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Levosimendan is a calcium sensitiser used in the management of acutely decompensated congestive heart failure.
Synonyms: Simsndan; OR-1259; simendan
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Batch number can be found on the product's label following the word 'Batch'.
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CAS No. : | 141505-33-1 |
Formula : | C14H12N6O |
M.W : | 280.29 |
SMILES Code : | N#CC(C#N)=NNC1=CC=C(C([C@H](C)C2)=NNC2=O)C=C1 |
Synonyms : |
Simsndan; OR-1259; simendan
|
MDL No. : | MFCD00867135 |
InChI Key : | WHXMKTBCFHIYNQ-SECBINFHSA-N |
Pubchem ID : | 3033825 |
GHS Pictogram: | ![]() |
Signal Word: | Warning |
Hazard Statements: | H302-H312-H332 |
Precautionary Statements: | P280 |
Clinical Trial:
NCT Number | Conditions | Phases | Recruitment | Completion Date | Locations |
NCT03281317 | - | Recruiting | December 15, 2020 | France ... More >> CHU Amiens Picardie Recruiting Amiens, France, 80054 Contact: Pierre-Gregoire GUINOT Less << | |
NCT03632837 | Cardiac Arrest ... More >> Resuscitation Inflammation Multi-Organ Disorder Less << | Not Applicable | Recruiting | September 2019 | Germany ... More >> University Hospital Hamburg-Eppendorf Recruiting Hamburg, Germany, 20246 Contact: Jens Kubitz, Prof. Dr. +49 (0) 40 7410 - 52415 j.kubitz@uke.de Contact: Eike Pfefferkorn, Dr. e.pfefferkorn@uke.de Less << |
NCT02627378 | MERS-CoV Infection ... More >> Refractory Hypoxemia Less << | Phase 1 | Completed | - | Saudi Arabia ... More >> Dammam University KFHU Al-Khobar, EP, Saudi Arabia, 31952 Less << |
NCT02141607 | - | Completed | - | Belgium ... More >> Department of Intensive Care, Erasme University Hospital Brussels, Belgium Spain Servei de Medicina Intensiva, Hospital Universitari Mútua Terrassa Barcelona, Spain Switzerland Intensive Care Division, Geneva University Hospitals Geneva, Switzerland Less << | |
NCT02046954 | - | Completed | - | Germany ... More >> Charité Universitätsmedizin Berin Berlin, Germany, 10117 Less << | |
NCT03436095 | - | Recruiting | July 30, 2020 | China, Guangdong ... More >> Shenzhen Second People's Hospital Recruiting Shenzhen, Guangdong, China Contact: Yang Guozhao +86075583003435 yangguozhao123@qq.com Less << | |
NCT03555123 | Acute Decompensated Heart Fail... More >>ure Less << | Phase 3 | Not yet recruiting | May 30, 2019 | - |
NCT01219712 | Left Ventricular Dysfunction ... More >> Femoral Fracture Less << | Not Applicable | Unknown | February 2013 | Sweden ... More >> Department of Anaesthesia & Intensive Care Not yet recruiting Jönköping, Sweden, SE-50185 Contact: Johan Junelind, MD +46-36-321000 johan.junelind@lj.se Contact: Christer Oldin, MD +46-36-321000 christer.oldin@lj.se Principal Investigator: Johan Junelind, MD Sub-Investigator: Christer Oldin, MD Department of Anaesthesia & Intensive Care, University Hospital Not yet recruiting Linköping, Sweden, SE-58185 Contact: Anna Oscarsson, MD, PhD +46-10-1030000 ext 7784 anna.oscarsson.tibblin@lio.se Contact: Maria Sörliden, MD +46-1031000 maria.sorliden@lio.se Principal Investigator: Anna Oscarsson, MD, PhD Sub-Investigator: Maria Sörliden, MD Sub-Investigator: Anna-Karin Strand, MD Department of Anaesthesia & Intensive Care, University Hospital Not yet recruiting Örebro, Sweden, SE-70185 Contact: Anil Gupta, MD, PhD +46-196020256 anil.gupta@orebroll.se Contact: Jan Kuchalik, MD +46-196020256 jan.kuchalik@orebroll.se Principal Investigator: Anil Gupta, MD, PhD Sub-Investigator: Jan Kuchalik, MD Less << |
NCT00219388 | Heart Failure | Phase 4 | Completed | - | Sweden ... More >> Cardiology Department, Sahlgrenska University Hospital Gothenburg, Sweden, 413 45 Less << |
NCT02408003 | Heart Failure, Diastolic ... More >> Aortic Valve Stenosis Monitoring, Physiologic Physiology Less << | Not Applicable | Completed | - | Sweden ... More >> Thoraxoperation/TIVA, Sahlgrenska universitetssjukhuset Göteborg, Sweden, 413 45 Less << |
NCT01576094 | Low Cardiac Output Syndrome | Phase 1 Phase 2 | Completed | - | Spain ... More >> Hospital Universitario La Paz Madrid, Spain, 28046 Less << |
NCT01918618 | - | Completed | - | Germany ... More >> Charité - University Medicine Berlin Berlin, Germany, 10117 Less << | |
NCT01616069 | Cardiopulmonary Bypass Graft | Phase 4 | Completed | - | Brazil ... More >> National Institute of Cardiology / Ministry of Health Rio de janeiro, RJ, Brazil, 3600-100 Less << |
NCT00695929 | Congenital Cardiovascular Defe... More >>cts Low Cardiac Output Syndrome Less << | Not Applicable | Completed | - | Belgium ... More >> Cliniques Universitaires Saint Luc Brussels, Belgium, 1200 Less << |
