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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 50-33-9 Chemical Structure| 50-33-9
Chemical Structure| 50-33-9

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Phenylbutazone is used as a non-steroidal anti-inflammatory agent for the treatment of chronic pain, including the symptoms of arthritis.

Synonyms: Butazolidine

4.5 *For Research Use Only !

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Product Citations

Product Citations

Lifen Chen ; Kim Quayle ; Zoe M. Smith ; Timothy U. Connell ; Egan H. Doeven ; David J. Hayne , et al.

Abstract: Background: Iridium(III) complexes, exhibiting high luminescence quantum yields and a wide range of emission colours, are promising alternatives to tris(2,2ʹ-bipyridine)ruthenium(II) for chemiluminescence (CL) and electrochemiluminescence (ECL) detection. This emerging class of reagent, however, is limited by the poor solubility of many iridium(III) complexes in aqueous solution, and lack of understanding of their remarkably variable selectivities towards different analytes. Results: Seven [Ir(C^N)2(pt-TEG)]+ complexes, exhibiting a wide range of reduction potentials and emission energies, were examined with six model analytes. For CL, cerium(IV) was used as the oxidant. The alkylamine analytes generally produced greater CL and ECL with the more readily oxidised Ir(III) complexes (C^N = piq, bt, ppy), predominantly through the ‘direct’ pathway requiring oxidation of both metal complex and analyte. derivatives that did not also contain secondary or tertiary alkylamines elicited CL from the less readily oxidised complexes (C^N = df-ppy-CF3, df-ppy) via energy transfer. The most difficult to oxidise complexes (C^N = df(CF3)-ppy-Me, df(CN)-ppy) gave poor responses due to the limited potential window of the solvent and inefficiency of energy transfer to their high energy excited states. Greater CL and/or ECL intensities were generally obtained for each analyte with at least one Ir(III) complex than with [Ru(bpy)3]2+; superior limits of detection for two analytes were demonstrated. Significance: This exploration of CL/ECL in which the properties of luminophore, analyte and oxidant are all varied provides a new understanding of the influence of the metal-complex potentials and excited state energy on the light-producing and quenching pathways, and consequently, their distinct selectivity towards different analytes. These findings will guide the development of water-soluble Ir(III) complexes as CL and ECL reagents.

Keywords: Chemiluminescence detection ; Electrochemiluminescence detection ; Electrogenerated chemiluminescence detection ; Iridium(III) complexes

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Product Details of Phenylbutazone

CAS No. :50-33-9
Formula : C19H20N2O2
M.W : 308.37
SMILES Code : O=C(C1CCCC)N(C2=CC=CC=C2)N(C3=CC=CC=C3)C1=O
Synonyms :
Butazolidine
MDL No. :MFCD00005500
InChI Key :VYMDGNCVAMGZFE-UHFFFAOYSA-N
Pubchem ID :4781

Safety of Phenylbutazone

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P310+P330-P405
Class:6.1
UN#:2811
Packing Group:
 

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