1 COA| 10016-52-1 structure
A267985 [955959-84-9]
4-(4-Bromophenyl)dibenzo[b,d]furan
Similarity: 0.96
A267985 [955959-84-9]
4-(4-Bromophenyl)dibenzo[b,d]furan
Similarity: 0.96
Precautionary Statements-General | |
Code | Phrase |
P101 | If medical advice is needed,have product container or label at hand. |
P102 | Keep out of reach of children. |
P103 | Read label before use |
Prevention | |
Code | Phrase |
P201 | Obtain special instructions before use. |
P202 | Do not handle until all safety precautions have been read and understood. |
P210 | Keep away from heat/sparks/open flames/hot surfaces. - No smoking. |
P211 | Do not spray on an open flame or other ignition source. |
P220 | Keep/Store away from clothing/combustible materials. |
P221 | Take any precaution to avoid mixing with combustibles |
P222 | Do not allow contact with air. |
P223 | Keep away from any possible contact with water, because of violent reaction and possible flash fire. |
P230 | Keep wetted |
P231 | Handle under inert gas. |
P232 | Protect from moisture. |
P233 | Keep container tightly closed. |
P234 | Keep only in original container. |
P235 | Keep cool |
P240 | Ground/bond container and receiving equipment. |
P241 | Use explosion-proof electrical/ventilating/lighting/equipment. |
P242 | Use only non-sparking tools. |
P243 | Take precautionary measures against static discharge. |
P244 | Keep reduction valves free from grease and oil. |
P250 | Do not subject to grinding/shock/friction. |
P251 | Pressurized container: Do not pierce or burn, even after use. |
P260 | Do not breathe dust/fume/gas/mist/vapours/spray. |
P261 | Avoid breathing dust/fume/gas/mist/vapours/spray. |
P262 | Do not get in eyes, on skin, or on clothing. |
P263 | Avoid contact during pregnancy/while nursing. |
P264 | Wash hands thoroughly after handling. |
P265 | Wash skin thouroughly after handling. |
P270 | Do not eat, drink or smoke when using this product. |
P271 | Use only outdoors or in a well-ventilated area. |
P272 | Contaminated work clothing should not be allowed out of the workplace. |
P273 | Avoid release to the environment. |
P280 | Wear protective gloves/protective clothing/eye protection/face protection. |
P281 | Use personal protective equipment as required. |
P282 | Wear cold insulating gloves/face shield/eye protection. |
P283 | Wear fire/flame resistant/retardant clothing. |
P284 | Wear respiratory protection. |
P285 | In case of inadequate ventilation wear respiratory protection. |
P231 + P232 | Handle under inert gas. Protect from moisture. |
P235 + P410 | Keep cool. Protect from sunlight. |
Response | |
Code | Phrase |
P301 | IF SWALLOWED: |
P304 | IF INHALED: |
P305 | IF IN EYES: |
P306 | IF ON CLOTHING: |
P307 | IF exposed: |
P308 | IF exposed or concerned: |
P309 | IF exposed or if you feel unwell: |
P310 | Immediately call a POISON CENTER or doctor/physician. |
P311 | Call a POISON CENTER or doctor/physician. |
P312 | Call a POISON CENTER or doctor/physician if you feel unwell. |
P313 | Get medical advice/attention. |
P314 | Get medical advice/attention if you feel unwell. |
P315 | Get immediate medical advice/attention. |
P320 | |
P302 + P352 | IF ON SKIN: wash with plenty of soap and water. |
P321 | |
P322 | |
P330 | Rinse mouth. |
P331 | Do NOT induce vomiting. |
P332 | IF SKIN irritation occurs: |
P333 | If skin irritation or rash occurs: |
P334 | Immerse in cool water/wrap n wet bandages. |
P335 | Brush off loose particles from skin. |
P336 | Thaw frosted parts with lukewarm water. Do not rub affected area. |
P337 | If eye irritation persists: |
P338 | Remove contact lenses, if present and easy to do. Continue rinsing. |
P340 | Remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P341 | If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P342 | If experiencing respiratory symptoms: |
P350 | Gently wash with plenty of soap and water. |
P351 | Rinse cautiously with water for several minutes. |
P352 | Wash with plenty of soap and water. |
P353 | Rinse skin with water/shower. |
P360 | Rinse immediately contaminated clothing and skin with plenty of water before removing clothes. |
P361 | Remove/Take off immediately all contaminated clothing. |
P362 | Take off contaminated clothing and wash before reuse. |
P363 | Wash contaminated clothing before reuse. |
P370 | In case of fire: |
P371 | In case of major fire and large quantities: |
P372 | Explosion risk in case of fire. |
P373 | DO NOT fight fire when fire reaches explosives. |
P374 | Fight fire with normal precautions from a reasonable distance. |
P376 | Stop leak if safe to do so. Oxidising gases (section 2.4) 1 |
P377 | Leaking gas fire: Do not extinguish, unless leak can be stopped safely. |
P378 | |
P380 | Evacuate area. |
P381 | Eliminate all ignition sources if safe to do so. |
P390 | Absorb spillage to prevent material damage. |
P391 | Collect spillage. Hazardous to the aquatic environment |
P301 + P310 | IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
P301 + P312 | IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
P301 + P330 + P331 | IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. |
P302 + P334 | IF ON SKIN: Immerse in cool water/wrap in wet bandages. |
P302 + P350 | IF ON SKIN: Gently wash with plenty of soap and water. |
P303 + P361 + P353 | IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. |
P304 + P312 | IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell. |
P304 + P340 | IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. |
P304 + P341 | IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P305 + P351 + P338 | IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
P306 + P360 | IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes. |