NCT03189901 | Early Management ... More >> Acute Heart Failure NSTEMI - Non-ST Segment Elevation MI Less << | Phase 4 | Enrolling by invitation | December 31, 2021 | China, Shandong ... More >> Qilu Hospital of Shandong University Jinan, Shandong, China, 250012 Less << |
NCT00348504 | Acute Heart Failure | Phase 3 | Completed | - | United States, Illinois ... More >> Global Medical Information - Abbott Abbott Park, Illinois, United States, 60064 Less << |
NCT00549107 | Low Cardiac Output Syndrome | Phase 2 | Unknown | - | Austria ... More >> Children´s Heart Center Linz Recruiting Linz, Austria, 4020 Contact: Evelyn Lechner, MD elechner@aon.at Contact: Anna Hofer, MD anna.hofer@akh.linzat Principal Investigator: Evelyn Lechner, MD Principal Investigator: Anna Hofer, MD Less << |
NCT00048425 | Heart Failure, Congestive | Phase 3 | Completed | - | - |
NCT00093301 | Cardiogenic Shock ... More >> Septic Shock Less << | Phase 2 Phase 3 | Unknown | - | Australia, New South Wales ... More >> Intensive Care Unit, Nepean Hospital Recruiting Penrith, New South Wales, Australia, 2750 Contact: Anthony S McLean, MD +61-2-47342490 mcleana@wahs.nsw.gov.au Contact: Stephen J Huang, PhD +61-247342320 huangs@wahs.nsw.gov.au Principal Investigator: Anthony S McLean, MD Sub-Investigator: Stephen J Huang, PhD Sub-Investigator: Ian Seppelt, MD Sub-Investigator: Marek Nalos, MD Less << |
NCT02640846 | Septic Shock ... More >>Cardiomyopathy Less << | Phase 4 | Active, not recruiting | January 2019 | Sweden ... More >> Central intensivvårdsavdelning Sahlgrenska University Hospital Gothenburg, Västra Götaland, Sweden, 41345 Less << |
NCT02275013 | - | Completed | - | Germany ... More >> Charité University Medicine Berlin, Germany, 10117 Less << | |
NCT00527059 | Heart Failure ... More >> Renal Insufficiency Less << | Phase 4 | Unknown | March 2008 | Italy ... More >> Department of Cardiovascular, Respiratory and Morphological Sciences, University of Rome La Sapienza Not yet recruiting Rome, viale del Policlinico 155, Italy, 00161 Less << |
NCT00166127 | Heart Failure | Phase 3 | Terminated(Unable to renegotia... More >>te an expired contract w/sponsor providing study med) Less << | - | United States, Georgia ... More >> Emory University Hospital Atlanta, Georgia, United States, 30322 Less << |
NCT00610350 | Myocardial Protection | Phase 4 | Completed | - | Italy ... More >> University of Rome "Sapienza" Rome, Italy, 00155 Less << |
NCT00324766 | Myocardial Infarction ... More >> Heart Failure Cardiogenic Shock Less << | Phase 4 | Completed | - | Norway ... More >> Department of Cardiology, Ulleval University Hospital Oslo, Norway, N-0852 Less << |
NCT02487407 | Amyotrophic Lateral Sclerosis | Phase 2 | Completed | - | Germany ... More >> Charite Universitatsmedizin Berlin Berlin, Germany Medical School Hannover Hannover, Germany University Clinical Jena Jena, Germany University Hospital of Ulm Ulm, Germany Ireland Beaumont Hospital Dublin, Ireland Netherlands University Medical Centre Utrecht Utrecht, Netherlands United Kingdom Royal Sussex County Hospital Brighton, United Kingdom The Walton Centre Liverpool, United Kingdom London Kings College Hospital London, United Kingdom Royal London Hospital London, United Kingdom University of Sheffield Sheffield, United Kingdom Less << |
NCT00698763 | Transient Ischemic Attack ... More >> Stroke Less << | Phase 2 | Completed | - | Finland ... More >> Helsinki University Hospital (HUCH) Helsinki, Finland Turku University Hospital (TYKS) Turku, Finland, 20521 Germany Heidelberg University Clinic Heidelberg, Germany Hungary Debrecen University Debrecen, Hungary Sweden Sahlgrenska University Hospital, Dept of Neurology Gothenburg, Sweden, 413 45 University Hospital, Neurologmottagningen Linköping, Sweden, 581 85 Umeå University Hospital, Strokecenter NVS Umeå, Sweden, 901 85 Less << |
NCT00130884 | Chronic Heart Failure ... More >> Heart Diseases Less << | Phase 2 | Completed | - | Finland ... More >> Helsinki University Central Hospital Helsinki, Finland, 00029 Less << |
NCT00585104 | Heart Failure | Phase 2 | Completed | - | United States, Utah ... More >> University of Utah Salt Lake City, Utah, United States, 84112 Less << |
NCT02012946 | Cardiovascular Diseases | Phase 4 | Unknown | - | Italy ... More >> Francesco Pugliese Not yet recruiting Rome, Italy, 00100 Contact 00390649970468 mavif@tiscali.it Principal Investigator: francesco pugliese Less << |
NCT00130871 | Coronary Heart Disease | Phase 2 | Completed | - | Finland ... More >> Helsinki University Central Hospital Helsinki, Finland, 00290 Turku University Central Hospital Turku, Finland Less << |
NCT01704131 | - | Recruiting | November 2018 | Netherlands ... More >> PICU Leiden University Medical Center Recruiting Leiden, Netherlands Principal Investigator: Peter P Roeleveld, MD Less << | |
