Heck Reaction
The Heck reaction is a well-known chemical reaction, independently discovered by Mizoroki and Heck in 1972. It entails a cross-coupling reaction between organohalides and alkenes, where these compounds react in the presence of a palladium catalyst and a base, resulting in the formation of a substituted alkene.

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[1]Littke A F, Fu G C. Heck Reactions in the Presence of P (t-Bu)(3): Expanded Scope and Milder Reaction Conditions for the Coupling of Aryl Chlorides[J]. The Journal of organic chemistry, 1999, 64(1): 10-11.
[2]Rawal V H, Iwasa S. A short, stereocontrolled synthesis of strychnine[J]. The Journal of Organic Chemistry, 1994, 59(10): 2685-2686.
[3]Yang C, Lee H M, Nolan S P. Highly efficient Heck reactions of aryl bromides with n-butyl acrylate mediated by a palladium/phosphine− imidazolium salt system[J]. Organic Letters, 2001, 3(10): 1511-1514.
[4]Xu H J, Zhao Y Q, Zhou X F. Palladium-catalyzed Heck reaction of aryl chlorides under mild conditions promoted by organic ionic bases[J]. The Journal of Organic Chemistry, 2011, 76(19): 8036-8041.
[5]Sabounchei S J, Ahmadi M, Azizi T, et al. A Robust, Moisture-and Air-Stable Phosphine Mono-Ylide Palladacycle Precatalyst: A Simple and Highly Efficient System for Mizoroki-Heck Reactions[J]. Synlett, 2014, 25(03): 336-342.
[6]Harris M R, Konev M O, Jarvo E R. Enantiospecific intramolecular Heck reactions of secondary benzylic ethers[J]. Journal of the American Chemical Society, 2014, 136(22): 7825-7828.
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