P307 + P311 | IF exposed: call a POISON CENTER or doctor/physician. |
P308 + P313 | IF exposed or concerned: Get medical advice/attention. |
P309 + P311 | IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician. |
P332 + P313 | IF SKIN irritation occurs: Get medical advice/attention. |
P333 + P313 | IF SKIN irritation or rash occurs: Get medical advice/attention. |
P335 + P334 | Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages. |
P337 + P313 | IF eye irritation persists: Get medical advice/attention. |
P342 + P311 | IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. |
P370 + P376 | In case of fire: Stop leak if safe to Do so. |
P370 + P378 | In case of fire: |
P370 + P380 | In case of fire: Evacuate area. |
P370 + P380 + P375 | In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion. |
P371 + P380 + P375 | In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion. |
Storage | |
Code | Phrase |
P401 | |
P402 | Store in a dry place. |
P403 | Store in a well-ventilated place. |
P404 | Store in a closed container. |
P405 | Store locked up. |
P406 | Store in corrosive resistant/ container with a resistant inner liner. |
P407 | Maintain air gap between stacks/pallets. |
P410 | Protect from sunlight. |
P411 | |
P412 | Do not expose to temperatures exceeding 50 oC/ 122 oF. |
P413 | |
P420 | Store away from other materials. |
P422 | |
P402 + P404 | Store in a dry place. Store in a closed container. |
P403 + P233 | Store in a well-ventilated place. Keep container tightly closed. |
P403 + P235 | Store in a well-ventilated place. Keep cool. |
P410 + P403 | Protect from sunlight. Store in a well-ventilated place. |
P410 + P412 | Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF. |
P411 + P235 | Keep cool. |
Disposal | |
Code | Phrase |
P501 | Dispose of contents/container to ... |
P502 | Refer to manufacturer/supplier for information on recovery/recycling |
Physical hazards | |
Code | Phrase |
H200 | Unstable explosive |
H201 | Explosive; mass explosion hazard |
H202 | Explosive; severe projection hazard |
H203 | Explosive; fire, blast or projection hazard |
H204 | Fire or projection hazard |
H205 | May mass explode in fire |
H220 | Extremely flammable gas |
H221 | Flammable gas |
H222 | Extremely flammable aerosol |
H223 | Flammable aerosol |
H224 | Extremely flammable liquid and vapour |
H225 | Highly flammable liquid and vapour |
H226 | Flammable liquid and vapour |
H227 | Combustible liquid |
H228 | Flammable solid |
H229 | Pressurized container: may burst if heated |
H230 | May react explosively even in the absence of air |
H231 | May react explosively even in the absence of air at elevated pressure and/or temperature |
H240 | Heating may cause an explosion |
H241 | Heating may cause a fire or explosion |
H242 | Heating may cause a fire |
H250 | Catches fire spontaneously if exposed to air |
H251 | Self-heating; may catch fire |
H252 | Self-heating in large quantities; may catch fire |
H260 | In contact with water releases flammable gases which may ignite spontaneously |
H261 | In contact with water releases flammable gas |
H270 | May cause or intensify fire; oxidizer |
H271 | May cause fire or explosion; strong oxidizer |
H272 | May intensify fire; oxidizer |
H280 | Contains gas under pressure; may explode if heated |
H281 | Contains refrigerated gas; may cause cryogenic burns or injury |
H290 | May be corrosive to metals |
Health hazards | |
Code | Phrase |
H300 | Fatal if swallowed |
H301 | Toxic if swallowed |
H302 | Harmful if swallowed |
H303 | May be harmful if swallowed |
H304 | May be fatal if swallowed and enters airways |
H305 | May be harmful if swallowed and enters airways |
H310 | Fatal in contact with skin |
H311 | Toxic in contact with skin |
H312 | Harmful in contact with skin |
H313 | May be harmful in contact with skin |
H314 | Causes severe skin burns and eye damage |
H315 | Causes skin irritation |
H316 | Causes mild skin irritation |
H317 | May cause an allergic skin reaction |
H318 | Causes serious eye damage |
H319 | Causes serious eye irritation |
H320 | Causes eye irritation |
H330 | Fatal if inhaled |
H331 | Toxic if inhaled |
H332 | Harmful if inhaled |
H333 | May be harmful if inhaled |
H334 | May cause allergy or asthma symptoms or breathing difficulties if inhaled |
H335 | May cause respiratory irritation |
H336 | May cause drowsiness or dizziness |
H340 | May cause genetic defects |
H341 | Suspected of causing genetic defects |
H350 | May cause cancer |
H351 | Suspected of causing cancer |
H360 | May damage fertility or the unborn child |
H361 | Suspected of damaging fertility or the unborn child |
H361d | Suspected of damaging the unborn child |
H362 | May cause harm to breast-fed children |
H370 | Causes damage to organs |
H371 | May cause damage to organs |
H372 | Causes damage to organs through prolonged or repeated exposure |
H373 | May cause damage to organs through prolonged or repeated exposure |
Environmental hazards | |
Code | Phrase |
H400 | Very toxic to aquatic life |
H401 | Toxic to aquatic life |
H402 | Harmful to aquatic life |
H410 | Very toxic to aquatic life with long-lasting effects |
H411 | Toxic to aquatic life with long-lasting effects |
H412 | Harmful to aquatic life with long-lasting effects |
H413 | May cause long-lasting harmful effects to aquatic life |
H420 | Harms public health and the environment by destroying ozone in the upper atmosphere |
Sorry,this product has been discontinued.
Home
* Country/Region
* Quantity Required :
* Cat. No.:
* CAS No :
* Product Name :
* Additional Information :
Total Compounds: mg
The concentration of the dissolution solution you need to prepare is mg/mL