NCT03681379 | - | Not yet recruiting | October 1, 2020 | France ... More >> CHU de Nantes Nantes, France Less << | |
NCT00585104 | - | Completed | - | - | |
NCT00154115 | Heart Failure | Phase 4 | Completed | - | Finland ... More >> Kuopio University Hospital Kuopio, Finland, 70210 Less << |
NCT00800306 | Septic Shock | Phase 2 | Completed | - | Italy ... More >> Departement of Anesthesiology and Intensive Care of the University of Rome "La Sapienza" Viale del Policlinico 155 Rome, Italy, 00161 Less << |
NCT01101620 | Respiratory Muscle Function | Not Applicable | Completed | - | Netherlands ... More >> University Medical Center Nijmegen Nijmegen, Gelderland, Netherlands, 6525 GA Less << |
NCT01500785 | Myocardial Stunning | Phase 4 | Suspended(Change of schedule) | September 15, 2018 | Finland ... More >> Heart Center Co. Tampere university hospital Tampere, Finland, 33521 Less << |
NCT01595737 | Cardiac Surgery | Phase 4 | Completed | - | Spain ... More >> Hospital de la Santa Creu i Sant Pau Barcelona, Spain, 08025 Less << |
NCT01188369 | Diastolic Dysfunction ... More >> Left Ventricular Hypertrophy Less << | Phase 4 | Terminated(Terminated prematur... More >>ely due to high incidence of postoperative atrial fibrillation.) Less << | - | Denmark ... More >> Department of Anaesthesiology Århus N, Region Midtjylland, Denmark, 8200 Less << |
NCT03346824 | - | Recruiting | January 2019 | France ... More >> Service Réanimation chirurgicale cardiovasculaire-NHC Recruiting Strasbourg, France, 67091 Contact: Gharib AJOB, MD 33 3 69 55 15 70 gharib.ajob@chru-strasbourg.fr Contact: Guillaume HAFFNER, MD 33 3 69 55 15 70 guillaume.haffner@chru-strasbourg.fr Principal Investigator: Gharib AJOB, MD Sub-Investigator: Guillaume HAFFNER, MD Less << | |
NCT02232399 | Congenital Heart Defects | Phase 2 | Completed | - | Finland ... More >> Children´s Hospital, Helsinki University Central Hospital Helsinki, Finland, FIN-00029 HYKS Sweden Queen Silvia Children´s Hospital Göteborg, Västra Götaland, Sweden, 416 85 Less << |
NCT01210976 | Heart Valve Disease | Phase 4 | Completed | - | Finland ... More >> Tampere University Hospital Tampere, Finland Less << |
NCT00994825 | Low Cardiac Output Syndrome | Phase 4 | Completed | - | Brazil ... More >> Santa Casa de Misericórdia de Juiz de Fora Juiz de Fora, Minas Gerais, Brazil, 36.021- 630 Italy Azienda Ospedaliera Ospedali Riuniti Papardo - Piemonte Messina, ME, Italy, 98158 A.O.U. Citta della Salute e della Scienza Torino, TO, Italy, 10126 A. O. Ordine Mauriziano di Torino Torino, TO, Italy Ospedale San Bortolo Vicenza, VI, Italy Policlinico S.Orsola-Malpighi Bologna, Italy, 40138 Azienda Ospedaliera Universitaria "Mater Domini" Catanzaro, Italy Azienda Ospedaliera Universitaria San Martino Genova, Italy, 16132 Ospedale San Raffaele di Milano, Italy Milano, Italy, 20132 Ospedale San Gerardo di Monza Monza, Italy Azienda Ospedaliera Specialistica dei Colli Napoli, Italy Azienda Ospedaliera Universitaria Pisana Pisa, Italy Azienda Ospedaliera Regionale San Carlo Potenza, Italy, 85100 Ospedale Civile SS Annunziata Sassari, Italy Russian Federation Astrakhan Federal Centre for Cardiac Surgery Astrakhan, Russia, Russian Federation, 414000 Scientific Research Institute for Complex Issues of Cardiovascular Diseases Kemerovo, Russia, Russian Federation, 650002 Moscow Regional Clinical & Research Institute Moscow, Russia, Russian Federation, 129110 Research Institute of Circulation Pathology Novosibirsk, Russia, Russian Federation, 630055 Less << |
NCT03699215 | ST Elevation Myocardial Infarc... More >>tion Less << | Phase 3 | Not yet recruiting | November 30, 2020 | - |
NCT01290146 | Advanced Chronic Heart Failure | Phase 3 | Terminated(Due to lack of enro... More >>llment) Less << | - | Italy ... More >> Fondazione S. Maugeri. IRCCS Istituto di Cassano Murge Cassano Murge, Bari, Italy, 70020 Ospedali Riuniti di Ancona Cardiology Presidio Lancisi Ancona, Italy, 60020 Azienda Ospedaliero-Universitaria, Consorziale Policlinico di Bari, U.O. Cardiologia Universitaria, Dipartimento Emergenza e Trapianti di Organi Bari, Italy Ospedali Riuniti di Bergamo Cardiovascular Medicine Bergamo, Italy, 24128 Ospedale Brotzu Cardiology Cagliari, Italy, 09134 Ospedale Sant'Anna Cardiology Como, Italy, 22100 Ospedale SS Annunziata Cardiology Cosenza, Italy, 87100 Istituti Ospitalieri di Cremona Cardiology Cremona, Italy, 26100 Ospedale Santa Maria Nuova Cardiology Firenze, Italy, 50100 Ospedale Vito Fazzi Lecce, Italy, 73199 Istituto Auxologico Italiano - IRCCS Clinical Cardiology Cardiovascular Department Milan, Italy, 20148 Azienda Ospedaliera Niguarda Heart Failure and Heart Transplant Program Milan, Italy, 20162 Azienda Ospedaliera S. Gerardo Hear Failure and Cardiomyopathy Clinic Monza, Italy, 20052 Gruppo Policlinico di Monza Clinical Cardiology and Heart Failure Unit Cardiology Department Monza, Italy, 20052 Ospedale Santa Maria della Misericordia Cardiology Perugia, Italy, 06156 Ospedale Guglielmo da Saliceto Cardiology Department Piacenza, Italy, 29100 Azienda Ospedaliera San Camillo-Forlanini, Cardiology, Heart Failure Clinic Roma, Italy, 00151 Università di Roma Sapienza Dipartimento di Scienze Cardiovascolari e Respiratorie Roma, Italy, 00161 Azienda Ospedaliera San Giovanni- Addolorata 1st Cardiology Unit Roma, Italy, 00184 Ospedale Santo Spirito, Cardiology Roma, Italy, 00193 Azienda Ospedaliero-Universitaria, Ospedale di Cattinara Cardiology Trieste, Italy, 34149 Ospedale di Circolo e Fondazione Macchi Cardiology Varese, Italy, 21100 Less << |
NCT01188369 | - | Terminated(Terminated prematur... More >>ely due to high incidence of postoperative atrial fibrillation.) Less << | - | - | |
NCT02025621 | Coronary Artery Bypass Graftin... More >>g Mitral Valve Surgery Low Cardiac Output Syndrome Less << | Phase 3 | Completed | - | - |
NCT01065194 | Chronic Stable Heart Failure | Phase 3 | Unknown | August 2011 | Austria ... More >> Medical University Innsbruck Recruiting Innsbruck, Austria, 6020 Contact: Gerhard Poelzl, MD +43512504 ext 81318 gerhard.poelzl@uki.at Principal Investigator: Gerhard Poelzl, MD Allg. öffentliches Krankenhaus der Elisabethinen Recruiting Linz, Austria, 4010 Contact: Christian Ebner, MD +4373276760 christian.ebner@elisabethinen.or.at Principal Investigator: Christian Ebner, MD Krankenhaus der Barmherzigen Schwestern Recruiting Linz, Austria, 4010 Contact: Michael Mori, MD +437327677 michael.mori@bhs.at Principal Investigator: Peter Siostrzonek, MD Allgemeine Krankenhaus der Stadt Linz Recruiting Linz, Austria, 4021 Contact: Kurt Sihorsch, MD +437327806 ext 6235 kurt.sihorsch@akh.linz.at Principal Investigator: Franz Leisch, MD Paracelsus Medical University Salzburg Recruiting Salzburg, Austria, 5020 Contact: Johann Altenberger, MD +436624482 ext 57560 j.altenberger@salk.at Principal Investigator: Johann Altenberger, MD Landesklinikum St. Poelten Recruiting St. Poelten, Austria, 3100 Contact: Rudolf Berger, MD +432742300 ext 14706 rudolf.berger@stpoelten.lknoe.at Principal Investigator: Rudolf Berger, MD Kaiserin Elisabeth Spital Vienna Recruiting Vienna, Austria, 1150 Contact: Lida Dimopoulos-Xicki, MD +43/198104 ext 2108 Lida.Domopoulos-Xicki@wienkav.at Principal Investigator: Thomas Stefenelli, MD Klinikum Wels Grieskirchen Recruiting Wels, Austria, 4600 Contact: Thomas Weber, MD +437242415 ext 2215 Thomas.Weber@klinikum-wegr.at Principal Investigator: Thomas Weber, MD Greece G. Gennimatas General Hospital Recruiting Athens, Greece, 11527 Contact: Apostolos Karavidas, MD akaravid@yahoo.com Principal Investigator: Apostolos Karavidas, MD Hippokration General Hospital Recruiting Athens, Greece, 11527 Contact: Ekaterini Avgeropoulo, MD Principal Investigator: Ekaterini Avgeropoulo, MD Heart Failure Clinic, Attikon University Hospital Recruiting Athens, Greece, 12461 Contact: John Parissis, MD jparissis@yahoo.com Principal Investigator: John Parissis, MD Less << |
NCT02963454 | Septic Shock | Not Applicable | Recruiting | February 2018 | Tunisia ... More >> Military Hopital of Tunis Recruiting Tunis, Tunisia, 1008 Contact: zied hajjej 20358907 ext 00216 hajjej_zied@hotmail.com Contact: mustapha ferjani 98329256 ext 00216 mustapha.ferjani@planet.tn Less << |
NCT02973620 | - | - | - | - | |
NCT02133105 | Cardiorenal Syndrome | Phase 3 | Enrolling by invitation | December 2017 | Sweden ... More >> Sahlgrenska University Hospital Gothenburg, Sweden, 41345 Less << |
NCT01022983 | Heart Failure ... More >> Hip Fracture Less << | Phase 4 | Withdrawn(Not finding patients... More >> for including) Less << | - | Norway ... More >> Oslo University Hospital - Ullevål Oslo, Norway Vestfold Hospital Trust Tonsberg, Norway, 3103 Sweden Mölndal Hospital Gothenburg, Sweden Universitety Hospital Örebro Hudiksvall, Sweden Less << |
NCT01221116 | Heart Failure ... More >> Cardiac Surgery Less << | Not Applicable | Terminated(The study was stopp... More >>ed due to difficulties in including patients) Less << | - | Norway ... More >> Dept. of Cardiothoracic Anesthesia, Ullevål University Hospital Oslo, Norway, 0407 Less << |
NCT02025621 | - | Completed | - | - | |
NCT01536132 | Heart Failure | Phase 4 | Completed | - | Spain ... More >> Hospistal Central Asturias Oviedo, Asturias, Spain, 33006 Hospital de Bellvitge Hospitalet de Llobregat, Barcelona, Spain, 08907 Hospital Puerta de Hierro Majadahonda, Madrid, Spain, 28222 Complexo Hospitalario A Coruña A Coruña, Spain, 15006 Hospital del Mar Barcelona, Spain, 08003 Hospital de Sant Pau Barcelona, Spain, 08040 Hospital Doce de Octubre Madrid, Spain, 28041 Hospital Virgen de la Victoria Malaga, Spain, 29010 Hospital Virgen Arrixaca Murcia, Spain, 41013 Hospital Valdecillas Santander, Spain, 39008 Hospital Virgen del Rocío Sevilla, Spain, 41013 Hospital la Fe Valencia, Spain, 46026 Hospital Miguel Servet Zaragoza, Spain, 50009 Less << |
NCT01318460 | Coronary Artery Disease | Phase 4 | Completed | - | Greece ... More >> Department of Cardiothoracic Surgery, AHEPA University Hospital Thessaloniki, Greece, 546 36 Less << |
NCT01721434 | Muscle Weakness Conditions ... More >> Weaning Failure Less << | Phase 2 Phase 3 | Unknown | May 2016 | Netherlands ... More >> Radboud University Nijmegen Medical Centre Recruiting Nijmegen, Gelderland, Netherlands, 6500HB Contact: Leo MA Heunks, MD, PhD 024-3617273 l.heunks@ic.umcn.nl Contact: Jonne Doorduin, MSc 024-3617273 j.doorduin@ic.umcn.nl Less << |
NCT02184819 | Coronary Artery Bypass Graftin... More >>g Left Ventricular Dysfonction Less << | Phase 3 | Completed | - | France ... More >> Hôpital Européen Georges Pompidou, Assistance Publique Hôpitaux de Paris, France Paris, France, 75015 Less << |
NCT01301313 | Acute Heart Failure | Phase 2 | Terminated | - | Spain ... More >> Hospital Donosti Donostia, San Sebastian, Spain Hospital Clínico Universitario de Santiago de Compostela A Coruña, Spain Hospital Juan Canalejo A Coruña, Spain Hospital San Joan de Deu Barcelona, Spain Hospital Universitario Reina Sofía Córdoba, Spain Hospital Universitario Ramon y Cajal Madrid, Spain, 28034 Hospital General Universitario Gregorio Marañón Madrid, Spain Hospital Infantil La Paz Madrid, Spain Hospital Universitario Doce de Octubre Madrid, Spain Hospital Universitario Carlos Haya Malaga, Spain Hospital Virgen de la Arrixaca Murcia, Spain Hospital Clínico Universitario Son Dureta Palma de Mallorca, Spain Complejo Hospitalario Universitario de Salamanca Salamanca, Spain Hospital Virgen de la Salud Toledo, Spain Hospital Clínico de Valencia Valencia, Spain Hospital La Fe Valencia, Spain Hospital Clínico Universitario de Valladolid Valladolid, Spain Hospital de Cruces Vizcaya, Spain Hospital Miguel Servet Zaragoza, Spain Less << |
NCT01720030 | Acute Kidney Injury | Phase 2 Phase 3 | Unknown | October 2017 | Netherlands ... More >> VieCuri Medical Center Venlo, Limburg, Netherlands, NL-5912 BL Less << |
NCT03541603 | Hypertension Pulmonary Seconda... More >>ry Heart Failure, Right Sided Heart Failure With Normal Ejection Fraction Less << | Phase 2 | Recruiting | December 2019 | United States, Arizona ... More >> Banner University Medical Center Phoenix Lung Institute Recruiting Phoenix, Arizona, United States, 85006 United States, California Stanford Healthcare Recruiting Stanford, California, United States, 94305 United States, New York Mayo Clinic Recruiting Rochester, New York, United States, 55905 Less << |
NCT03624010 | Hypertension Pulmonary Seconda... More >>ry Heart Failure Right Sided Heart Failure With Normal Ejection Fraction Heart Failure With Normal Ejection Fraction Less << | Phase 2 | Recruiting | December 2021 | United States, Arizona ... More >> Banner University Phoenix Lung Institute Recruiting Phoenix, Arizona, United States, 85006 United States, California Stanford Healthcare Recruiting Stanford, California, United States, 94305 United States, Minnesota Mayo Clinic Recruiting Rochester, Minnesota, United States, 55905 United States, New York North Shore University Hospital Active, not recruiting Manhasset, New York, United States, 11030 Less << |
NCT01120106 | Low Cardiac Output Syndrome | Phase 2 | Completed | - | Italy ... More >> Bambino Gesù Hospital Rome, Italy, 00165 Less << |
NCT03557255 | Heart Failure | Phase 2 | Completed | - | Egypt ... More >> Department of Anesthesia and Pain medicine.National Cancer Institute Cairo, Egypt, 11796 Less << |
NCT02261948 | - | Completed | - | - | |
NCT03022877 | Myocardial Infarction ... More >> Outcome Less << | Not Applicable | Not yet recruiting | December 2018 | - |
NCT02531724 | Acute Kidney Injury ... More >> Renal Insufficiency, Acute Less << | Phase 4 | Recruiting | December 2018 | Sweden ... More >> Department of thoracic anesthesia, Sahlgrenska University Hospital Recruiting Gothenburg, Sweden, 41345 Contact: Lukas Lannemyr, MD +46-31-3428860 lukas.lannemyr@vgregion.se Contact: Sven-Erik Ricksten, Professor sven-erik.ricksten@aniv.gu.se Less << |
NCT03576677 | Heart Failure | Phase 4 | Not yet recruiting | July 30, 2020 | Denmark ... More >> Department of Cardiology, The Heart Center, Copenhagen University Hospital, Rigshospitalet Not yet recruiting Copenhagen, Denmark, DK-2100 Contact: Finn Gustafsson, MD, professor, PhD, DMSci +45 35459743 finng@dadlnet.dk Contact: Lærke Nelson, MD +45 35459549 laerke.marie.nelson@regionh.dk Principal Investigator: Finn Gustafsson, MD, professor, PhD, DMSci Sub-Investigator: Lærke Nelson, MD Department of Cardiology, Copenhagen University Hospital, Herlev and Gentofte Hospital, Herlev, Denmark Not yet recruiting Herlev, Denmark, DK-2730 Contact: Morten Schou, MD, PhD +45 40523920 schou@dadlnet.dk Principal Investigator: Morten Schou, MD, PhD Department of Cardiology, Odense University Hospital, Odense, Denmark Not yet recruiting Odense, Denmark, DK-5000 Contact: Jacob E Møller, MD, professor, PhD, DMSci +45 51439630 jem@dadlnet.do Contact: Mikael K Poulsen, MD, PhD +45 24798402 mikael.kjaer.poulsen1@rsyd.dk Principal Investigator: Jacob E Møller, MD, professor, PhD, DMSci Sub-Investigator: Mikael K Poulsen, PhD Less << |
NCT00988806 | Advanced Heart Failure | Phase 4 | Unknown | December 2014 | Spain ... More >> Department of Cardiology. Hospital Universitario de Canarias La Laguna, S.C. de Tenerife, Spain, 38320 Less << |
NCT02972918 | Ventricular Dysfunction, Left ... More >> Hip Fracture Less << | Not Applicable | Recruiting | December 2018 | Spain ... More >> Complejo Hospitalario Universitario de Canarias Recruiting La Laguna, S/c Tenerife, Spain, 38320 Contact: Magali González-Colaço Harmand, MD, PhD +34 922675557 magaligch@hotmail.com Contact: ANA ALDEA, MD, PhD +34922678115 a.aldea@gmail.com Principal Investigator: María del Carmen Martín Lorenzo, MD Less << |
NCT02261948 | Heart Failure | Phase 4 | Completed | - | Italy ... More >> Centro Cardiologico Monzino Milano, MI, Italy, 20138 Less << |
NCT03659851 | - | Recruiting | December 31, 2018 | Croatia ... More >> Nikola Bradic Recruiting Zagreb, Croatia, 10000 Contact: Nikola Bradic, MD +385 91 589 3480 nbradic@kbd.hr Less << | |
NCT03437226 | Heart Failure | Phase 3 | Recruiting | December 31, 2019 | Austria ... More >> Medical University Innsbruck Recruiting Innsbruck, Tirol, Austria, 6020 Contact: Kathrin Becker, PhD +43512900371 ext 844 leodor@i-med.ac.at Contact: Sabine Embache-Aichhorn +43512900370 ext 086 leodor@i-med.ac.at Less << |
NCT03505021 | Amyotrophic Lateral Sclerosis | Phase 3 | Recruiting | October 30, 2020 | - |
NCT03764722 | Systolic Heart Failure | Phase 4 | Recruiting | December 31, 2021 | Poland ... More >> Second Department of Cardiology Recruiting Bydgoszcz, Poland, 85-168 Less << |
NCT01969071 | Mitral Valve Stenosis With Inc... More >>ompetence or Regurgitation Less << | Phase 4 | Completed | - | Turkey ... More >> Kartal Kosuyolu High Speciality Training and Research Hospital Istanbul, Turkey, 34846 Less << |
Bio Calculators | ||||
Preparing Stock Solutions | ![]() | 1mg | 5mg | 10mg |
1 mM 5 mM 10 mM | 3.57mL 0.71mL 0.36mL | 17.84mL 3.57mL 1.78mL | 35.68mL 7.14mL 3.57mL |
Tags: Levosimendan | Simsndan | 141505-33-1
Precautionary Statements-General | |
Code | Phrase |
P101 | If medical advice is needed,have product container or label at hand. |
P102 | Keep out of reach of children. |
P103 | Read label before use |
Prevention | |
Code | Phrase |
P201 | Obtain special instructions before use. |
P202 | Do not handle until all safety precautions have been read and understood. |
P210 | Keep away from heat/sparks/open flames/hot surfaces. - No smoking. |
P211 | Do not spray on an open flame or other ignition source. |
P220 | Keep/Store away from clothing/combustible materials. |
P221 | Take any precaution to avoid mixing with combustibles |
P222 | Do not allow contact with air. |
P223 | Keep away from any possible contact with water, because of violent reaction and possible flash fire. |
P230 | Keep wetted |
P231 | Handle under inert gas. |
P232 | Protect from moisture. |
P233 | Keep container tightly closed. |
P234 | Keep only in original container. |
P235 | Keep cool |
P240 | Ground/bond container and receiving equipment. |
P241 | Use explosion-proof electrical/ventilating/lighting/equipment. |
P242 | Use only non-sparking tools. |
P243 | Take precautionary measures against static discharge. |
P244 | Keep reduction valves free from grease and oil. |
P250 | Do not subject to grinding/shock/friction. |
P251 | Pressurized container: Do not pierce or burn, even after use. |
P260 | Do not breathe dust/fume/gas/mist/vapours/spray. |
P261 | Avoid breathing dust/fume/gas/mist/vapours/spray. |
P262 | Do not get in eyes, on skin, or on clothing. |
P263 | Avoid contact during pregnancy/while nursing. |
P264 | Wash hands thoroughly after handling. |
P265 | Wash skin thouroughly after handling. |
P270 | Do not eat, drink or smoke when using this product. |
P271 | Use only outdoors or in a well-ventilated area. |
P272 | Contaminated work clothing should not be allowed out of the workplace. |
P273 | Avoid release to the environment. |
P280 | Wear protective gloves/protective clothing/eye protection/face protection. |
P281 | Use personal protective equipment as required. |
P282 | Wear cold insulating gloves/face shield/eye protection. |
P283 | Wear fire/flame resistant/retardant clothing. |
P284 | Wear respiratory protection. |
P285 | In case of inadequate ventilation wear respiratory protection. |
P231 + P232 | Handle under inert gas. Protect from moisture. |
P235 + P410 | Keep cool. Protect from sunlight. |
Response | |
Code | Phrase |
P301 | IF SWALLOWED: |
P304 | IF INHALED: |
P305 | IF IN EYES: |
P306 | IF ON CLOTHING: |
P307 | IF exposed: |
P308 | IF exposed or concerned: |
P309 | IF exposed or if you feel unwell: |
P310 | Immediately call a POISON CENTER or doctor/physician. |
P311 | Call a POISON CENTER or doctor/physician. |
P312 | Call a POISON CENTER or doctor/physician if you feel unwell. |
P313 | Get medical advice/attention. |
P314 | Get medical advice/attention if you feel unwell. |
P315 | Get immediate medical advice/attention. |
P320 | |
P302 + P352 | IF ON SKIN: wash with plenty of soap and water. |
P321 | |
P322 | |
P330 | Rinse mouth. |
P331 | Do NOT induce vomiting. |
P332 | IF SKIN irritation occurs: |
P333 | If skin irritation or rash occurs: |
P334 | Immerse in cool water/wrap n wet bandages. |
P335 | Brush off loose particles from skin. |
P336 | Thaw frosted parts with lukewarm water. Do not rub affected area. |
P337 | If eye irritation persists: |
P338 | Remove contact lenses, if present and easy to do. Continue rinsing. |
P340 | Remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P341 | If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P342 | If experiencing respiratory symptoms: |
P350 | Gently wash with plenty of soap and water. |
P351 | Rinse cautiously with water for several minutes. |
P352 | Wash with plenty of soap and water. |
P353 | Rinse skin with water/shower. |
P360 | Rinse immediately contaminated clothing and skin with plenty of water before removing clothes. |
P361 | Remove/Take off immediately all contaminated clothing. |
P362 | Take off contaminated clothing and wash before reuse. |
P363 | Wash contaminated clothing before reuse. |
P370 | In case of fire: |
P371 | In case of major fire and large quantities: |
P372 | Explosion risk in case of fire. |
P373 | DO NOT fight fire when fire reaches explosives. |
P374 | Fight fire with normal precautions from a reasonable distance. |
P376 | Stop leak if safe to do so. Oxidising gases (section 2.4) 1 |
P377 | Leaking gas fire: Do not extinguish, unless leak can be stopped safely. |
P378 | |
P380 | Evacuate area. |
P381 | Eliminate all ignition sources if safe to do so. |
P390 | Absorb spillage to prevent material damage. |
P391 | Collect spillage. Hazardous to the aquatic environment |
P301 + P310 | IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
P301 + P312 | IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
P301 + P330 + P331 | IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. |
P302 + P334 | IF ON SKIN: Immerse in cool water/wrap in wet bandages. |
P302 + P350 | IF ON SKIN: Gently wash with plenty of soap and water. |
P303 + P361 + P353 | IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. |
P304 + P312 | IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell. |
P304 + P340 | IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. |
P304 + P341 | IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. |
P305 + P351 + P338 | IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
P306 + P360 | IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes. |
P307 + P311 | IF exposed: call a POISON CENTER or doctor/physician. |
P308 + P313 | IF exposed or concerned: Get medical advice/attention. |
P309 + P311 | IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician. |
P332 + P313 | IF SKIN irritation occurs: Get medical advice/attention. |
P333 + P313 | IF SKIN irritation or rash occurs: Get medical advice/attention. |
P335 + P334 | Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages. |
P337 + P313 | IF eye irritation persists: Get medical advice/attention. |
P342 + P311 | IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. |
P370 + P376 | In case of fire: Stop leak if safe to Do so. |
P370 + P378 | In case of fire: |
P370 + P380 | In case of fire: Evacuate area. |
P370 + P380 + P375 | In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion. |
P371 + P380 + P375 | In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion. |
Storage | |
Code | Phrase |
P401 | |
P402 | Store in a dry place. |
P403 | Store in a well-ventilated place. |
P404 | Store in a closed container. |
P405 | Store locked up. |
P406 | Store in corrosive resistant/ container with a resistant inner liner. |
P407 | Maintain air gap between stacks/pallets. |
P410 | Protect from sunlight. |
P411 | |
P412 | Do not expose to temperatures exceeding 50 oC/ 122 oF. |
P413 | |
P420 | Store away from other materials. |
P422 | |
P402 + P404 | Store in a dry place. Store in a closed container. |
P403 + P233 | Store in a well-ventilated place. Keep container tightly closed. |
P403 + P235 | Store in a well-ventilated place. Keep cool. |
P410 + P403 | Protect from sunlight. Store in a well-ventilated place. |
P410 + P412 | Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF. |
P411 + P235 | Keep cool. |
Disposal | |
Code | Phrase |
P501 | Dispose of contents/container to ... |
P502 | Refer to manufacturer/supplier for information on recovery/recycling |
Physical hazards | |
Code | Phrase |
H200 | Unstable explosive |
H201 | Explosive; mass explosion hazard |
H202 | Explosive; severe projection hazard |
H203 | Explosive; fire, blast or projection hazard |
H204 | Fire or projection hazard |
H205 | May mass explode in fire |
H220 | Extremely flammable gas |
H221 | Flammable gas |
H222 | Extremely flammable aerosol |
H223 | Flammable aerosol |
H224 | Extremely flammable liquid and vapour |
H225 | Highly flammable liquid and vapour |
H226 | Flammable liquid and vapour |
H227 | Combustible liquid |
H228 | Flammable solid |
H229 | Pressurized container: may burst if heated |
H230 | May react explosively even in the absence of air |
H231 | May react explosively even in the absence of air at elevated pressure and/or temperature |
H240 | Heating may cause an explosion |
H241 | Heating may cause a fire or explosion |
H242 | Heating may cause a fire |
H250 | Catches fire spontaneously if exposed to air |
H251 | Self-heating; may catch fire |
H252 | Self-heating in large quantities; may catch fire |
H260 | In contact with water releases flammable gases which may ignite spontaneously |
H261 | In contact with water releases flammable gas |
H270 | May cause or intensify fire; oxidizer |
H271 | May cause fire or explosion; strong oxidizer |
H272 | May intensify fire; oxidizer |
H280 | Contains gas under pressure; may explode if heated |
H281 | Contains refrigerated gas; may cause cryogenic burns or injury |
H290 | May be corrosive to metals |
Health hazards | |
Code | Phrase |
H300 | Fatal if swallowed |
H301 | Toxic if swallowed |
H302 | Harmful if swallowed |
H303 | May be harmful if swallowed |
H304 | May be fatal if swallowed and enters airways |
H305 | May be harmful if swallowed and enters airways |
H310 | Fatal in contact with skin |
H311 | Toxic in contact with skin |
H312 | Harmful in contact with skin |
H313 | May be harmful in contact with skin |
H314 | Causes severe skin burns and eye damage |
H315 | Causes skin irritation |
H316 | Causes mild skin irritation |
H317 | May cause an allergic skin reaction |
H318 | Causes serious eye damage |
H319 | Causes serious eye irritation |
H320 | Causes eye irritation |
H330 | Fatal if inhaled |
H331 | Toxic if inhaled |
H332 | Harmful if inhaled |
H333 | May be harmful if inhaled |
H334 | May cause allergy or asthma symptoms or breathing difficulties if inhaled |
H335 | May cause respiratory irritation |
H336 | May cause drowsiness or dizziness |
H340 | May cause genetic defects |
H341 | Suspected of causing genetic defects |
H350 | May cause cancer |
H351 | Suspected of causing cancer |
H360 | May damage fertility or the unborn child |
H361 | Suspected of damaging fertility or the unborn child |
H361d | Suspected of damaging the unborn child |
H362 | May cause harm to breast-fed children |
H370 | Causes damage to organs |
H371 | May cause damage to organs |
H372 | Causes damage to organs through prolonged or repeated exposure |
H373 | May cause damage to organs through prolonged or repeated exposure |
Environmental hazards | |
Code | Phrase |
H400 | Very toxic to aquatic life |
H401 | Toxic to aquatic life |
H402 | Harmful to aquatic life |
H410 | Very toxic to aquatic life with long-lasting effects |
H411 | Toxic to aquatic life with long-lasting effects |
H412 | Harmful to aquatic life with long-lasting effects |
H413 | May cause long-lasting harmful effects to aquatic life |
H420 | Harms public health and the environment by destroying ozone in the upper atmosphere |
Sorry,this product has been discontinued.
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